Abstract: A spinal implant comprises an implant body extending between an anterior surface and a posterior surface and includes a first vertebral engaging surface and a second vertebral engaging surface. The implant body includes an inner surface that defines at least one cavity that is oriented to implant a fastener oblique relative to a lateral axis of a subject body and adjacent an intervertebral space of the subject body. At least one indicia is disposed with the implant body to facilitate orientation of the implant body with the subject body. Systems and methods are disclosed.

Abstract: An interbody implant system is provided. The interbody implant system includes an implant having an engagement surface and an instrument including a first member and a second member that is movable relative to the first member. The first member is configured to capture the implant and the second member includes an interface configured to engage the engagement surface to releasably lock the implant in at least one orientation relative to the second member. The at least one of the engagement surface and the interface include at least one planar face. Methods of use are disclosed.

Abstract: An interbody endcap comprises at least one member configured for connection with an interbody implant. The at least one member has a thickness that permits bone growth therethrough and a uniform surface configuration that resists and/or prevents egress of bone graft from a cavity of the interbody implant. Systems and methods are disclosed.

Abstract: A spinal implant comprises an implant body extending between an anterior surface and a posterior surface and includes a first vertebral engaging surface and a second vertebral engaging surface. The implant body includes an inner surface that defines at least one cavity that is oriented to implant a fastener oblique relative to a lateral axis of a subject body and adjacent an intervertebral space of the subject body. The implant body includes an oblique surface that defines at least one opening disposed in substantial alignment with the at least one cavity. Systems and methods are disclosed.

Abstract: Embodiments of the invention include a medical implant having a vertebral body replacement device, alone or in combination with other complimentary elements, configured to deliver one or more therapeutic substances. The one or more therapeutic substances may be contained in the medical implant or be ported to the medical implant.

Abstract: A system for treating a lumbo-sacral junction includes at least one dilator configured to create a passageway from a direct lateral trajectory in a body defining a longitudinal axis. A cutting instrument is configured to create a bore, oriented at an angle from the longitudinal axis, in a L5 vertebrae of the body extending to a central portion of a L5-S1 intervertebral disc space of the body. A delivery instrument is configured to deliver an implant through the bore to the central portion of the L5-S1 disc space. Methods of use are disclosed.

Abstract: Embodiments of the invention include a device for supplementing or replacing a spinal structure and therapeutically delivering radiation to tissue. Some embodiments include a radiation source and a combination of members surrounding the radiation source that move relative to one another to permit or restrict emission of radiation from the device.

Abstract: An implant for insertion between adjacent vertebral members, comprising an implant body with a base section having positioning teeth, and an end cap for positioning at a selected point on the base section via adjustment of an approach direction. The end cap comprises a seating surface which contacts the base section when positioned on the implant body, an end cap angulation, and positioning passages for receiving positioning teeth. The implant may comprise a locking mechanism for lockingly engaging the end cap and base section and preventing end cap axial movement. The positioning passages and positioning teeth configured to facilitate end cap slideable positioning on the base section. And, a positioning passage comprising a locking tenon for lockingly engaging a positioning tooth in the positioning passage. The implant body and end cap combination imparting angulation to an adjacent vertebral body at the selected point when positioned in the intervertebral space.