Patents by Inventor Jonathan James Loughrey

Jonathan James Loughrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION
    Publication number: 20230357322
    Abstract: The present invention relates to crystalline forms of carbetocin, a method of their manufacture, and pharmaceutical compositions thereof.
    Type: Application
    Filed: May 2, 2023
    Publication date: November 9, 2023
    Applicant: Ferring B.V.
    Inventors: Elizabeth Serrano CHAVEZ, Helen SJOEGREN, Jette BOLL, Hayley REECE, Jonathan James LOUGHREY
  • Crystalline forms of a selective c-kit kinase inhibitor
    Patent number: 11767319
    Abstract: The present disclosure relates generally to various forms and compositions of N-(5-(5-((1R,2S)-2-fluorocyclopropyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide useful as a selective inhibitor of c-kit kinase and uses of the same in the treatment of c-kit kinase associated diseases.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: September 26, 2023
    Assignee: Third Harmonic Bio, Inc.
    Inventors: Gregg F. Keaney, Leonard Walter Rozamus, Jr., Jonathan James Loughrey, Jaclyn Raeburn, Yuxiang Song
  • ORGANIC ACID ADDITION SALTS OF S-PINDOLOL
    Publication number: 20230190706
    Abstract: The invention relates to a pharmaceutically acceptable acid addition salt of: (i) S-pindolol; and (ii) an organic acid, wherein the organic acid has: a pKal of greater than or equal to 2.5; and a chemical formula of CxHy(CO2H)z, where x is from 1 to 10, y is from 2 to 20 and z is 1 or 2. The pharmaceutically acceptable acid addition salt is useful in treating conditions such as cachexia, sarcopenia, a neuromuscular disorder and muscle weakness.
    Type: Application
    Filed: March 31, 2021
    Publication date: June 22, 2023
    Inventors: Robin Chandra BHATTACHERJEE, Andrew Justin Stewart COATS, Elaine MORTEN, Ronnie Maxwell LAWRENCE, Jaclyn RAEBURN, Kiara Marissa LOBATO, Jonathan James LOUGHREY
  • Method of manufacturing a pharmaceutical composition
    Patent number: 11673918
    Abstract: The present invention relates to crystalline forms of carbetocin, a method of their manufacture, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: June 13, 2023
    Assignee: FERRING B.V.
    Inventors: Elizabeth Serrano Chavez, Helen Sjoegren, Jette Boll, Hayley Reece, Jonathan James Loughrey
  • CRYSTALLINE FORMS OF A SELECTIVE C-KIT KINASE INHIBITOR
    Publication number: 20220056026
    Abstract: The present disclosure relates generally to various forms and compositions of N-(5-(5-((1R,2S)-2-fluorocyclopropyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide useful as a selective inhibitor of c-kit kinase and uses of the same in the treatment of c-kit kinase associated diseases.
    Type: Application
    Filed: July 15, 2021
    Publication date: February 24, 2022
    Applicant: Third Harmonic Bio, Inc.
    Inventors: Gregg F. Keaney, Leonard Walter Rozamus, JR., Jonathan James Loughrey, Jaclyn Raeburn, Yuxiang Song
  • POLYMORPHIC COMPOUNDS AND USES THEREOF
    Publication number: 20210393612
    Abstract: The present invention relates to free-base and salt forms, and compositions thereof of small molecule therapeutics acting as a scavenger for toxic aldehydes. The present invention further relates to use of the free-base and salt forms, and compositions thereof for treating diseases, disorders, or conditions in which aldehyde toxicity is implicated in their pathogenesis.
    Type: Application
    Filed: May 28, 2021
    Publication date: December 23, 2021
    Inventors: Stephen Gitu MACHATHA, Charles MONTGOMERY, Steven KRAUSERT, Jonathan James LOUGHREY, Hannah Ruth MCLACHLAN, Gregor SNEDDON
  • METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION
    Publication number: 20210309699
    Abstract: The present invention relates to crystalline forms of carbetocin, a method of their manufacture, and pharmaceutical compositions thereof.
    Type: Application
    Filed: April 15, 2021
    Publication date: October 7, 2021
    Applicant: FERRING B.V.
    Inventors: Elizabeth Serrano CHAVEZ, Helen SJOERGREN, Jette BOLL, Hayley REECE, Jonathan James LOUGHREY
  • TYK2 inhibitors, uses, and methods for production thereof
    Patent number: 11040967
    Abstract: The present invention provides compounds of formula I useful as inhibitors of Tyrosine Kinase 2 (Tyk2) solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: June 22, 2021
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Craig E. Masse, Jon P. Lawson, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • Method of manufacturing a pharmaceutical composition
    Patent number: 10981955
    Abstract: The present invention relates to crystalline forms of carbetocin, a method of their manufacture, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: April 20, 2021
    Assignee: FERRING B.V.
    Inventors: Elizabeth Serrano Chavez, Helen Sjoergren, Jette Boll, Hayley Reece, Jonathan James Loughrey
  • METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION
    Publication number: 20200216500
    Abstract: The present invention relates to crystalline forms of carbetocin, a method of their manufacture, and pharmaceutical compositions thereof.
    Type: Application
    Filed: August 10, 2018
    Publication date: July 9, 2020
    Applicant: FERRING B.V.
    Inventors: Elizabeth Serrano CHAVEZ, Helen SJOERGREN, Jette BOLL, Hayley REECE, Jonathan James LOUGHREY
  • TYK2 INHIBITORS, USES, AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20190337941
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 7, 2019
    Inventors: Jeremy Robert Greenwood, Craig E. Masse, Jon P. Lawson, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • TYK2 inhibitors, uses, and methods for production thereof
    Patent number: 10336752
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: July 2, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Jon P. Lawson, Craig E. Masse, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • TYK2 INHIBITORS, USES, AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20180258086
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 13, 2018
    Inventors: Jeremy Robert Greenwood, Craig E. Masse, Jon P. Lawson, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey