Abstract: The present disclosure is directed to a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method may include providing an intravascular device having a distal portion and a longitudinal axis and inserting the intravascular device into the vascular lumen. The method may further include positioning the distal portion in the vascular wall, rotating the intravascular device about the longitudinal axis, and advancing the intravascular device within the vascular wall.

Abstract: A piston monitoring assembly includes a magnetic body coupled to a piston that is configured to move in opposite directions during a piston stroke to dispense a fluid, a magnetic sensor configured to output signals representative of a magnetic field generated by the magnetic body, and a controller configured to examine the signals output by the magnetic sensor and to determine whether the piston is moving far enough to ensure that the fluid is being dispensed during a first movement of the piston in the piston stroke and that the fluid is prevented from being dispensed during a second movement of the piston in the piston stroke.

Abstract: Improved cold seal packaging rollers for packaging machines, as disclosed herein, may be configured to define a turned-up or bend along each edge portion of a packaging created by the packaging machine for avoiding jams of the packaging in automated packing systems. The improved cold seal packaging rollers may be incorporated directly into the cold seal packaging machine, replacing the standard rollers, or external to the machine to manipulate a completed packaging. The improved cold seal packaging rollers may comprise a first gear and a second gear, each having a circumferential toothed portion and a circumferential beveled portion. The circumferential beveled portion of the first gear may be angled inwardly toward a central axis as it moves away from the circumferential toothed portion. The circumferential beveled portion of the second gear may be angled outwardly away from a central axis as it moves away from the circumferential toothed portion.

Abstract: A method comprising performing simulations to determine energy transfer between the bulk fluid motion of gases through a combustion chamber and resonant acoustic modes of the combustion chamber using a simulation model. The method also comprises configuring one or more combustion chamber parameters for the simulation model to shape the resonant acoustic modes to diminish coupling between the resonant acoustic modes and driving mechanisms at a head portion of the combustion chamber and to enhance coupling between the resonant acoustic modes and damping mechanisms at an aft portion of the combustion chamber. The method further comprises determining whether the combustion chamber meets a predetermined performance level in response to determining that the combustion chamber meets a predetermined combustion stability level.

Abstract: Disclosed are methods and compositions for treating CTNNB1 syndrome. The disclosed methods and compositions may utilize or comprise a glycogen synthase kinase 3 (GSK3) inhibitor, or a pharmaceutically acceptable salt thereof. The GSK3 inhibitor may comprise small molecules such as substituted tricyclic pyrazolo-tetrahydroquinolinones, and the GSK3 inhibitor may selectively inhibit GSK3? and GSK3? or dually inhibit GSK3? and GSK3?.

Abstract: The present disclosure is directed to a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method may include providing an intravascular device having a distal portion and a longitudinal axis and inserting the intravascular device into the vascular lumen. The method may further include positioning the distal portion in the vascular wall, rotating the intravascular device about the longitudinal axis, and advancing the intravascular device within the vascular wall.

Abstract: The present disclosure provides world-controlled augments and application-controlled augments. World-controlled augments can be controlled directly by a shell in the artificial reality environment. To allow even inexperienced users to develop world-controlled augments, a world-controlled builder system is provided. Application-controlled augments may be resource intensive (e.g., using eye-tracking, social-media tie-ins, etc.), may support complicated interactions among themselves, may require or have extensive use of inputs and permissioned resources, and are controlled by their hosting application. When a running application is halted, the application closes its application-controlled augments but can choose to have the XR system run a “place-holder” world-controlled augment for as long as the application is not running. The place-holder world-controlled augment preserves the appearance of the application in the artificial reality environment but uses few system resources.

Abstract: A piston monitoring assembly includes a magnetic body coupled to a piston that is configured to move in opposite directions during a piston stroke to dispense a fluid, a magnetic sensor configured to output signals representative of a magnetic field generated by the magnetic body, and a controller configured to examine the signals output by the magnetic sensor and to determine whether the piston is moving far enough to ensure that the fluid is being dispensed during a first movement of the piston in the piston stroke and that the fluid is prevented from being dispensed during a second movement of the piston in the piston stroke.

Abstract: A feature extractor and novel training objective are provided for content-based image retrieval. For example, a computer-implemented method includes applying a query image and a search image to a neural network of a feature extraction network of a computing device, the query image indicating an object to be searched for in the search image. The feature extraction network includes the neural network, a spatial feature neural network receiving a first output of the neural network pertaining to the search image, and an embedding network receiving a second output of the neural network pertaining to the query image. The method includes generating spatial search features from the spatial feature neural network, generating a query feature from the embedding network, applying the query feature to an artificial neural network (ANN) index, and determining an optimal matching result of an object in the search image based on an operation using the ANN index.

Abstract: A sanitation device for cleaning a body of water in an immersion pool of a mikvah has a housing, a driving member and a bypass passageway. The housing includes an inlet, an outlet and internal liquid passages that communicate between the inlet and outlet. The driving member is arranged to urge flow of liquid through the internal liquid passages by exerting thrust upon liquid flowing through the driving member, wherein at least part of the liquid flowing through the liquid passages bypasses flowing through the driving member by flowing through the bypass passageway towards the device's outlet.

Abstract: Embodiments are directed to monitoring network traffic using network monitoring computers (NMCs). Metrics may be determined based on monitoring network traffic associated with a plurality of entities each associated with a profile that includes the metrics for each entity. Beaconing metrics associated with beaconing activity may be determined based on the metrics. The profile of each entity may be compared with the beaconing metrics to determine the entities that may be engaged in beaconing activity. The entities may be characterized based on beaconing activity such that the beaconing activity includes communication with endpoints associated with the third parties, employing communication protocols associated with the third-parties, or exchanging payloads consistent with the beaconing activity. Reports that include information associated with the entities and its beaconing activity may be generated.

Abstract: A method of predicting the long-term hedonic response to at least one predetermined sensory stimulus for an individual is disclosed. The method comprises the steps of (a) exposing the individual to the at least one sensory stimulus for a number of times over an initial time period of exposure according to an exposure pattern, (b) for each exposure, obtaining data indicative of the individual's hedonic response to the at least one sensory stimulus, (c) providing the data indicative of the individual's hedonic response and the exposure pattern to a machine learning algorithm, and (d) predicting the individual's long-term hedonic response to the sensory stimulus by the machine learning algorithm for a time point a predetermined prediction time period after the initial time period of exposure.

Abstract: A sanitation device for cleaning a body of water in an immersion pool of a mikvah has a hollow member that extends along an axis X. In an operative position suitable for cleaning the device is arranged to extend generally immersed in the water and in a general upright orientation. The device further has an upper opening that in the operative position is arranged to be generally flush with the upper surface of the water and a propeller arranged to rotate about axis X and located at a lower region of the device that is arranged to form a downward flow that urges water to enter the device via the upper opening of the device.

Abstract: Embodiments are directed to monitoring network traffic using network monitoring computers (NMCs). Metrics may be determined based on monitoring network traffic associated with a plurality of entities each associated with a profile that includes the metrics for each entity. Beaconing metrics associated with beaconing activity may be determined based on the metrics. The profile of each entity may be compared with the beaconing metrics to determine the entities that may be engaged in beaconing activity. The entities may be characterized based on beaconing activity such that the beaconing activity includes communication with endpoints associated with the third parties, employing communication protocols associated with the third-parties, or exchanging payloads consistent with the beaconing activity. Reports that include information associated with the entities and its beaconing activity may be generated.

Abstract: A generator (100, 101, 102, 103, 104, 105, 106, 107, 108, 109) is used for producing a treated oxygen containing gas for treating a body of matter (11). The generator (100, 101, 102, 103, 104, 105, 106, 107, 108, 109) extends along a generator axis and has an axially extending hollow sleeve (12) defining an internal space (14). At least one lid (16) is located at one of the axial ends of the sleeve (12) and a UV light source (18) and at least one magnet (20) are located along the axis.

Abstract: Systems, methods, and apparatuses are provided herein for implementing a PoE system comprising a plurality of power sourcing equipment that power a single powered device. Control circuitry may determine the power necessary to operate a powered device in a first power mode, and may cause the powered device to draw, from a first power sourcing device, to a first port of the powered device, a first wattage. The powered device may draw, from a second power sourcing device, to a second port of a powered device, a second wattage, where a sum of the first and second wattage equals the amount of power necessary to operate in the first power mode, wherein a first isolation boundary isolates the first power sourcing equipment, the first Ethernet link, and the first port, and wherein a second isolation boundary isolates the second power sourcing equipment, the second Ethernet link, and the second port.

Abstract: Techniques performed by a data processing system for operating a personalized oncology system herein include accessing a first histopathological image of a histopathological slide of a sample taken from a first patient; analyzing the first histopathological image using a first machine learning model configured to extract first features from the first histopathological image; searching a histological database that includes a plurality of second histopathological images and corresponding clinical data for a plurality of second patients to generate search results; analyzing the plurality of third histopathological images and the corresponding clinical data associated with the plurality of third histopathological images using statistical analysis techniques to generate associated statistics and metrics associated with mortality, morbidity, time-to-event, or a combination thereof for the plurality of third patients associated with the third histopathological images; and presenting an interactive visual representat

Abstract: A sanitation device for cleaning a body of water in an immersion pool of a mikvah has a hollow member that extends along an axis X. In an operative position suitable for cleaning the device is arranged to extend generally immersed in the water and in a general upright orientation. The device further has an upper opening that in the operative position is arranged to be generally flush with the upper surface of the water and a propeller arranged to rotate about axis X and located at a lower region of the device that is arranged to form a downward flow that urges water to enter the device via the upper opening of the device.

Abstract: The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.

Abstract: A generator (100, 101, 102, 103, 104, 105, 106, 107, 108, 109) is used for producing a treated oxygen containing gas for treating a body of matter (11). The generator (100, 101, 102, 103, 104, 105, 106, 107, 108, 109) extends along a generator axis and has an axially extending hollow sleeve (12) defining an internal space (14). At least one lid (16) is located at one of the axial ends of the sleeve (12) and a UV light source (18) and at least one magnet (20) are located along the axis.