Patents by Inventor Jonathan Lai

Jonathan Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12202888
    Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.
    Type: Grant
    Filed: April 28, 2023
    Date of Patent: January 21, 2025
    Assignee: Albert Einstein College of Medicine
    Inventors: Jacqueline M. Achkar, Jonathan Lai, Elise Ishida, Daniel Hofmann, Tingting Chen
  • Publication number: 20230365663
    Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 16, 2023
    Applicant: Albert Einstein College of Medicine
    Inventors: Jacqueline M. Achkar, Jonathan Lai, Elise Ishida, Daniel Hofmann, Tingting Chen
  • Publication number: 20230167447
    Abstract: Compositions, systems, and methods are described herein to modulate (reduce/inhibit) expression/activity of FNIP1 and/or FNIP2 (“FNIP1/FNIP2”) in a cell, animal or human subject, which can prevent, ameliorate, or treat diseases (neuromuscular or neurodegenerative diseases). Methods are described for modulating (reducing/inhibiting) FNIP1/FNIP2 expression/activity via a modulator to regulate FNIP1/FNIP2 expression/activity. Also included are compositions containing modulators that regulate FNIP1/FNIP2 expression/activity. Pharmaceutical compositions, kits, and methods of delivering compositions used in modulating, reducing, or inhibiting FNIP1/FNIP2 expression/activity are described. Methods to develop, synthesize, or produce modulators, and treat ALS and related disorders (TDP-43 proteinopathies, oxidative stress, obesity, anemia, or ischemic diseases) are provided.
    Type: Application
    Filed: November 30, 2022
    Publication date: June 1, 2023
    Inventors: Yao Zong Ng, Bertrand Adanve, Jonathan Lai
  • Patent number: 11643455
    Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: May 9, 2023
    Assignee: Albert Einstein College of Medicine
    Inventors: Jacqueline M. Achkar, Jonathan Lai, Elise Ishida, Daniel Hofmann, Tingting Chen
  • Publication number: 20220277387
    Abstract: Disclosed herein are system, method, and computer program product embodiments for generating optimized data structure objects. In a given embodiment, a server receives a request to identify a set of data structure objects from a plurality of data structure objects for a specified vehicle and a specified user and based on user objective data and an attribute. The server may generate the plurality of data structure objects within constraints of the user objective data, policy data, and the attribute. The server may identify the set of data structure objects from the plurality of data structure objects. Each data structure object of the set is within a threshold distance to a value of at least one dimension of a set of the dimensions of the set of dimensions of a model.
    Type: Application
    Filed: February 26, 2021
    Publication date: September 1, 2022
    Applicant: Capital One Services, LLC
    Inventors: Drake R. SANDERSON, Rukmani THIRUPPATHI, Adam GERNES, Krishna Mohan BIBIREDDY, Taylor Elliott GERON, Thomas BUSATH, Jonathan LAI, Abhishek TEWARI
  • Publication number: 20210163578
    Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.
    Type: Application
    Filed: April 12, 2019
    Publication date: June 3, 2021
    Inventors: Jacqueline M. Achkar, Jonathan Lai, Elise Ishida, Daniel Hofmann, Tingting Chen
  • Publication number: 20210130443
    Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.
    Type: Application
    Filed: December 15, 2020
    Publication date: May 6, 2021
    Inventors: Jacqueline M. Achkar, Jonathan Lai, Elise Ishida, Daniel Hofmann, Tingting Chen
  • Patent number: 10590060
    Abstract: A process for synthesizing at least one levulinate ester, said process comprising the reaction of furfuryl alcohol with at least one other alcohol in the presence of water and at least one catalyst, said furfuryl alcohol being present in a quantity of at least 5% by weight, based on the total weight of the alcohols, and said catalyst comprising at least one triflate ligand and at least one metal selected from bismuth, gallium, aluminum, tin and iron.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: March 17, 2020
    Assignees: LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERS
    Inventors: Alban Chappaz, Francois Jerome, Karine De Oliveira Vigier, Eric Muller, Jonathan Lai, Matthieu Corbet, Didier Morvan
  • Publication number: 20190375703
    Abstract: A process for synthesizing at least one levulinate ester, said process comprising the reaction of furfuryl alcohol with at least one other alcohol in the presence of water and at least one catalyst, said furfuryl alcohol being present in a quantity of at least 5% by weight, based on the total weight of the alcohols, and said catalyst comprising at least one triflate ligand and at least one metal selected from bismuth, gallium, aluminum, tin and iron.
    Type: Application
    Filed: June 30, 2017
    Publication date: December 12, 2019
    Inventors: Alban CHAPPAZ, Francois JEROME, Karine DE OLIVEIRA VIGIER, Eric MULLER, Jonathan LAI, Matthieu CORBET, Didier MORVAN
  • Patent number: 8793175
    Abstract: A Single Tranche Synthetic ABS product designed to replicate economics returns of structured finance collateralized debt obligations (SF CDO) securities, allow parties to express a leveraged and/or correlation view on a custom ABS portfolio by transferring a credit risk of a particular transacted tranche of a portfolio in swap format, and account for an available funds cap risk of the ABS securities within the underlying portfolio in a manner equivalent to a cash analog based on the same underlying portfolio with sequential pay structure.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: July 29, 2014
    Assignee: Barclays Capital Inc.
    Inventors: Jonathan Lai, Jeong Gu Lee
  • Publication number: 20100325066
    Abstract: A Single Tranche Synthetic ABS product is designed to replicate economics returns of structured finance collateralized debt obligations (SF CDO) securities and allow parties to express a leveraged and/or correlation view on a custom ABS portfolio by transferring a credit risk of a particular transacted tranche of a portfolio in swap format. The inventions described herein account for an available funds cap risk of the ABS securities within the underlying portfolio in a manner equivalent to a cash analog based on the same underlying portfolio with sequential pay structure.
    Type: Application
    Filed: July 7, 2010
    Publication date: December 23, 2010
    Applicant: BARCLAYS CAPITAL INC.
    Inventors: Jonathan LAI, Jeong Gu LEE
  • Publication number: 20100280970
    Abstract: A Single Tranche Synthetic ABS product is designed to replicate economics returns of structured finance collateralized debt obligations (SF CDO) securities and allow parties to express a leveraged and/or correlation view on a custom ABS portfolio by transferring a credit risk of a particular transacted tranche of a portfolio in swap format. The inventions described herein account for an available funds cap risk of the ABS securities within the underlying portfolio in a manner equivalent to a cash analog based on the same underlying portfolio with sequential pay structure.
    Type: Application
    Filed: July 7, 2010
    Publication date: November 4, 2010
    Applicant: BARCLAYS CAPITAL INC.
    Inventors: Jonathan LAI, Jeong Gu LEE
  • Publication number: 20080154789
    Abstract: A Single Tranche Synthetic ABS product is designed to replicate economics returns of structured finance collateralized debt obligations (SF CDO) securities and allow parties to express a leveraged and/or correlation view on a custom ABS portfolio by transferring a credit risk of a particular transacted tranche of a portfolio in swap format. The inventions described herein account for an available funds cap risk of the ABS securities within the underlying portfolio in a manner equivalent to a cash analog based on the same underlying portfolio with sequential pay structure.
    Type: Application
    Filed: September 6, 2007
    Publication date: June 26, 2008
    Applicant: Lehman Brothers Inc.
    Inventors: Jonathan Lai, Jeong Gu Lee