Abstract: Disclosed herein are compositions and methods relevant to novel Opioid Receptor Scores to determine opioid responsiveness of a human individual. The Opioid Receptor Score allows determination of innate opioid responsiveness relevant to drug treatment and can be predicted and diagnosed from blood, buccal swab or saliva. In the disclosed method, an individual is genotyped for a plurality of polymorphisms in Opioid Receptor genes ?, ?, and ? (OPRM1, OPRD1, OPRK1), encoding for Opioid Receptors mu 1, delta 1, and kappa 1. The genotypes are used to compose the Opioid Receptor Scores, which relate to the opioid responsiveness of the individual.

Abstract: The present tool creates a direct extension to patients outside and within the office setting. As used with a mobile device, the tool provides guidance on prescription of drugs or supplements as affected by a known genotype. The disclosed tool will collect, tabulate and report back to the medical practice or practitioner critical live-time information that will help in their medical decision-making. The collective data on patients may be segmented to evaluate various similar attributes among patients. The results of this collection of data may be graphically displayed to illustrate variants. Some examples may be the evaluation of diagnoses, guidance on prescription of drugs or supplements as affected by a known genotype, and the effects and side effects of a treatment on functionality, mental status and its associated complications and adverse reactions.

Abstract: This invention teaches methods, devices, and systems for spasm control and pain relief in any area of the back. It comprises a plurality of adjustable programmable integrated vibratory, thermal and electrical stimulation contacts, which are strategically and symmetrically co-located in plurality of foam layers and an inflatable pillow to provide balanced relief on either side of the spine in any position from lying down to sitting up.

Abstract: A myotherapy message device for the treatment of lower back myofosical pains having two laterally spaced massage heads each having a vibrator, and optionally a heater, disposed in the massage head, an apparatus for positioning the message heads vertically and laterally permitting a user to lay upon the device for relief of myofascial pains. A method for relieving myofascial pains involves contacting the affected muscles with the two laterally spaced massage heads and applying pressure, vibration and optionally heat to the areas of contact thereby relieving tension in the muscles.