Abstract: Methods for determining a variant frequency in a test sample from a subject, and methods for labeling sequencing reads as having or not having a variant are described herein. Exemplary methods include generating a reference match score and a variant match score by aligning sequencing reads to a corresponding variant sequence and a corresponding reference sequence, and labeling the sequencing read as having or not having the variant based on the determined match scores. Also described herein are methods monitoring disease progression and methods of treating a subject having a disease. Further described are devices and systems for implementing such methods.

Abstract: The present application is directed to systems and methods for transferring data between data backup sites. Backup data for transferring from a source data backup site to a destination data backup site is determined based on a storage parameter, the backup data comprising data associated with a client device. A transfer parameter is received from the destination data backup site, the transfer parameter comprising a storage logical site available for data storage. The determined backup data is matched to the storage logical site based on a parameter selected from a group consisting of the storage parameter, and the transfer parameter. A transfer of the determined backup data to the storage logical site is scheduled based on a parameter selected from a group consisting of the storage parameter, the transfer parameter, and a schedule parameter.

Abstract: The present application is directed to systems and methods for transferring data between data backup sites. A backup data transfer of data associated with a client device is scheduled, and backup data is transferred from a source data backup site to a destination data backup site. A backend process associated with the client device is suspended, and a determination is made as to whether all backup data for the client has transferred from the source backup data site to the destination backup data site. Responsive to the determination, the backend process associated with the client device is resumed.

Abstract: The present application is directed to systems and methods for transferring data between data backup sites. A backup data transfer of data associated with a client device is scheduled, and backup data is transferred from a source data backup site to a destination data backup site. A backend process associated with the client device is suspended, and a determination is made as to whether all backup data for the client has transferred from the source backup data site to the destination backup data site. Responsive to the determination, the backend process associated with the client device is resumed.

Abstract: The present application is directed to systems and methods for transferring data between data backup sites. Backup data for transferring from a source data backup site to a destination data backup site is determined based on a storage parameter, the backup data comprising data associated with a client device. A transfer parameter is received from the destination data backup site, the transfer parameter comprising a storage logical site available for data storage. The determined backup data is matched to the storage logical site based on a parameter selected from a group consisting of the storage parameter, and the transfer parameter. A transfer of the determined backup data to the storage logical site is scheduled based on a parameter selected from a group consisting of the storage parameter, the transfer parameter, and a schedule parameter.

Abstract: The data transfer between data backup sites techniques include a method, a system, and/or a computer software product. In some embodiments of these techniques, the method includes determining backup data for transferring from a source data backup site to a destination data backup site based on a storage parameter, the backup data comprising data associated with a client device. The method further includes receiving a transfer parameter from the destination data backup site, the transfer parameter comprising a storage logical site available for data storage. The method further includes matching the determined backup data to the storage logical site based on a parameter selected from a group consisting of the storage parameter, and the transfer parameter. The method further includes scheduling a transfer of the determined backup data to the storage logical site based on a parameter selected from a group consisting of the storage parameter, the transfer parameter, and a schedule parameter.

Abstract: The data transfer between data backup sites techniques include a method, a system, and/or a computer software product. In some embodiments of these techniques, the method includes determining backup data for transferring from a source data backup site to a destination data backup site based on a storage parameter, the backup data comprising data associated with a client device. The method further includes receiving a transfer parameter from the destination data backup site, the transfer parameter comprising a storage logical site available for data storage. The method further includes matching the determined backup data to the storage logical site based on a parameter selected from a group consisting of the storage parameter, and the transfer parameter. The method further includes scheduling a transfer of the determined backup data to the storage logical site based on a parameter selected from a group consisting of the storage parameter, the transfer parameter, and a schedule parameter.

Abstract: A method for the administration of a differential file backup system in a client-server system is disclosed in which the various component files that comprise a backup file are read from a first memory device of the file backup system to a second memory device and processed by the server. The server processes the various file components, or archive files in which the various file components reside, to reduce the number of access points across the first memory device to enhance the efficiency of the file retrieval, file reconstruction, and file restore operations of the backup file system.

Abstract: A method and apparatus for providing a multiple copy file backup system is disclosed in which files that have been previously backed up by a first user are to be backed up by different users. The first instance of backing up a file results in storing the file in a first location and associating the file and user in an entry in 238808-1a file data table. For other users needing to backup the same file, the contents of the file are copied from the first location into a second location within the file backup storage system. The file backup system creates two new entries in the file data table. In one entry the file stored in the second location is associated with a User-Pool that allows sharing the file contents among the users. The second and subsequent entries in the file data table will be created as subsequent users desiring desire to backup the file.

Abstract: A method for the administration of a differential file backup system in a client-server system is disclosed in which the various component files that comprise a backup file are read from a first memory device of the file backup system to a second memory device and processed by the server. The server processes the various file components, or archive files in which the various file components reside, to reduce the number of access points across the first memory device to enhance the efficiency of the file retrieval, file reconstruction, and file restore operations of the backup file system.