Abstract: The present disclosure relates to a coating composition, in particular a cool roof or solar reflective coating composition, which comprises an organosilane-functionalised colloidal silica and hollow microspheres, wherein the organosilane-functionalised colloidal silica comprises silica particles with one or more organosilane moieties bound to their surface, and wherein the hollow microspheres comprise a polymeric shell. The present disclosure also relates to substrate coated with the coating composition, and to a method for making such a coating composition.

Abstract: A component for a turbine engine may be formed by spraying particulate with a nozzle toward a substrate. The particulate may be deposited to form one or more annular layers and a reinforcing structure. The component may be a closed loop annular component having a reinforcing structure of specific dimensions enabled by the methods described.

Abstract: Disclosed herein are nucleic acid molecules, polypeptides, cells, vectors, and pharmaceutical compositions relating to miniaturized dystrophin. Methods of production and methods of therapeutic use of the miniaturized dystrophin are also disclosed.

Abstract: A component for a turbine engine may be formed by spraying particulate with a nozzle toward a substrate. The particulate may be deposited to form one or more annular layers and a reinforcing structure. The component may be a closed loop annular component having a reinforcing structure of specific dimensions enabled by the methods described.

Abstract: The invention provides apparatus for mounting a furniture unit to a wall and, in particular, to wall studs. The apparatus includes sliding fixings that allow the spacing between fixing members to be adjusted and, thereby, allow the horizontal position of the furniture unit to adjusted to any desired position relative to the wall studs.

Abstract: A grab rail has an elongate shaft and attachment fittings to attach the shaft to a wall. The attachment fittings are configured with at least two connections that are selectively engageable with the elongate shaft to enable the spacing between contact surfaces on the attachment fittings to be varied.

Abstract: A method and apparatus for mounting a toilet seat hinge to a toilet pan uses an adhesive. The adhesivised surface of the hinge is held clear of the pan until correct positioning is established. Thereafter the adhesivised surface is displaced directly into contact with the pan.

Abstract: Examples described herein generally relate to rendering grid-aligned digital ink on a display of a computing device. In an example, the computing device determines grid pattern data associated with a grid pattern displayed on the display and a velocity of the input. Based the grid line pattern data and the velocity, the computing device may render digital ink that is traced along one or more grid lines of the grid pattern.

Abstract: Disclosed herein are nucleic acid molecules, polypeptides, cells, vectors, and pharmaceutical compositions relating to miniaturized dystrophin. Methods of production and methods of therapeutic use of the miniaturized dystrophin are also disclosed.

Abstract: Heterodimerizing domains with orthogonal mutations that drive heterodimerization, in particular heterodimerizing antibody CH3 domains, heterodimeric polypeptides comprising such heterodimerizing domains, and antibody constructs comprising such heterodimeric polypeptides, are provided.

Abstract: A component for a turbine engine may be formed by spraying particulate with a nozzle toward a substrate. The particulate may be deposited to form one or more annular layers and a reinforcing structure. The component may be a closed loop annular component having a reinforcing structure of specific dimensions enabled by the methods described.

Abstract: Disclosed herein are fusion proteins comprising: (a) a first polypeptide comprising Interleukin-2 (IL2); and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL2R?), wherein IL2 or IL2R? comprises at least one fewer glycosylation site compared to native IL2 or native IL2R?. Methods of production and methods of therapeutic use of the fusion proteins are also disclosed.

Abstract: The invention provides apparatus for mounting a furniture unit to a wall and, in particular, to wall studs. The apparatus includes sliding fixings that allow the spacing between fixing members to be adjusted and, thereby, allow the horizontal position of the furniture unit to adjusted to any desired position relative to the wall studs.

Abstract: A grab rail has an elongate shaft and attachment fittings to attach the shaft to a wall. The attachment fittings are configured with at least two connections that are selectively engageable with the elongate shaft to enable the spacing between contact surfaces on the attachment fittings to be varied.

Abstract: Disclosed herein are fusion proteins comprising: (a) a first polypeptide comprising Interleukin-2 (IL2); and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL2R?), wherein IL2 or IL2R? comprises at least one fewer glycosylation site compared to native IL2 or native IL2R?. Methods of production and methods of therapeutic use of the fusion proteins are also disclosed.

Abstract: A method is provided for mounting an item of furniture, and in particular a cabinet, in a cavity formed in wall cladding. The arrangement is such that part of the item of furniture is held against an outer surface of the cladding by fixing elements that are displaced into engagement with an inner face of the wall cladding. The fixing elements are displaced into position from the interior of the cabinet.

Abstract: Disclosed herein are nucleic acid molecules, polypeptides, cells, vectors, and pharmaceutical compositions relating to miniaturized dystrophin. Methods of production and methods of therapeutic use of the miniaturized dystrophin are also disclosed.

Abstract: Disclosed herein are nucleic acid molecules, polypeptides, cells, vectors, and pharmaceutical compositions relating to miniaturized dystrophin. Methods of production and methods of therapeutic use of the miniaturized dystrophin are also disclosed.

Abstract: A method and apparatus for mounting a toilet seat hinge to a toilet pan uses an adhesive. The adhesivised surface of the hinge is held clear of the pan until correct positioning is established. Thereafter the adhesivised surface is displaced directly into contact with the pan.

Abstract: Disclosed herein are fusion proteins comprising: (a) a first polypeptide comprising Interleukin-2 (IL2); and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL2R?), wherein IL2 or IL2R? comprises at least one fewer glycosylation site compared to native IL2 or native IL2R?. Methods of production and methods of therapeutic use of the fusion proteins are also disclosed.