Patents by Inventor Jonathan Ee-ren LIM

Jonathan Ee-ren LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210113555
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 22, 2021
    Applicant: IGNYTA, INC.
    Inventors: Gang Li, Ge Wei, Zachary D. Hornby, Jonathan Ee-ren Lim
  • Patent number: 10869864
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: December 22, 2020
    Assignee: IGNYTA, INC.
    Inventors: Gang Li, Ge Wei, Zachary D. Hornby, Jonathan Ee-ren Lim
  • Patent number: 10799503
    Abstract: Disclosed herein are methods of treating cancer in a subject, wherein the subject is known to possess at least one genetic alteration in RET, comprising administering to the subject a therapeutically effective amount of N-[3-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N?-[5-(2,2,2-trifluoro-1, 1-dimethylethyl)-3-isoxazolyl]-urea, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: October 13, 2020
    Assignee: IGNYTA, INC.
    Inventors: Jonathan Ee-Ren Lim, Pratik S. Multani, Richard Landin, Rupal Patel, Jennifer Wright Oliver
  • Publication number: 20200069688
    Abstract: Disclosed herein are methods of treating cancer in a subject, wherein the subject is known to possess at least one genetic alteration in RET, comprising administering to the subject a therapeutically effective amount of N-[3-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N?-[5-(2,2,2-trifluoro-1, 1-dimethylethyl)-3-isoxazolyl]-urea, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 5, 2020
    Applicant: IGNYTA, INC.
    Inventors: Jonathan Ee-Ren Lim, Pratik S. Multani, Richard Landin, Rupal A. Patel, Jennifer Wright Oliver
  • Publication number: 20190000840
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Application
    Filed: December 15, 2016
    Publication date: January 3, 2019
    Applicant: IGNYTA, INC.
    Inventors: Gang LI, Ge WEI, Zachary D. HORNBY, Jonathan Ee-ren LIM