Patents by Inventor Jonathan E. Wilson

Jonathan E. Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • P300/CBP HAT INHIBITORS
    Publication number: 20250230137
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone acetyltransferase (HAT).
    Type: Application
    Filed: August 29, 2024
    Publication date: July 17, 2025
    Inventors: Jonathan E. Wilson, Francois Brucelle, Julian R. Levell
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20250197357
    Abstract: Provided are compounds of Formula (I); and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 19, 2025
    Inventor: Jonathan E. Wilson
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20250186425
    Abstract: Provided are compounds of Formula (I); and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 12, 2025
    Inventor: Jonathan E. Wilson
  • MODULATORS OF TREX1
    Publication number: 20250136588
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositons thereof. which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: November 6, 2024
    Publication date: May 1, 2025
    Inventors: Anna Gardberg, Victor S. Gehling, Avinash Khanna, Julian R. Levell, Jonathan E. Wilson, Kennedy Taveras
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20250122169
    Abstract: Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: August 4, 2022
    Publication date: April 17, 2025
    Inventors: Jonathan E. Wilson, James E. Audia, Jacob I. Stuckey, Mark Scott
  • METHODS AND APPARATUS FOR INVERTING A HOLLOW SLEEVE AND THEREAFTER REVERTING AN INVERTED HOLLOW SLEEVE
    Publication number: 20250107690
    Abstract: Apparatus for inverting an elongated flexible tubular sleeve having a proximal end, a distal end and a central lumen extending between the proximal end and the distal end, the apparatus comprising: a hollow tube comprising a proximal end, a distal end and a central lumen extending between the proximal end and the distal end; and an elongated rod movably disposed within the central lumen of the hollow tube, the elongated rod having a proximal end and a distal end, wherein the distal end of the elongated rod comprises a sleeve plug for securing a distal end of an elongated flexible tubular sleeve to the distal end of the hollow tube; wherein, when the elongated flexible tubular sleeve is disposed over the hollow tube, (i) the sleeve plug of the elongated rod is configured to be moved proximally to clamp the distal end of the elongated flexible tubular sleeve to the distal end of the hollow tube, and (ii) the sleeve plug of the elongated rod is configured to be moved distally to release the distal end of the elo
    Type: Application
    Filed: July 2, 2024
    Publication date: April 3, 2025
    Inventors: David Gaddy, Niklas Helmick, Jonathan E. Wilson, Jack Hale
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20250084038
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: May 15, 2024
    Publication date: March 13, 2025
    Inventors: Jonathan E. Wilson, James E. Audia, Jacob I. Stuckey
  • Modulators of TREX1
    Patent number: 12172990
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: December 24, 2024
    Assignee: Constellation Pharmaceuticals, Inc.
    Inventors: Anna Gardberg, Victor S. Gehling, Avinash Khanna, Julian R. Levell, Jonathan E. Wilson, Kennedy Taveras
  • MODULATORS OF TREX1
    Publication number: 20240262814
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 8, 2024
    Inventors: Julian R. Levell, Aaron Coffin, Avinash Khanna, Jonathan E. Wilson
  • MODULATORS OF TREX1
    Publication number: 20240246946
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: April 25, 2022
    Publication date: July 25, 2024
    Inventors: Julian R. Levell, Aaron Coffin, Mary-Margaret Zablocki, Jonathan E. Wilson, Avinash Khanna, David J. Guerin, William T. McElroy, Jennifer L. Rocnik
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20240239760
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: November 8, 2023
    Publication date: July 18, 2024
    Inventors: James E. Audia, Jonathan E. Wilson
  • Methods and apparatus for inverting a hollow sleeve and thereafter reverting an inverted hollow sleeve
    Patent number: 12022998
    Abstract: Apparatus for inverting an elongated flexible tubular sleeve having a proximal end, a distal end and a central lumen extending between the proximal end and the distal end, the apparatus comprising: a hollow tube comprising a proximal end, a distal end and a central lumen extending between the proximal end and the distal end; and an elongated rod movably disposed within the central lumen of the hollow tube, the elongated rod having a proximal end and a distal end, wherein the distal end of the elongated rod comprises a sleeve plug for securing a distal end of an elongated flexible tubular sleeve to the distal end of the hollow tube; wherein, when the elongated flexible tubular sleeve is disposed over the hollow tube, (i) the sleeve plug of the elongated rod is configured to be moved proximally to clamp the distal end of the elongated flexible tubular sleeve to the distal end of the hollow tube, and (ii) the sleeve plug of the elongated rod is configured to be moved distally to release the distal end of the elo
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: July 2, 2024
    Assignee: Lumendi Ltd.
    Inventors: David Gaddy, Niklas Helmick, Jonathan E. Wilson, Jack Hale
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20240166624
    Abstract: Provided are compounds of Formula (I): (I); and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: March 1, 2022
    Publication date: May 23, 2024
    Inventors: James E. Audia, Jacob I. Stuckey, Byron DeLaBarre, Jonathan E. Wilson
  • PPARG inverse agonists and uses thereof
    Patent number: 11820747
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Grant
    Filed: April 3, 2023
    Date of Patent: November 21, 2023
    Assignee: Flare Therapeutics Inc.
    Inventors: Jonathan E. Wilson, James E. Audia, Jacob I. Stuckey
  • PPARG INVERSE AGONISTS AND USES THEREOF
    Publication number: 20230331678
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with PPARG.
    Type: Application
    Filed: April 3, 2023
    Publication date: October 19, 2023
    Inventors: Jonathan E. Wilson, James E. Audia, Jacob I. Stuckey
  • SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1
    Publication number: 20230233541
    Abstract: Provided are compounds of Formula (I): (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: May 27, 2021
    Publication date: July 27, 2023
    Inventors: Mary-Margaret Zablocki, Kennedy Taveras, Jonathan E. Wilson, Aaron Coffin, Julian R. Levell, Aravind Prasad Medikonda
  • MODULATORS OF TREX1
    Publication number: 20230167070
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: April 30, 2021
    Publication date: June 1, 2023
    Inventors: Julian R. Levell, Jonathan E. Wilson, Aaron Coffin, Kennedy Taveras
  • Medical instruments for performing minimally-invasive procedures
    Patent number: 11504104
    Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a handle attached to the proximal end of the shaft; and an end effector attached to the distal end of the shaft; wherein the shaft comprises a flexible portion, a first articulating portion and a second articulating portion, wherein the flexible portion extends distally from the handle, the first articulating portion extends distally from the flexible portion, and the second articulating portion extends distally from the first articulating portion; wherein at least one articulation cable extends from the handle to the first articulating portion, such that when tension is applied to the at least one articulation cable, the first articulating portion deflects; wherein a plurality of articulation cables extend from the handle to the second articulating portion, such that when tension is applied to at least one of the plurality of articulation cables, the second articulating portion d
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: November 22, 2022
    Inventors: Amos Cruz, Jonathan O'Keefe, Niklas Helmick, Jonathan E. Wilson
  • COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS
    Publication number: 20220331304
    Abstract: Provided are methods for treating neurological disorders using compounds of Formula (I), and pharmaceutically acceptable salts and compositions thereof.
    Type: Application
    Filed: July 29, 2020
    Publication date: October 20, 2022
    Inventors: Francois Brucelle, Julian R. Levell, Jonathan E. Wilson
  • MODULATORS OF TREX1
    Publication number: 20220313701
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compostions thereof, which are useful for treating a variety of conditions associated with TREX1.
    Type: Application
    Filed: May 1, 2020
    Publication date: October 6, 2022
    Inventors: Avinash Khanna, Jonathan E. Wilson, Mary-Margaret Zablocki