Patents by Inventor Jonathan JACOBS

Jonathan JACOBS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE
    Publication number: 20170000785
    Abstract: The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
    Type: Application
    Filed: July 13, 2016
    Publication date: January 5, 2017
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: JONATHAN JACOB SABBAGH, CHAD DICKEY
  • Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use
    Patent number: 9399039
    Abstract: The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: July 26, 2016
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Jonathan Jacob Sabbagh, Chad Dickey
  • RECOMBINANT POLYPEPTIDE PRODUCTION
    Publication number: 20160024502
    Abstract: Disclosed herein is a method for producing a recombinant polypeptide in a mammalian cell culture in which the mammalian cells have a modified microRNA activity level. In one embodiment, a microRNA activity level is increased. In another embodiment, a microRNA activity level is decreased. In a more particular embodiment, the mammalian cells have a reduced miRNA-let-7a activity level.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Applicant: Medlmmune, LLC
    Inventors: Katie STREICHER, Jonathan JACOBS, Robert W. GEORGANTAS, III, Lydia GREENLEES, Koustubh RANADE, Michael BOWEN