Abstract: An imaging device and a method using the imaging device for acquiring in vivo images of a region of a subject's body. The imaging device comprises at least two energy sources, and at least two energy detectors for detecting energy from the at least two energy sources passing through the region of the subject's body. The imaging device also comprises a motion assembly configured to achieve relative movement between a source-detector pair comprising at least one of the energy source and energy detectors, and the subject, and a controller for operating the energy sources and detectors while stationary, to acquire a time series of in vivo images of the region of the subject's body, and operating the motion assembly and the source-detector pair to achieve relative movement therebetween to obtain a second set of images at each of a plurality of image angles in a plane of the source-detector pair.

Abstract: An imaging device for acquiring a time series of in vivo images of a region of a subject's body is provided. The imaging device includes a energy source, a detector for detecting energy from the energy source passing through the region of the subject's body located between the energy source and detector, a controller configured to operate the energy source and the detector to acquire a time series of in vivo images of the region of the subject's body, a sensor for monitoring a physiological parameter associated with the region of the subject's body to be imaged and a processor configured to determine timing of the image acquisition based at least on the monitored physiological parameter. A method for acquiring a time series of in vivo images of a region of a subject's body using the imaging device is also provided.