Abstract: The present invention relates to particular ROR gamma inhibitors for use for treating ROR? dependent cancer or metastasis, particularly prostate cancer, such as castration-resistant prostate cancer.

Abstract: A surgical guide includes a base and a drill guide coupled to the base. The drill guide includes a drill guide body defining a drill bore for receiving a drill bit and extending through the drill guide, the drill guide being configured to translate relative the base to adjust a drill guide angle defined by the drill bore and the base, the drill guide further being configured to transition between a locked state and an unlocked state, wherein the drill guide angle is fixed in the locked state and the drill guide angle is adjustable in the unlocked state.

Abstract: Convertible shoulder arthroplasty systems and configurations for components thereof are described. In some embodiments, an implant component is provided. The implant component includes one of a glenoid component comprising a concave outer surface, and a glenosphere component comprising a convex outer surface. The system may also include one of a first baseplate comprising a central bossed portion extending from an underside thereof and a central aperture disposed therethrough or a second baseplate comprising a central bossed portion extending from a top side thereof and a central aperture disposed there through. In some implementations, an anchor boss comprising a central aperture extending therethrough is provided. The system may include a central compression screw configured to be secured through the central aperture and, thereby, securely compress the first baseplate, the second baseplate or the anchor boss against the patient bone.

Abstract: The invention relates to a modular system (1) for moving storage elements, including a plurality of adjacent modules (200) and at least one bin (300) that can be moved in the modular structure from one module to an adjacent module, with a module including a frame (210) of rectangular parallelepiped shape including bars (212, 213, 214, 215) that are assembled together, at least either the modules or the bins including at least one actuator (400) and the other, modules or bins, comprising including complementary cavities (700), either the actuators or the cavities being fixed to the bars of the frame, the other being fixed to the bin, the actuators and the cavities being configured to cooperate so as to move a bin located at least partially inside one module in translation to an adjacent module.

Abstract: A pre-operative surgical planning system utilizes machine learning classification to provide candidate elements of a pre-operative surgical plan. The pre-operative surgical planning system may comprise a machine learning reconstruction engine that is trained with artificial computer models of physiologically compromised anatomical structures.

Abstract: There is provided an adornment having a machine readable code integrated therein for establishing a communication channel over a network between a computing device and a server, the adornment comprising an adornment body sized and shaped for wearing on an appendage of a body of a human, wherein the machine readable code comprises a plurality of gems which are inlaid in the adornment body, wherein the machine readable code encodes an identifier for establishing the communication channel between a computing device imaging said plurality of gems and a remote data storage device storing at least one media content item designated for presentation on a display of the computing device.

Abstract: A method and apparatus for proper sizing and centralization of a shoulder humerus implant are provided. The method and apparatus replicate the proper stem height and position for a shoulder humerus implant, and may be used during trialing and maintaining the proper height and orientation during implantation. The apparatus further assists in maintaining the shoulder humerus implant stem at the center of the humeral canal to allow for proper cementing technique, and facilitates selection of the appropriate humeral head replacement.

Abstract: A garment includes a garment body formed of at least one fabric. At least one padded portion is coupled to the garment body so as to extend inwardly of the garment body and at least partially occupy a volume defined by a space between a portion of the garment body and a correspondingly positioned portion of a wearer's body. A method includes disposing padding configured to be accommodated in a region of a body of the wearer which is spaced apart from a portion of a garment body of the exercise garment when worn so as to be inwardly projecting of the garment body in a position generally corresponding to the region of the body of the wearer, to thereby insulate and/or wick moisture away from the skin.

Abstract: There is provided an adornment having a machine readable code integrated therein for establishing a communication channel over a network between a computing device and a server, the adornment comprising an adornment body sized and shaped for wearing on an appendage of a body of a human, wherein the machine readable code comprises a plurality of gems which are inlaid in the adornment body, wherein the machine readable code encodes an identifier for establishing the communication channel between a computing device imaging said plurality of gems and a remote data storage device storing at least one media content item designated for presentation on a display of the computing device.

Abstract: A method and apparatus for proper sizing and centralization of a shoulder humerus implant are provided. The method and apparatus replicate the proper stem height and position for a shoulder humerus implant, and may be used during trialing and maintaining the proper height and orientation during implantation. The apparatus further assists in maintaining the shoulder humerus implant stem at the center of the humeral canal to allow for proper cementing technique, and facilitates selection of the appropriate humeral head replacement.

Abstract: A method for managing a metrology system includes receiving a part, identifying, with a processing device, a part type associated with the part, retrieving, with the processing device, test rule logic associated with the part type from a database, retrieving, with the processing device, measurement data associated with the identified part type, processing, with the processing device, the measurement data, applying, with the processing device, the test rule logic to the processed measurement data to determine whether the part should be measured, outputting the part responsive to determining that the part should not be measured, and incrementing, with the processing device, a counter and saving a value of the counter in the database responsive to outputting the part responsive to determining that the part should not be measured.

Abstract: Embodiments herein relate generally to distribution of flow into vessels containing packed beds of media. An example application of such beds is to pressure swing or temperature swing adsorption systems. Systems herein may include a vessel and a distributor for distributing flow into a lower portion of the vessel. The system may include: a vessel comprising a top head and a bottom head; and a bottom head feed/effluent nozzle. A lower distributor having at least one flow permitting surface is disposed within the vessel and encompasses an inlet of the bottom head feed/effluent nozzle. A flow gap is formed between a bottom portion of the lower distributor and the bottom head feed/effluent nozzle.

Abstract: Embodiments herein relate generally to distribution of flow into vessels containing packed beds of media. An example application of such beds is to pressure swing or temperature swing adsorption systems. Systems herein may include a vessel and a distributor for distributing flow into a lower portion of the vessel. The system may include: a vessel comprising a top head and a bottom head; and a bottom head feed/effluent nozzle. A lower distributor having at least one flow permitting surface is disposed within the vessel and encompasses an inlet of the bottom head feed/effluent nozzle. A flow gap is formed between a bottom portion of the lower distributor and the bottom head feed/effluent nozzle.

Abstract: A method identifies time sensitive processing sequences within a production environment using a computerized device. The processing sequences perform operations utilizing one or more tools. The method also identifies non-committed work in process items that are grouped in non-committed lots for release into one or more of the time sensitive processing sequences, and identifies committed work in process items that are being processed in committed lots within the time sensitive processing sequences, using the computerized device. The method sorts the non-committed lots by a predetermined priority, again using the computerized device. Starting with the highest priority non-committed lot (and continuing with others of the non-committed lots in priority order) the method determines whether there is available tool capacity to process a non-committed lot through each corresponding time sensitive processing sequence using the computerized device.

Abstract: A method for managing a metrology system includes receiving a part, identifying, with a processing device, a part type associated with the part, retrieving, with the processing device, test rule logic associated with the part type from a database, retrieving, with the processing device, measurement data associated with the identified part type, processing, with the processing device, the measurement data, applying, with the processing device, the test rule logic to the processed measurement data to determine whether the part should be measured, outputting the part responsive to determining that the part should not be measured, and incrementing, with the processing device, a counter and saving a value of the counter in the database responsive to outputting the part responsive to determining that the part should not be measured.