Abstract: The present invention relates anti-microbial antibody signatures of inflammatory bowel disease and their use in early and accurate diagnosis of disease including ulcerative colitis (UC) and Crohn's disease (CD).

Abstract: Identification of autoantibodies associated with Crohn's disease useful in diagnosis and management using an innovative protein array technology, namely nucleic acid programmable protein arrays (NAPPA) and applications relating thereto. Overall, reactivity of IgG autoantibodies was stronger than that of IgA autoantibodies; however, IgA autoantibodies showed greater differential reactivity between cases and controls. Four IgA autoantibodies against SNRPB, PRPH, PTTG1 and SNAI1 were newly identified with sensitivities above 15% at 95% specificity, among which anti-SNRPB-IgA had the highest sensitivity of 24.0%. Autoantibodies associated with specific disease subtypes were also found.

Abstract: Identification of autoantibodies associated with Crohn's disease useful in diagnosis and management using an innovative protein array technology, namely nucleic acid programmable protein arrays (NAPPA) and applications relating thereto. Overall, reactivity of IgG autoantibodies was stronger than that of IgA autoantibodies; however, IgA autoantibodies showed greater differential reactivity between cases and controls. Four IgA autoantibodies against SNRPB, PRPH, PTTG1 and SNAI1 were newly identified with sensitivities above 15% at 95% specificity, among which anti-SNRPB-IgA had the highest sensitivity of 24.0%. Autoantibodies associated with specific disease subtypes were also found.

Abstract: A system and method permits a primary online service to award and redeem incentive points to users of a social networking or other third-party site that operates independently of the primary online service. The primary online service publishes copies of a widget on the social networking site. The widget communicates with the social networking site through an API published by the operators of the social networking site. When user of the social networking site activates the widget, the primary website awards incentive points to the user based on the user's activities at the social networking site. These activities are tracked by the widget, which also displays to the user the balance of award points and advertising messages. The user can redeem points for goods, services or other consideration and can buy and sell points with other users.

Abstract: The present invention relates to the field of computer software. More specifically, the present invention relates to methods of assisting aggregation of form-enabled web services. Systems and methods for handling the submission of user data into a plurality of form-enabled web sites are disclosed. The improved system allows for the presentation of a unified user interface, pre-filling of forms in order to increase user efficiency, and a fully automatic interface to the aggregated form-enabled web services.