Patents by Inventor Jonathan Lewis Telfer

Jonathan Lewis Telfer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • vectored vaccines against and methods of use
    Patent number: 8703153
    Abstract: The invention provides an attenuated Salmonella vaccine vector comprising one or more heterologous polynucleotides that encode immunogenic Chlamydial peptides. In one embodiment, the attenuated Salmonella vaccine vector comprises aroC and ssaV attenuating mutations. The heterologous polynucleotides encoding the immunogenic Chlamydial peptides can be under the control of an inducible promoter such as a Salmonella ssaG promoter. In one embodiment of the invention, the immunogenic Chlamydial peptide is a PmpG peptide, for instance, a CT110, CT84 or CT40 peptide.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: April 22, 2014
    Inventors: Jonathan Lewis Telfer, Mark Richard Redfern, Michael Joseph Lacy
  • VACCINES AGAINST CLOSTRIDIUM DIFFICILE AND METHODS OF USE
    Publication number: 20140044749
    Abstract: Attenuated microorganisms expressing Clostridium difficile antigen(s), and methods of using the same for vaccination of patients are disclosed The invention provides an attenuated microorganism expressing an immunogenic portion of a C difficile Toxin A C-terminal repeat region and/or a C difficile Toxin B C-terminal repeat region The microorganism is an attenuated Salmonella comprising an integrated gene expression cassette that directs the expression of the immunogenic peptide from an in vivo inducible promoter.
    Type: Application
    Filed: August 12, 2013
    Publication date: February 13, 2014
    Applicant: PROKARIUM LTD.
    Inventors: Jonathan Lewis TELFER, Lisa Caproni
  • VACCINES AGAINST CLOSTRIDIUM DIFFICILE AND METHODS OF USE
    Publication number: 20120020996
    Abstract: Attenuated microorganisms expressing Clostridium difficile antigen(s), and methods of using the same for vaccination of patients are disclosed The invention provides an attenuated microorganism expressing an immunogenic portion of a C difficile Toxin A C-terminal repeat region and/or a C difficile Toxin B C-terminal repeat region The microorganism is an attenuated Salmonella comprising an integrated gene expression cassette that directs the expression of the immunogenic peptide from an in vivo inducible promoter.
    Type: Application
    Filed: August 6, 2009
    Publication date: January 26, 2012
    Inventors: Jonathan Lewis Telfer, Lisa Caproni
  • SALMONELLA VECTORED VACCINES AGAINST CHLAMYDIA AND METHODS OF USE
    Publication number: 20110268760
    Abstract: The invention provides an attenuated Salmonella vaccine vector comprising one or more heterologous polynucleotides that encode immunogenic Chlamydial peptides. In one embodiment, the attenuated Salmonella vaccine vector comprises aroC and ssaV attenuating mutations. The heterologous polynucleotides encoding the immunogenic Chlamydial peptides can be under the control of an inducible promoter such as a Salmonella ssaG promoter. In one embodiment of the invention, the immunogenic Chlamydial peptide is a PmpG peptide, for instance, a CT110, CT84 or CT40 peptide.
    Type: Application
    Filed: June 16, 2009
    Publication date: November 3, 2011
    Inventors: Jonathan Lewis Telfer, Mark Richard Redfern, Michael Joseph Lacy