Patents by Inventor Jonathan F. Tait

Jonathan F. Tait has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of imaging cell death in vivo
    Patent number: 7666389
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: February 23, 2010
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, Peter D. Katsikis, H. William Strauss, Jonathan F. Tait
  • Method of imaging cell death in vivo
    Publication number: 20080138279
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Application
    Filed: November 15, 2007
    Publication date: June 12, 2008
    Applicants: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. William Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Method of imaging cell death in vivo
    Patent number: 7357915
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: April 15, 2008
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. W. Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Annexin derivatives with endogenous chelation sites
    Patent number: 7204972
    Abstract: Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X1-Gly-X2, where X1 and X2 are selected from Gly and Cys, where at least one of X1 or X2 is Cys. Radionuclides are readily chelated by the modified annexins to provide radiolabeled annexins useful in imaging vascular thrombi and apoptosis in vivo.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: April 17, 2007
    Assignee: University of Washington
    Inventors: Jonathan F. Tait, David S. Brown
  • Annexin derivatives with endogenous chelation sites
    Patent number: 6833448
    Abstract: Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X1-Gly-X2, where X1 and X2 are selected from Gly and Cys, where at least one of X1 or X2 is Cys. Radionuclides are readily chelated by the modified annexins to provide radiolabeled annexins useful in imaging vascular thrombi and apoptosis in vivo.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: December 21, 2004
    Assignee: University of Washington
    Inventors: Jonathan F. Tait, David S. Brown
  • Annexin derivatives with endogenous chelation sites
    Publication number: 20020103341
    Abstract: Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X1-Gly-X2, where X1 and X2 are selected from Gly and Cys, where at least one of X1 or X2 is Cys. Radionuclides are readily chelated by the modified annexins to provide radiolabeled annexins useful in imaging vascular thrombi and apoptosis in vivo.
    Type: Application
    Filed: October 3, 2001
    Publication date: August 1, 2002
    Applicant: University of Washington
    Inventors: Jonathan F. Tait, David S. Brown
  • Annexin derivative with endogenous chelation sites
    Patent number: 6323313
    Abstract: Modified annexins having an N-terminal chelation site comprising an amino acid extension are disclosed. The amino acid extension includes an amino acid sequence X1-Gly-X2, where X1 and X2 are selected from Gly and Cys, where at least one of X1 or X2 is Cys. Radionuclides are readily chelated by the modified annexins to provide radiolabeled annexins useful in imaging vascular thrombi and apoptosis in vivo.
    Type: Grant
    Filed: June 1, 1999
    Date of Patent: November 27, 2001
    Assignee: The University of Washington
    Inventors: Jonathan F. Tait, David S. Brown
  • Method of imaging cell death in vivo
    Patent number: 6197278
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: March 6, 2001
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. William Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Phospholipid-targeted thrombolytic agents
    Patent number: 5632986
    Abstract: Conjugates with an affinity for phospholipids are disclosed. The conjugates comprise a first compound having affinity for phospholipids, with a binding constant that is not greater than about 10.sup.-7 M and a second compound that lyses thrombi or is a precursor of a compound that lyses thrombi.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: May 27, 1997
    Assignee: The University of Washington
    Inventors: Jonathan F. Tait, Kazuo Fujikawa