Patents by Inventor Jonathan E. Page

Jonathan E. Page has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11396656
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: July 26, 2022
    Assignee: 22nd Century Limited, LLC
    Inventors: Jonathan E. Page, Enwu Liu
  • Publication number: 20220195473
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: March 10, 2022
    Publication date: June 23, 2022
    Inventors: Jonathan E. Page, Steve Gagne
  • Patent number: 11306335
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: April 19, 2022
    Assignees: NATIONAL RESEARCH COUNCIL OF CANADA, UNIVERSITY OF SASKATCHEWAN
    Inventors: Jonathan E. Page, Steve Gagne
  • Publication number: 20200325508
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 15, 2020
    Inventors: Jonathan E. Page, Steve Gagne
  • Publication number: 20200277616
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Application
    Filed: May 18, 2020
    Publication date: September 3, 2020
    Applicant: 22nd Century Limited, LLC
    Inventors: Jonathan E. Page, Enwu Liu
  • Patent number: 10724009
    Abstract: Nucleic acid molecules from cannabis have been isolated and characterized and encode polypeptides having cannabichromenic acid synthase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: July 28, 2020
    Assignee: National Research Council of Canada (NRC)
    Inventors: Jonathan E. Page, Jason M. Stout
  • Patent number: 10718000
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: July 21, 2020
    Assignees: National Research Council of Canada, University of Saskatchewan
    Inventors: Jonathan E. Page, Steve Gagne
  • Patent number: 10689658
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: June 23, 2020
    Assignee: 22nd Century Limited, LLC
    Inventors: Jonathan E. Page, Enwu Liu
  • Publication number: 20190382734
    Abstract: Nucleic acid molecules from cannabis have been isolated and characterized and encode polypeptides having cannabichromenic acid synthase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: June 17, 2019
    Publication date: December 19, 2019
    Inventors: Jonathan E. Page, Jason M. Stout
  • Patent number: 10364416
    Abstract: Nucleic acid molecules from cannabis have been isolated and characterized and encode polypeptides having cannabichromenic acid synthase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: July 30, 2019
    Assignee: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Jonathan E. Page, Jason M. Stout
  • Publication number: 20190169661
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: August 1, 2018
    Publication date: June 6, 2019
    Inventors: Jonathan E. Page, Steve Gagne
  • Publication number: 20190032069
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Application
    Filed: August 3, 2018
    Publication date: January 31, 2019
    Applicant: 22ND CENTURY LIMITED, LLC
    Inventors: JONATHAN E. PAGE, ENWU LIU
  • Patent number: 10059971
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: August 28, 2018
    Assignees: National Research Council of Canada, University of Saskatchewan
    Inventors: Jonathan E. Page, Steve Gagne
  • Patent number: 10041084
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: August 7, 2018
    Assignee: 22nd Century Limited, LLC
    Inventors: Jonathan E. Page, Enwu Liu
  • Patent number: 9765308
    Abstract: Nucleic acid molecules from cannabis has been isolated and characterized and encode polypeptides having aromatic prenyltransferase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: September 19, 2017
    Assignees: The University of Saskatchewan, National Research Council of Canada
    Inventors: Jonathan E. Page, Zakia Boubakir
  • Publication number: 20170233779
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: February 21, 2017
    Publication date: August 17, 2017
    Inventors: Jonathan E. Page, Steve Gagne
  • Publication number: 20170211049
    Abstract: Nucleic acid molecules from cannabis have been isolated and characterized and encode polypeptides having cannabi-chromenic acid synthase activity. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Application
    Filed: June 29, 2015
    Publication date: July 27, 2017
    Inventors: Jonathan E. Page, Jason M. Stout
  • Patent number: 9611460
    Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: April 4, 2017
    Assignees: NATIONAL RESEARCH COUNCIL OF CANADA, UNIVERSITY OF SASKATCHEWAN
    Inventors: Jonathan E. Page, Steve Gagne
  • Publication number: 20170044564
    Abstract: The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently or with other alkaloid biosynthesis genes to modulate alkaloid production in plants and host cells. MPO genes or fragments thereof are useful for reducing pyrrolidine or tropane alkaloid production in plants, for increasing pyrrolidine or tropane alkaloid production in plants, and for producing an MPO enzyme in host cells.
    Type: Application
    Filed: August 19, 2016
    Publication date: February 16, 2017
    Applicant: 22nd Century Limited, LLC
    Inventors: Jonathan E. Page, Enwu Liu
  • Patent number: 9546362
    Abstract: Polypeptides having alkanoyl-CoA activity have been identified and characterized, as have nucleic acids encoding these polypeptides. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: January 17, 2017
    Assignees: National Research Council of Canada, University of Saskatchewan
    Inventors: Jonathan E. Page, Jason M. Stout