Patents by Inventor Jonathan K. Chambers

Jonathan K. Chambers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide sequences of human EDG-1c
    Publication number: 20030082743
    Abstract: Human EDG-1c polypeptidees and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Human EDG-1c is identified as a selective receptor for sphingosine-1-phosphate (“S-1-P”) and for di-hydro S-1-P.
    Type: Application
    Filed: January 12, 2001
    Publication date: May 1, 2003
    Inventors: Derk J. Bergsma, Winnie Chan, Jonathan K. Chambers, Randall K. Johnson, Nassirah Khandoudi, George P. Livi, Phillipe Robert, Jeffrey M. Stadel, Pamela Joy Jensen, Shelagh Wilson
  • Human G protein coupled lysophosphatidic acid receptor
    Patent number: 6344342
    Abstract: HOFNH30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HOFNH30 polypeptides and polynucleotides in terapy, and diagnostic assays for such.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: February 5, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Ping Tsui, Catherine E. Ellis, Ganesh M. Sathe, Stephanie Van Horn, Robert S. Ames, James J. Foley, Laura R. Fitzgerald, Henry M. Sarau, Jonathan K. Chambers
  • Human G protein coupled lysophosphatidic acid receptor
    Patent number: 6242572
    Abstract: HOFNH30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HOFNH30 polypeptides and polynucleotides in terapy, and diagnostic assays for such.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: June 5, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Ping Tsui, Catherine E. Ellis, Ganesh M. Sathe, Stephanie Van Horn, Robert S. Ames, James J. Foley, Laura R. Fitzgerald, Henry M. Sarau, Jonathan K. Chambers
  • Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof
    Patent number: 6238873
    Abstract: Disclosed are methods for discovering agonists and antagonists of the interaction between UDP-glucose, UDP-galactose, UDP-glucuronic acid, UDP-N-acetyl glucosamine, as well as related UDP sugars, and their cellular receptor, human KIAA0001, which may have utility in the treatment of several human diseases and disorders, including, but not limited to: infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; diabetes, obesity; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; restenosis; atherosclerosis; diseases characterized by excessive smooth muscle cell proliferation; aneurysms; wound healing; diseases characterized by loss of smooth muscle cells or reduced smooth muscle cell proliferation; stroke; ischemia; ulcers; asthma; allergies; benign prostatic hypertrophy; migraine; vomiting; psychotic and neurologic
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: May 29, 2001
    Assignee: Smithkline Beecham Corporation
    Inventors: Robert S. Ames, Anne Romanic Arnold, Jonathan K. Chambers, James Joseph Foley, Henry M. Sarau, Brian R. Stewart
  • GPR14 polypeptides
    Patent number: 6133420
    Abstract: Human GPR14 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human GPR14 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: October 17, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Robert S. Ames, Jr., Henry M. Sarau, James J. Foley, Usman Shabon, Derk Bergsma, Jonathan K. Chambers