Abstract: The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: Methods and systems consistent with the present invention allow a user to create a storage hierarchy definition in association with a workflow that models a process, to generate a plan from the workflow that reflects an instance of the process, and to generate a container in accordance with the storage hierarchy definition when the plan is generated from the workflow. The container may then be used to store an artifact that is used or produced by the plan in accordance with methods and systems of the present invention.

Abstract: Methods and system consistent with the present invention provide a workflow modeling and project planning integration tool that allows a user to model a business process or workflow, to create and activate a project plan based on the workflow, and to track the progress of the activated project plan. The tool also allows the workflow to be reused to create more than one project plan based on the workflow. Moreover, the tool simultaneously manages the execution of the plans. The integration tool may include a Web-based “Distributed Authoring and Versioning” (WebDAV) server that operates as a virtual file system for computers on a network to allow more than one user on different computer systems to view the same workflow or project plan, monitor the progress of an activated project plan, or simultaneously create and activate different plans from the same workflow.

Abstract: Methods and systems consistent with the present invention provide an integrated process modeling and project planning tool that allows an enterprise affiliate to improve a workflow that models a process. To improve the workflow, the tool initiates execution of a plan created from the workflow such that an instance of the process is at least partially performed, receives a characteristic about the performance of the plan, and modifies the workflow to reflect the characteristic so that a subsequent plan created from the modified workflow has the received characteristic.

Abstract: Methods and systems consistent with the present invention allow a user to generate a plan from the workflow that reflects an instance of a process and create a link from the plan to the workflow. Moreover, methods and systems consistent with the present invention allow a user to create a link from a task of the plan to an activity of the workflow.

Abstract: Methods and systems consistent with the present invention allow a user to create a storage hierarchy definition in association with a workflow that models a process, to generate a plan from the workflow that reflects an instance of the process, and to generate a container in accordance with the storage hierarchy definition when the plan is generated from the workflow. The container may then be used to store an artifact that is used or produced by the plan in accordance with methods and systems of the present invention.

Abstract: Methods and systems consistent with the present invention provide an integrated process modeling and project planning tool that allows an enterprise affiliate to improve resource allocation to a given plan created from a workflow that models a process. To improve resource allocation, the tool generates a plan to perform an instance of the process. The generated plan has tasks performed by resources. Each resource has capabilities that are considered when generating the plan to ensure that, for each task, a suitable one of the resources is selected to perform each task. After generating the plan, the tool receives modification information indicating that the capabilities of one of the resources has changed, and assigns the resources to the tasks to generate a new plan by using the received modification information.

Abstract: Methods and system consistent with the present invention provide a workflow modeling and project planning integration tool that allows a user to model a business process or workflow, to create and activate a project plan based on the workflow, and to track the progress of the activated project plan. The tool also allows the workflow to be reused to create more than one project plan based on the workflow. Moreover, the tool simultaneously manages the execution of the plans. The integration tool may include a Web-based “Distributed Authoring and Versioning” (WebDAV) server that operates as a virtual file system for computers on a network to allow more than one user on different computer systems to view the same workflow or project plan, monitor the progress of an activated project plan, or simultaneously create and activate different plans from the same workflow.

Abstract: Methods and systems consistent with the present invention provide an integrated process modeling and project planning tool that allows an enterprise affiliate to improve a workflow that models a process. To improve the workflow, the tool initiates execution of a plan created from the workflow such that an instance of the process is at least partially performed, receives a characteristic about the performance of the plan, and modifies the workflow to reflect the characteristic so that a subsequent plan created from the modified workflow has the received characteristic.