Abstract: The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.

Abstract: A removable facial interface for a head-mountable device (HMD) is disclosed. In an example, an HMD includes a display; a facial interface frame at least partially surrounding the display; a removable facial interface attached to the facial interface frame; a first attachment mechanism attached to one of the facial interface frame or the removable facial interface; and a second attachment mechanism attached to the other of the facial interface frame or the removable facial interface, the removable facial interface being attached to the facial interface frame by the first attachment mechanism and the second attachment mechanism.

Abstract: An apparatus can include a display, a facial interface, and a connector between the display and the facial interface. The facial interface can at least translate or rotate relative to the display via the connector.

Abstract: The invention provided herein provides dosage and dosage regimens for N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine (Compound (1)), or a pharmaceutically acceptable salt thereof, Compound (1) for the treatment of PRC2-mediated diseases or disorders. In addition, the invention provides using such dosage and dosage regimens in methods for treating PRC2-mediated diseases or disorders.

Abstract: A system includes an asset management system in communication with an asset disposed within a rack, an asset tracking server, a gateway, and a set of equipment racks including the rack in which the asset is disposed. Each equipment rack defines a face. The equipment rack includes an observer device and a location indicator device. The system includes a set of tags attached to assets disposed within the set of equipment racks, a tag of the set of tags attached to the asset. The asset management system is to identify a maintenance event associated with the asset and is to communicate the identity of the asset to the asset tracking server. The asset tracking server is to locate the rack location of the tag associated with the asset and is to communicate with the associated observer device, which is to direct the location indicator device to provide a light signal.

Abstract: A system includes an asset management system in communication with an asset disposed within a rack, an asset tracking server, a gateway, and a set of equipment racks including the rack in which the asset is disposed. Each equipment rack defines a face. The equipment rack includes an observer device and a location indicator device. The system includes a set of tags attached to assets disposed within the set of equipment racks, a tag of the set of tags attached to the asset. The asset management system is to identify a maintenance event associated with the asset and is to communicate the identity of the asset to the asset tracking server. The asset tracking server is to locate the rack location of the tag associated with the asset and is to communicate with the associated observer device, which is to direct the location indicator device to provide a light signal.

Abstract: A system includes an asset management system in communication with an asset disposed within a rack, an asset tracking server, a gateway, and a set of equipment racks including the rack in which the asset is disposed. Each equipment rack defines a face. The equipment rack includes an observer device and a location indicator device. The system includes a set of tags attached to assets disposed within the set of equipment racks, a tag of the set of tags attached to the asset. The asset management system is to identify a maintenance event associated with the asset and is to communicate the identity of the asset to the asset tracking server. The asset tracking server is to locate the rack location of the tag associated with the asset and is to communicate with the associated observer device, which is to direct the location indicator device to provide a light signal.

Abstract: The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.

Abstract: A system includes an asset management system in communication with an asset disposed within a rack, an asset tracking server, a gateway, and a set of equipment racks including the rack in which the asset is disposed. Each equipment rack defines a face. The equipment rack includes an observer device and a location indicator device. The system includes a set of tags attached to assets disposed within the set of equipment racks, a tag of the set of tags attached to the asset. The asset management system is to identify a maintenance event associated with the asset and is to communicate the identity of the asset to the asset tracking server. The asset tracking server is to locate the rack location of the tag associated with the asset and is to communicate with the associated observer device, which is to direct the location identification device to provide a light signal.

Abstract: A wearable device is adapted to monitor a wearer's physical activity patterns and to provide assistance to the wearer when a need for assistance is indicated. The device includes a processor is programmed to cause the device to collect activity data necessary to determine the physical activity pattern of the wearer over time, to provide the gathered activity data to a server via a network interface for processing to create or update behavioral rules for the wearer, to receive the behavioral rules from the server for comparison to the received activity data, and to provide to the wearer via the user interface assistance information when the wearer has requested assistance or when a check of the wearer's activity against the behavioral rules indicates that the wearer may need assistance.

Abstract: Embodiments are directed to devices, systems, and methods for monitoring and assisting a subject in various life tasks.

Abstract: A device for irrigating soil has a chassis having wheels or tracks for motion, the chassis having one or more water sprinklers with streams directed at the soil, a water storage tank, and a sloped catchment surface having one or more sloped planes or curved surfaces for receiving water from a refill station into the water storage tank, wherein, under the control of an electronic circuit, the irrigation device can refill the water tank by positioning any part of the catchment surface under a water stream from the refill station. A method has the steps of measuring soil moisture at remote locations, refilling the mobile robot using a gravity feed water stream, defining a route for distribution of water, traversing the irrigation routes, refilling water according to soil moisture measurements, storing photovoltaic energy in a battery, and rotating, to a compass heading such that the photovoltaic array is optimally oriented.

Abstract: Data indexing using polyarchical indexing codes and automatically generated expansion paths. For a piece of data, an indexing code is received relating to a particular categorization or other indexing parameter. Based upon the indexing code, one or more expansion sets of codes are retrieved and applied to the piece of data. The expansion sets of codes may include indexing codes that relate to hierarchical levels of indexing. The expansion sets of codes may also include different expansion paths through the hierarchical levels of indexing. The polyarchical codes may include multiple cross-categorization of the data across the same or different levels of categories. They may also include multiple expansion paths in different directions across hierarchical levels of categories or indexing.

Abstract: Data indexing using polyarchical indexing codes and automatically generated expansion paths. For a piece of data, an indexing code is received relating to a particular categorization or other indexing parameter. Based upon the indexing code, one or more expansion sets of codes are retrieved and applied to the piece of data. The expansion sets of codes may include indexing codes that relate to hierarchical levels of indexing. The expansion sets of codes may also include different expansion paths through the hierarchical levels of indexing. The polyarchical codes may include multiple cross-categorization of the data across the same or different levels of categories. They may also include multiple expansion paths in different directions across hierarchical levels of categories or indexing.

Abstract: Data indexing using polyarchical indexing codes and automatically generated expansion paths. For a piece of data, an indexing code is received relating to a particular categorization or other indexing parameter. Based upon the indexing code, one or more expansion sets of codes are retrieved and applied to the piece of data. The expansion sets of codes may include indexing codes that relate to hierarchical levels of indexing. The expansion sets of codes may also include different expansion paths through the hierarchical levels of indexing. The polyarchical codes may include multiple cross-categorization of the data across the same or different levels of categories. They may also include multiple expansion paths in different directions across hierarchical levels of categories or indexing.

Abstract: Data indexing using polyarchical indexing codes and automatically generated expansion paths. For a piece of data, an indexing code is received relating to a particular categorization or other indexing parameter. Based upon the indexing code, one or more expansion sets of codes are retrieved and applied to the piece of data. The expansion sets of codes may include indexing codes that relate to hierarchical levels of indexing. The expansion sets of codes may also include different expansion paths through the hierarchical levels of indexing. The polyarchical codes may include multiple cross-categorization of the data across the same or different levels of categories. They may also include multiple expansion paths in different directions across hierarchical levels of categories or indexing.

Abstract: Data indexing using polyarchical indexing codes and automatically generated expansion paths. For a piece of data, an indexing code is received relating to a particular categorization or other indexing parameter. Based upon the indexing code, one or more expansion sets of codes are retrieved and applied to the piece of data. The expansion sets of codes may include indexing codes that relate to hierarchical levels of indexing. The expansion sets of codes may also include different expansion paths through the hierarchical levels of indexing. The polyarchical codes may include multiple cross-categorization of the data across the same or different levels of categories. They may also include multiple expansion paths in different directions across hierarchical levels of categories or indexing.

Abstract: The invention provides a process for preparing an enantiomerically enriched cis-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one by reacting a sulphonic ester of &bgr;,&bgr;-dimethyl-&ggr;-(hydroxymethyl)-&ggr;-butyrolactone with a compound of formula M(C1-6 alkoxide)y.

Abstract: A process for the preparation of cis-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one which comprises either: 1) reacting a sulphonic ester of &bgr;,&bgr;-dimethyl-&ggr;-(hydroxymethyl)-&ggr;-butyrolactone with a compound of formula M(C1-6 alkoxide)y, in a suitable solvent; or 2) reacting a C1-4 alkyl ester of 4,5-epoxy-3,3-dimethylpentanoic acid with M(C1-6 alkoxide)y, in a suitable solvent; wherein M is a suitable cation and y fulfills valency requirements.