Patents by Inventor Jonathan Lei
Jonathan Lei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250065563Abstract: Self-limiting electrospray compositions including a non-charge-dissipative component and/or a charge-dissipative component. Self-limiting electrospray composition including a plurality of charge-dissipative components and excluding a non-charge-dissipative component. Methods for forming layers of self-limiting thickness. Methods for determining a conductivity of a material. Methods for repairing a flaw in a layer on a surface of an object.Type: ApplicationFiled: November 11, 2024Publication date: February 27, 2025Inventors: Jonathan P. SINGER, Lin LEI
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Publication number: 20250051433Abstract: Provided herein are anti-TSLP antibodies or antigen-binding fragments thereof, isolated poly nucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.Type: ApplicationFiled: December 23, 2022Publication date: February 13, 2025Inventors: Run LEI, Chongtian GUO, Pengcheng FAN, Zhihao XU, Qiang SUN, Jonathan Jian WANG
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Publication number: 20250024653Abstract: An approach for heat management in wearable devices is provided. One or more vibration enhanced convection heat transfer surfaces may be incorporated to exterior surfaces of a wearable device. A controller may take into account ambient temperature, available power expected power consumption by the vibration enhanced convection heat transfer surface(s), and/or expected heat reduction, and activate the vibration enhanced convection heat transfer surface(s) to expel heat from the wearable device. Operational parameters of the vibration enhanced convection heat transfer surface(s) such as a frequency and/or an amplitude of vibration may also be determined and set based on the internal and external factors including a shape, a location, and/or a size of the vibration enhanced convection heat transfer surface(s).Type: ApplicationFiled: July 13, 2023Publication date: January 16, 2025Applicant: Meta Platforms Technologies, LLCInventors: Dusan COSO, Nagi ELABBASI, Hongtao GUO, Shenghui LEI, Sadegh AGHAEI, Jonathan Robert PETERSON
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Publication number: 20240424094Abstract: Nucleic acid mutation associated with specific cancers can be targeted using a CRISPR detector with a special mRNA pay load containing instructions for the target cell to express a universal cancer antigen.Type: ApplicationFiled: October 4, 2022Publication date: December 26, 2024Applicant: CancerVAX Inc.Inventors: Ryan Davies, Jonathan Lei
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Publication number: 20230265069Abstract: Disclosed are compounds, compositions, and methods for treating an infection by an enveloped virus in a patient in need thereof. The disclosed compounds may be derived from prazole compounds and may inhibit or block the release of an enveloped virus from an infected cell. As such, the disclosed methods may include methods of treating a viral infection by administering the disclosed compounds or pharmaceutical compositions comprising the disclosed compounds.Type: ApplicationFiled: April 23, 2021Publication date: August 24, 2023Inventors: Jonathan Leis, Chi-Hao Luan, James Edmund Audia
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Patent number: 11666562Abstract: Disclosed are methods and compositions for treating an infection by an enveloped virus in a patient in need thereof. The methods include administering to the patient a compound that inhibits or blocks release of the enveloped virus from an infected cell. As such, the disclosed methods include methods of inhibiting or blocking release of an enveloped virus from a cell. The disclosed methods may include administering to the patient a prazole-type compound having a substituted (pyridin-2-yl)methylsulfinyl-benzimidazole core.Type: GrantFiled: April 2, 2021Date of Patent: June 6, 2023Assignee: Northwestern UniversityInventors: Jonathan Leis, Chi-Hao Luan
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Patent number: 11369622Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: GrantFiled: August 5, 2020Date of Patent: June 28, 2022Assignees: Northwestern University, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: Jonathan Leis, Carol Carter
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Publication number: 20210308114Abstract: Disclosed are methods and compositions for treating an infection by an enveloped virus in a patient in need thereof. The methods include administering to the patient a compound that inhibits or blocks release of the enveloped virus from an infected cell. As such, the disclosed methods include methods of inhibiting or blocking release of an enveloped virus from a cell. The disclosed methods may include administering to the patient a prazole-type compound having a substituted (pyridin-2-yl)methylsulfinyl-benzimidazole core.Type: ApplicationFiled: April 2, 2021Publication date: October 7, 2021Inventors: Jonathan LEIS, Chi-Hao LUAN
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Publication number: 20200368258Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: ApplicationFiled: August 5, 2020Publication date: November 26, 2020Applicants: Northwestern University, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: Jonathan Leis, Carol Carter
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Patent number: 10765687Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: GrantFiled: March 22, 2019Date of Patent: September 8, 2020Assignees: Northwestern University, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: Jonathan Leis, Carol Carter
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Publication number: 20190209589Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: ApplicationFiled: March 22, 2019Publication date: July 11, 2019Applicants: Northwestern University, THE RESEARCH FOUNDATION FOR THE STATE OF UNIVERSITY OF NEW YORKInventors: Jonathan Leis, Carol Carter
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Patent number: 10300080Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: GrantFiled: November 10, 2015Date of Patent: May 28, 2019Assignees: Northwestern University, The Research Foundation for the State UniversityInventors: Jonathan Leis, Carol Carter
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Publication number: 20170095485Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: ApplicationFiled: November 10, 2015Publication date: April 6, 2017Inventors: Jonathan Leis, Carol Carter
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Publication number: 20140179637Abstract: A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.Type: ApplicationFiled: December 21, 2013Publication date: June 26, 2014Applicants: The Research Foundation for The State University of New York, Northwestern UniversityInventors: Jonathan Leis, Carol Carter
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Publication number: 20070005456Abstract: A self-contained business transaction capsule to conduct a wireless transaction includes data regarding the wireless transaction. Transaction logic is provided to complete the wireless transaction. The self-contained business transaction capsule is adapted to be broadcasted to and stored on a portable electronic device.Type: ApplicationFiled: September 8, 2006Publication date: January 4, 2007Applicant: WARP 9 INC.Inventor: Jonathan Lei
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Publication number: 20060165030Abstract: A method of executing programmable instructions includes receiving at a device a mobile agent from a mobile agent dispatching device. The mobile agent includes a state of a virtual machine. The method also includes executing at the device one or more instructions identified by the mobile agent, thereby changing the state of the virtual machine.Type: ApplicationFiled: December 7, 2004Publication date: July 27, 2006Inventors: Brian Fox, Jonathan Lei
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Publication number: 20060123396Abstract: A method for executing operations on a device includes executing one or more bytecode language instructions associated with a mobile agent. The mobile agent includes a state of a virtual machine and the bytecode language includes instructions such WARP, MESG; ESEL, ALERT, BROWSE, CAPS, SLEEP, and GPS.Type: ApplicationFiled: December 7, 2004Publication date: June 8, 2006Inventors: Brian Fox, Jonathan Lei
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Publication number: 20050243885Abstract: The invention is achieved by using single or multiple laser sources (laser diodes) in a configuration such that when it is coupled with a dichroic substrate the laser sources outputs are coupled to produce a single desired output. The dismounted soldiers in the Department of Defense are overloaded with equipment they must carry into the combat environment. Due to many advancements in laser technology, laser devices have been produced to enhance the soldiers' war fighting capability or to provide them with realistic training aids. Unfortunately, these devices have separate housings, controls, power supplies, controls, laser sources and optics which leads to an undesired weight, space and power claims. The present invention consolidates multiple laser functions for the dismounted soldier into a single package with shared power supplies, optics and laser sources thus, minimizing the claim on weight, space, and power.Type: ApplicationFiled: April 29, 2004Publication date: November 3, 2005Inventors: John Nettleton, Dallas Barr, Jonathan Lei
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Publication number: 20050146705Abstract: An improvement in a single-shot laser rangefinder having a photo-detector for detecting return laser pulse signals, a signal amplifier for amplifying the return laser pulse signals, and a range processor for determining the range of a reflecting object from the round trip time of flight of the return laser pulse signals. The difference in time at which the strongest laser pulse signal crosses the threshold for detection and the weakest laser pulse signal crosses the threshold for detection causes a timing error in the measured range.Type: ApplicationFiled: December 24, 2003Publication date: July 7, 2005Inventors: Jonathan Lei, Bradley Schilling, Dallas Barr