Abstract: The present disclosure provides means such as uses, nanoparticles, solutions, methods, kits and systems for screening target proteins for self-association properties (viscosity and opalescence) in ultra-dilute solutions. They provide means for screening a large number of target proteins at orders of magnitude lower concentrations than end-use formulations.

Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.

Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.

Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.

Abstract: One embodiment includes a method for monitoring a CIP process previously performed. The method includes accessing CIP process data stored in a CIP library. The CIP process data includes CIP phase data associated with a plurality of CIP phases in the CIP process previously performed, equipment data associated with objects used in the CIP process during one or more of the CIP phases, and consumable data associated with consumables consumed by corresponding equipment in the CIP process. In addition, the method includes displaying at least a portion of the CIP process data, and providing a graphical user interface. The graphical user interface is configured to: organize the CIP process data into at least one of (i) a plurality of CIP phases or (ii) consumable data, and sort equipment data according to one or more of the plurality of corresponding CIP phases or corresponding consumables.

Abstract: One embodiment includes a method for monitoring a CIP process previously performed. The method includes accessing CIP process data stored in a CIP library. The CIP process data includes CIP phase data associated with a plurality of CIP phases in the CIP process previously performed, equipment data associated with objects used in the CIP process during one or more of the CIP phases, and consumable data associated with consumables consumed by corresponding equipment in the CIP process. In addition, the method includes displaying at least a portion of the CIP process data, and providing a graphical user interface. The graphical user interface is configured to: organize the CIP process data into at least one of (i) a plurality of CIP phases or (ii) consumable data, and sort equipment data according to one or more of the plurality of corresponding CIP phases or corresponding consumables.

Abstract: One embodiment includes a method for simulating an operational effect of one or more changes in a CIP process. The method includes providing a graphical user interface configured to receive inputs from a user, receiving at least one proposed adjustment to one CIP phase of the CIP process, and generating a simulated CIP process based on a first set of CIP data and the at least one proposed adjustment to generate simulated CIP data based on the simulated CIP process. The simulated CIP data is displayed on the display. The simulated CIP data includes at least one of the amount or the total cost of each consumable used to generate the simulated CIP data. A total cost of the simulated CIP process is calculated, where the total cost of the simulated CIP process incorporates the proposed adjustment.

Abstract: One embodiment includes a method for simulating an operational effect of one or more changes in a CIP process. The method includes providing a graphical user interface configured to receive inputs from a user, receiving at least one proposed adjustment to one CIP phase of the CIP process, and generating a simulated CIP process based on a first set of CIP data and the at least one proposed adjustment to generate simulated CIP data based on the simulated CIP process. The simulated CIP data is displayed on the display. The simulated CIP data includes at least one of the amount or the total cost of each consumable used to generate the simulated CIP data. A total cost of the simulated CIP process is calculated, where the total cost of the simulated CIP process incorporates the proposed adjustment.

Abstract: One embodiment includes a method for monitoring a CIP process previously performed. The method includes accessing CIP process data stored in a CIP library. The CIP process data includes CIP phase data associated with a plurality of CIP phases in the CIP process previously performed, equipment data associated with objects used in the CIP process during one or more of the CIP phases, and consumable data associated with consumables consumed by corresponding equipment in the CIP process. In addition, the method includes displaying at least a portion of the CIP process data, and providing a graphical user interface. The graphical user interface is configured to: organize the CIP process data into at least one of (i) a plurality of CIP phases or (ii) consumable data, and sort equipment data according to one or more of the plurality of corresponding CIP phases or corresponding consumables.