Patents by Inventor Jonathan Heddle

Jonathan Heddle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250084407
    Abstract: It has been disclosed a method for the construction of single stranded DNA catenanes at the kilobase length scale, which can be used for the assembling scaffolds of covalently connected DNA origamis.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 13, 2025
    Applicant: Uniwersytet Jagiellonski
    Inventors: Jonathan HEDDLE, Yusuke SAKAI, Gerrit WILKENS
  • Publication number: 20240181077
    Abstract: The present invention provides an artificial TRAP-cage comprising a selected number of TRAP rings and encapsulated therein a guest cargo.
    Type: Application
    Filed: February 24, 2022
    Publication date: June 6, 2024
    Inventors: Jonathan HEDDLE, Artur BIELA, Yusuke AZUMA, Antonina NASKALSKA, Kinga BORZECKA-SOLARZ, Jan ROZYCKI, Izabela STUPKA
  • Publication number: 20240139339
    Abstract: The present invention provides an artificial TRAP-cage decorated with particular molecules (proteins, peptides, small molecules, nucleic acids) on the exterior.
    Type: Application
    Filed: February 24, 2022
    Publication date: May 2, 2024
    Inventors: Jonathan HEDDLE, Yusuke AZUMA, Antonina NASKALSKA, Kinga BORZECKA-SOLARZ, Jan ROZYCKI, Szymon GAWEL
  • Publication number: 20240122868
    Abstract: The present invention provides an artificial TRAP-cage comprising a selected number of TRAP rings which are held in place by cross-linkers, wherein the cross-linkers are selected for their specific characteristics whereby the cages are programmable to be opened or remain closed on demand, under specific conditions.
    Type: Application
    Filed: February 24, 2022
    Publication date: April 18, 2024
    Inventors: Jonathan HEDDLE, Artur BIELA, Yusuke AZUMA, Izabela STUPKA, Karolina MAJSTERKIEWICZ
  • Publication number: 20210403503
    Abstract: The subject matter of the invention is a method for conjugation of free thiol group(s) containing biomolecules, leading to the biomolecular complex formation, comprising a reaction to connect biomolecules using a gold-donor agent in which a —S—Au—S— bond is formed, characterised in that a gold-donor agent is halogen(triarylphosphine)gold (I). The subject matter of the invention is also the use of halogen(triarylphosphine)gold (I) molecules as the gold-donor agent in the method of biomolecular complex formation.
    Type: Application
    Filed: August 16, 2018
    Publication date: December 30, 2021
    Inventors: Jonathan HEDDLE, Ali MALAY
  • Publication number: 20070042485
    Abstract: The present invention provides a modified TRAP protein formed from a plurality of genetically engineered fusion molecules of TRAP monomers, wherein said fusion molecule consists of two, three or four wild type TRAP monomer equivalents.
    Type: Application
    Filed: June 15, 2006
    Publication date: February 22, 2007
    Inventors: Jonathan Heddle, Jeremy Tame