Patents by Inventor Jonathan M. Cannata
Jonathan M. Cannata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240001157Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: September 11, 2023Publication date: January 4, 2024Inventors: Jonathan M. CANNATA, Ryan MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Publication number: 20240001158Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: September 11, 2023Publication date: January 4, 2024Inventors: Jonathan M. CANNATA, Ryan MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Patent number: 11813484Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: GrantFiled: November 27, 2019Date of Patent: November 14, 2023Assignee: HistoSonics, Inc.Inventors: Jonathan M. Cannata, Ryan Miller, Alexander P. Duryea, Dejan Teofilovic, Zeljko Mladenovic, Aleksandra Rakic, Joshua Stopek
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Publication number: 20230310901Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: May 2, 2023Publication date: October 5, 2023Inventors: Jonathan M. CANNATA, Ryan M. MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Publication number: 20230310900Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: May 2, 2023Publication date: October 5, 2023Inventors: Jonathan M. CANNATA, Ryan M. MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Patent number: 11648424Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: GrantFiled: July 15, 2020Date of Patent: May 16, 2023Assignee: HistoSonics Inc.Inventors: Jonathan M. Cannata, Ryan Miller, Alexander P. Duryea, Dejan Teofilovic, Zeljko Mladenovic, Aleksandra Rakic, Joshua Stopek
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Publication number: 20200346046Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: July 15, 2020Publication date: November 5, 2020Inventors: Jonathan M. CANNATA, Ryan MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Publication number: 20200164231Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: ApplicationFiled: November 27, 2019Publication date: May 28, 2020Inventors: Jonathan M. CANNATA, Ryan MILLER, Alexander P. DURYEA, Dejan TEOFILOVIC, Zeljko MLADENOVIC, Aleksandra RAKIC, Joshua STOPEK
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Publication number: 20190275353Abstract: Methods and devices for producing cavitation in tissue are provided. In one embodiment, a shock scattering method of Histotripsy therapy comprises delivering an initiation pressure waveform from an ultrasound therapy transducer into tissue, the initiation pressure waveform being configured to produce at least one bubble in the tissue, delivering a scattering pressure waveform from the ultrasound therapy transducer into the at least one bubble within a life-cycle of the at least one bubble, and producing cavitation nuclei near the at least one bubble with the scattering pressure waveform. The scattering pressure waveform can be delivered during the life-cycle of the at least one bubble. In some embodiments, the scattering pressure waveform is delivered within 5 ?s to 1 s of the initiation pressure waveform. Systems for performing shock scattering Histotripsy therapy are also discussed.Type: ApplicationFiled: May 13, 2019Publication date: September 12, 2019Inventors: Jonathan M. CANNATA, Timothy L. HALL, Adam D. MAXWELL, Dejan TEOFILOVIC
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Patent number: 10293187Abstract: Methods and devices for producing cavitation in tissue are provided. In one embodiment, a shock scattering method of Histotripsy therapy comprises delivering an initiation pressure waveform from an ultrasound therapy transducer into tissue, the initiation pressure waveform being configured to produce at least one bubble in the tissue, delivering a scattering pressure waveform from the ultrasound therapy transducer into the at least one bubble within a life-cycle of the at least one bubble, and producing cavitation nuclei near the at least one bubble with the scattering pressure waveform. The scattering pressure waveform can be delivered during the life-cycle of the at least one bubble. In some embodiments, the scattering pressure waveform is delivered within 5 ?s to 1 s of the initiation pressure waveform. Systems for performing shock scattering Histotripsy therapy are also discussed.Type: GrantFiled: July 3, 2014Date of Patent: May 21, 2019Assignees: HISTOSONICS, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Jonathan M. Cannata, Timothy L. Hall, Adam D. Maxwell, Dejan Teofilovic
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Publication number: 20150011916Abstract: Methods and devices for producing cavitation in tissue are provided. In one embodiment, a shock scattering method of Histotripsy therapy comprises delivering an initiation pressure waveform from an ultrasound therapy transducer into tissue, the initiation pressure waveform being configured to produce at least one bubble in the tissue, delivering a scattering pressure waveform from the ultrasound therapy transducer into the at least one bubble within a life-cycle of the at least one bubble, and producing cavitation nuclei near the at least one bubble with the scattering pressure waveform. The scattering pressure waveform can be delivered during the life-cycle of the at least one bubble. In some embodiments, the scattering pressure waveform is delivered within 5 ?s to 1 s of the initiation pressure waveform. Systems for performing shock scattering Histotripsy therapy are also discussed.Type: ApplicationFiled: July 3, 2014Publication date: January 8, 2015Inventors: Jonathan M. CANNATA, Timothy L. HALL, Adam D. MAXWELL, Dejan TEOFILOVIC
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Publication number: 20100171395Abstract: An ultrasonic array transducer having an array of piezoelectric elements may be made with a curvature which may enable the piezoelectric elements to control the way in which ultrasonic energy is focused by the transducer. A substrate that has a set of element electrodes on a surface of the substrate may be created. Each element electrode may be electrically isolated from the others and configured to correspond to the location of one of the piezoelectric elements. A piezoelectric component which includes piezoelectric material may be bonded to the substrate such that each element electrode is juxtaposed next to the piezoelectric component. The surface of the substrate and/or to the piezoelectric material may have the curvature while they are separated and prior to the bonding. The bonding may be performed in a manner that results in the array of piezoelectric elements having the curvature.Type: ApplicationFiled: October 23, 2009Publication date: July 8, 2010Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Jonathan M. Cannata, Jay A. Williams, K. Kirk Shung
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Patent number: 7695784Abstract: Methods and systems are described for making posts and kerfs in an interdigital bonded composite. The desired alignment criteria for a plurality of posts and kerfs in a pair of slabs are determined, as well as the desired widths W of the posts and the desired widths K of the kerfs. The posts in the first slab are configured to be received into corresponding kerfs in the second slab, and vice versa, so that the pair of slabs can be interdigitated to generate a composite. At least one of an alignment post and an alignment kerf are created, in at least one of the slabs. The alignment posts and the alignment kerf are configured to allow the plurality of posts and kerfs to be correctly positioned and aligned, in accordance with the desired alignment criteria.Type: GrantFiled: July 23, 2007Date of Patent: April 13, 2010Assignee: University of Southern CaliforniaInventors: Jay A. Williams, Jonathan M. Cannata, Ruibin Liu, K. Kirk Shung