Patents by Inventor Jonathan L. Gross

Jonathan L. Gross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
    Patent number: 7008944
    Abstract: Compounds of the formula: are useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: March 7, 2006
    Assignee: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]-quinoline as 5-HT1A antagonists
    Patent number: 6821981
    Abstract: Compounds of the formula useful for the treatment of disorders, such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: November 23, 2004
    Assignee: Wyeth
    Inventors: Gary P. Stack, Megan Tran, Jonathan L. Gross, George E. M. Husbands
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
    Publication number: 20040077652
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: July 14, 2003
    Publication date: April 22, 2004
    Applicant: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Process for synthesis of 2-yl chroman derivatives
    Patent number: 6716998
    Abstract: This invention provides a process for the stereospecific preparation of 2-yl-chroman and -chromene derivatives of the formula: These compounds are useful for the preparation of optically active 2-aminomethyl- and 2-azaheterocyclylmethyl-chromans.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: April 6, 2004
    Assignee: Wyeth
    Inventor: Jonathan L. Gross
  • Process for stereoselective synthesis of 2-hydroxymethyl chromans
    Patent number: 6700001
    Abstract: A process for the stereoselective synthesis of 2-hydroxymethyl-chromans of formula (II) is provided where R, R1, R2 and R3 are as defined herein. The compound of formula (II) is prepared using an optically active benzene compound of formula (I) where R0 is as defined herein. The 2-hydroxymethyl-chroman compounds of formula (II) are useful as intermediates for preparing a variety of medicinal agents.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: March 2, 2004
    Assignee: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoxaline
    Patent number: 6617327
    Abstract: Compounds of the formula: are useful for the treatment of depression and other diseases such as obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse and related illnesses.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: September 9, 2003
    Assignee: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Process for stereoselective synthesis of 2-hydroxymethyl chromans
    Publication number: 20030105342
    Abstract: A process for the stereoselective synthesis of 2-hydroxymethyl-chromans of formula (II) is provided 1
    Type: Application
    Filed: October 4, 2002
    Publication date: June 5, 2003
    Applicant: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack
  • Process for synthesis of 2-yl chroman derivatives
    Publication number: 20030100774
    Abstract: This invention provides a process for the stereospecific preparation of 2-yl-chroman and -chromene derivatives of the formula: 1
    Type: Application
    Filed: October 4, 2002
    Publication date: May 29, 2003
    Applicant: Wyeth
    Inventor: Jonathan L. Gross
  • Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]-quinoline as 5-HT1A antagonists
    Publication number: 20020193366
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: April 25, 2002
    Publication date: December 19, 2002
    Applicant: Wyeth
    Inventors: Gary P. Stack, Megan Tran, Jonathan L. Gross, George E. M. Husbands
  • Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoxaline
    Publication number: 20020183329
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: April 23, 2002
    Publication date: December 5, 2002
    Applicant: Wyeth
    Inventors: Jonathan L. Gross, Gary P. Stack