Patents by Inventor Jonathan H. Lass

Jonathan H. Lass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12062178
    Abstract: Embodiments discussed herein facilitate automated and/or semi-automated segmentation of endothelial cells via a trained deep learning model. One example embodiment is a method, comprising: accessing an optical microscopy image comprising a set of corneal endothelial cells of a patient of a keratoplasty; pre-processing the optical microscopy image to generate a pre-processed optical microscopy image via correcting for at least one of shading or illumination artifacts in the optical microscopy image; segmenting, based at least in part on a trained deep learning (DL) model, a plurality of corneal endothelial cells of the set of corneal endothelial cells in the pre-processed optical microscopy image; and displaying, via a graphical user interface (GUI), at least the segmented plurality of corneal endothelial cells.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: August 13, 2024
    Assignee: Case Western Reserve University
    Inventors: David L. Wilson, Naomi Joseph, Jonathan H. Lass, Beth Ann Benetz, Harry J. Menegay, Elizabeth Fitzpatrick
  • Publication number: 20210278655
    Abstract: Embodiments discussed herein facilitate automated and/or semi-automated segmentation of endothelial cells via a trained deep learning model. One example embodiment is a method, comprising: accessing an optical microscopy image comprising a set of corneal endothelial cells of a patient of a keratoplasty; pre-processing the optical microscopy image to generate a pre-processed optical microscopy image via correcting for at least one of shading or illumination artifacts in the optical microscopy image; segmenting, based at least in part on a trained deep learning (DL) model, a plurality of corneal endothelial cells of the set of corneal endothelial cells in the pre-processed optical microscopy image; and displaying, via a graphical user interface (GUI), at least the segmented plurality of corneal endothelial cells.
    Type: Application
    Filed: January 5, 2021
    Publication date: September 9, 2021
    Inventors: David L. Wilson, Naomi Joseph, Jonathan H. Lass, Beth Ann Benetz, Harry J. Menegay, Elizabeth Fitzpatrick