Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.

Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: A low profile catheter system includes a catheter hub with proximal, distal, and intermediate portions, a stabilization surface located on an underside, and a receptacle located within a top surface. A substantially linear flow path extends from an opening at the distal portion to an inlet located within the intermediate portion and allows fluid to flow between the distal and intermediate portions. The inlet of the flow path is located between the proximal and distal portions. A base connector has a fluid path extending through at least a portion of the base connector and between a first opening located nearer a first end and a second opening. The fluid path is fluidly connected to the inlet of the flow path and a second end of the base connector is retained within the receptacle by the proximal portion when the base connector is received by the receptacle.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: A low profile catheter system includes a catheter hub with a stabilization surface that is located on an underside of the catheter hub and stabilizes the catheter hub on a patient. A substantially linear flow path extends from an opening at the distal end of the catheter hub to an inlet located within an intermediate portion of the catheter hub. The flow path allows fluid to flow between the distal end and the intermediate portion. The intermediate portion receives a base connector having a fluid path. The fluid path has a first opening and is fluidly connected to the inlet of the flow path in the catheter hub and a biasing member biases the first opening toward the inlet when the base connector is received by the intermediate portion.

Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.

Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.

Abstract: A low profile catheter system includes a catheter hub with a stabilization surface that is located on an underside of the catheter hub and stabilizes the catheter hub on a patient. A substantially linear flow path extends from an opening at the distal end of the catheter hub to an inlet located within an intermediate portion of the catheter hub. The flow path allows fluid to flow between the distal end and the intermediate portion. The intermediate portion receives a base connector having a fluid path. The fluid path has a first opening and is fluidly connected to the inlet of the flow path in the catheter hub and a biasing member biases the first opening toward the inlet when the base connector is received by the intermediate portion.

Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.

Abstract: A display system comprises a screen having a concave spherical surface positioned so as to be visible to a user of the system. The screen comprises a plurality of kite-shaped screen elements supported adjacent one another so as to form that spherical surface. Each of the screen elements comprises a respective faceplate comprising optical fibers extending adjacent each other so as to transmit light therethrough between two opposing face surfaces. One of the face surfaces is a concave spherical display image output surface, and the other of the face surfaces is a substantially planar image input surface. The screen elements also each comprise a respective image panel having a field of pixels each transmitting light corresponding to serial images of said panel. The fibers of the faceplate receive the light of the pixels of the image panel and together transmit the light from the image panel coherently to its image output surface so that the images of the panel are displayed on the image output surface.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal key, and a dose stop member engaging the dose set knob. Rotation of the dose set knob to set a medication dose causes rotation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal thread and an internal key proximate to a distal end of the internal thread, and a dose stop member comprising an external thread engaging the internal thread of the dose set knob. Rotation of the dose set knob to set a medication dose causes lateral translation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: A display system comprises a screen having a concave spherical surface positioned so as to be visible to a user of the system. The screen comprises a plurality of kite-shaped screen elements supported adjacent one another so as to form that spherical surface. Each of the screen elements comprises a respective faceplate comprising optical fibers extending adjacent each other so as to transmit light therethrough between two opposing face surfaces. One of the face surfaces is a concave spherical display image output surface, and the other of the face surfaces is a substantially planar image input surface. The screen elements also each comprise a respective image panel having a field of pixels each transmitting light corresponding to serial images of said panel. The fibers of the faceplate receive the light of the pixels of the image panel and together transmit the light from the image panel coherently to its image output surface so that the images of the panel are displayed on the image output surface.

Abstract: A medication injection pen, including a housing, a dose set knob (DSK) comprising an internal thread and an internal key proximate to a distal end of the internal thread, and a dose stop member comprising an external thread engaging the internal thread of the dose set knob. Rotation of the dose set knob to set a medication dose causes lateral translation of the dose stop member with respect to the dose set knob, and when the dose set knob is rotated to a last dose setting position, the dose stop member rotationally abuts the internal key thereby preventing further rotational movement of the dose set knob in a dose setting direction.

Abstract: A display system comprises a screen having a concave spherical surface positioned so as to be visible to a user of the system. The screen comprises a plurality of kite-shaped screen elements supported adjacent one another so as to form that spherical surface. Each of the screen elements comprises a respective faceplate comprising optical fibers extending adjacent each other so as to transmit light therethrough between two opposing face surfaces. One of the face surfaces is a concave spherical display image output surface, and the other of the face surfaces is a substantially planar image input surface. The screen elements also each comprise a respective image panel having a field of pixels each transmitting light corresponding to serial images of said panel. The fibers of the faceplate receive the light of the pixels of the image panel and together transmit the light from the image panel coherently to its image output surface so that the images of the panel are displayed on the image output surface.

Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from interventional procedures. The vessel wound closure system comprises at least a biocompatible, viscoelastic, self-sealing septum material injected onto the adventitia of the target vessel prior to performance of an interventional procedure. The prior injected septum material remains and seals the puncture wound of the target vessel even after various components associated with accessing the target vessel and the performance of the interventional procedure are removed from the target vessel and the puncture wound.

Abstract: An instrument for controlling bleeding includes an outer shaft, an intermediate shaft telescopically received within a central lumen of the outer shaft, and an inner shaft telescopically received within a central lumen of the intermediate shaft, the inner shaft having a proximal end and a distal end that extends distally from the intermediate shaft. The instrument includes a hemostat disposed at the distal end of the inner shaft, and a fluid-resistant element connected to the distal end of the outer shaft and surrounding the hemostat. The fluid-resistant element has a breakable, fluid-resistant seal at a distal end thereof that protects the hemostat from fluids until the hemostat is delivered and deployed onto tissue. In one embodiment, the instrument includes an inflatable balloon to deploy and tamponade the hemostat.

Abstract: An instrument for deploying hemostats has an intermediate shaft having a proximal end, a distal end, and a central lumen, and an inner shaft telescopically received within the central lumen of the intermediate shaft. The instrument includes an inflatable balloon, a first actuator for inflating the balloon, and a second actuator for moving the distal ends of the intermediate and inner shafts relative to one another for changing the shape of the inflated balloon. A proximal end of the balloon is secured to the distal end of the intermediate shaft and the distal end of the balloon is secured to the distal end of the inner shaft. The intermediate and inner shafts are moveable so that the inflated balloon has a toroidal shape and a flattened distal face. The inflated balloon has a major axis that is perpendicular to the longitudinal axis of the intermediate shaft.

Abstract: The present invention is directed to processes of making flowable hemostatic compositions and devices that include the flowable hemostatic composition disposed therein, where a volume of a biocompatible liquid, a volume of a biocompatible gas, and an amount of solid particles of a biocompatible polymer are mixed together to form a substantially homogenous composition including a discontinuous gas phase and the solid particles substantially homogenously dispersed throughout a continuous liquid phase to form a flowable hemostatic composition, and the composition then transferred into a device suitable for applying the flowable hemostatic composition to a site of a body requiring hemostasis under conditions effective to maintain the substantially homogeneous dispersion of the gas phase and the solid particles throughout the liquid phase, wherein said transfer of said substantially homogenous hemostatic composition is conducted at an angle.