Patents by Inventor Jonathan M. Cohen

Jonathan M. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200121673
    Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
    Type: Application
    Filed: October 25, 2019
    Publication date: April 23, 2020
    Applicant: Wyeth, LLC
    Inventors: Syed M. Shah, Christopher Richard Diorio, Eric C. Ehrnsperger, Xu Meng, Kadum A. Al Shareffi, Jonathan Marc Cohen
  • Publication number: 20200088643
    Abstract: Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An apparatus can include an assay chip that includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits emission energy; at least one element for directing the emission energy in a particular direction; and a light path along which the emission energy travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the assay chip. The instrument includes an excitation light source for exciting the sample in each sample well; a plurality of sensors corresponding the sample wells. Each sensor may detect emission energy from a sample in a respective sample well. The instrument includes at least one optical element that directs the emission energy from each sample well towards a respective sensor of the plurality of sensors.
    Type: Application
    Filed: November 19, 2019
    Publication date: March 19, 2020
    Applicant: Quantum-Si Incorporated
    Inventors: Jonathan M. Rothberg, Ali Kabiri, Jason W. Sickler, Brett J. Gyarfas, Jeremy Lackey, Gerard Schmid, Benjamin Cipriany, Jack Jewell, Lawrence C. West, Michael Ferrigno, Paul E. Glenn, Adam Ezra Cohen, Anthony Bellofiore
  • Patent number: 10533945
    Abstract: Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An apparatus can include an assay chip that includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits emission energy; at least one element for directing the emission energy in a particular direction; and a light path along which the emission energy travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the assay chip. The instrument includes an excitation light source for exciting the sample in each sample well; a plurality of sensors corresponding the sample wells. Each sensor may detect emission energy from a sample in a respective sample well. The instrument includes at least one optical element that directs the emission energy from each sample well towards a respective sensor of the plurality of sensors.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: January 14, 2020
    Assignee: Quantum-Si Incorporated
    Inventors: Jonathan M. Rothberg, Ali Kabiri, Jason W. Sickler, Brett J. Gyarfas, Jeremy Lackey, Gerard Schmid, Benjamin Cipriany, Jack Jewell, Lawrence C. West, Michael Ferrigno, Paul E. Glenn, Adam Ezra Cohen, Anthony Bellofiore
  • Patent number: 10507206
    Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: December 17, 2019
    Assignee: Wyeth, LLC
    Inventors: Syed M. Shah, Christopher Richard Diorio, Eric C. Ehrnsperger, Xu Meng, Kadum A. Al Shareffi, Jonathan Marc Cohen
  • Patent number: 10496162
    Abstract: The systems and methods described herein assist persons with the use of computers based on eye gaze, and allow such persons to control such computing systems using various eye trackers. The systems and methods described herein use eye trackers to control cursor (or some other indicator) positioning on an operating system using the gaze location reported by the eye tracker. The systems and methods described herein utilize an interaction model that allows control of a computer using eye gaze and dwell. The data from eye trackers provides a gaze location on the screen. The systems and methods described herein control a graphical user interface that is part of an operating system relative to cursor positioning and associated actions such as Left-Click, Right-Click, Double-Click, and the like. The interaction model presents appropriate user interfaces to navigate the user through applications on the computing system.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: December 3, 2019
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Harish Sripad Kulkarni, Dwayne Lamb, Ann M Paradiso, Eric N Badger, Jonathan Thomas Campbell, Peter John Ansell, Jacob Daniel Cohen
  • Publication number: 20190314365
    Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 17, 2019
    Applicant: Wyeth, LLC
    Inventors: Syed M. Shah, Christopher Richard Diorio, Eric C. Ehrnsperger, Xu Meng, Kadum A. Al Shareffi, Jonathan Marc Cohen
  • Patent number: 10376505
    Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 13, 2019
    Assignee: Wyeth, LLC
    Inventors: Syed M. Shah, Christopher Richard Diorio, Eric C. Ehrnsperger, Xu Meng, Kadum A. Al Shareffi, Jonathan Marc Cohen
  • Patent number: 10307417
    Abstract: The present invention provides compositions comprising methylnaltrexone or a salt thereof, and compositions and formulations thereof, for oral administration.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: June 4, 2019
    Assignee: Wyeth, LLC
    Inventors: Syed M. Shah, Christopher Richard Diorio, Eric C. Ehrnsperger, Xu Meng, Kadum A. Al Shareffi, Jonathan Marc Cohen
  • Patent number: 8133883
    Abstract: An aminocarboxylic acid chelating agent, preferably EDTA, or a salt thereof has been found to be useful for inhibiting particulate formation in piperacillin/tazobactam parenteral combinations. The composition may also contain a buffer, preferably citrate, and optionally an aminoglycoside. The product may be in the form of a frozen composition that can be thawed for use. The product may also be in the form of a cryodesiccated powder that can be reconstituted by addition of an aqueous vehicle to reform a solution.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: March 13, 2012
    Assignee: Pfizer Inc.
    Inventors: Jonathan M. Cohen, Syed M Shah, Christian L. Ofslager, Mahdi B. Fawzi
  • Publication number: 20020048755
    Abstract: A system for developing diagnostic assays, useful in determining whether a particular therapeutic agent will benefit an individual, comprises a continuum of processes that advance diagnostic development while concomitantly benefiting development of the therapeutic agent. This continuum of processes that are dual use, in promoting both diagnostic and drug development, is highly economical and efficient, and creates synergy between pharmaceutical and diagnostic companies.
    Type: Application
    Filed: January 26, 2001
    Publication date: April 25, 2002
    Inventor: Jonathan M. Cohen
  • Patent number: 5427778
    Abstract: Gel formulations containing polypeptide growth factors having human mitogenic or angiogenic activity are provided. The gel formulations are useful for topical or incisional wound healing for cutaneous wounds, in the anterior chamber of the eye and other ophthalmic wound healing. The gel formulations also comprise a water soluble, pharmaceutically or ophthalmically compatible polymeric material for providing viscosity within various ranges determined by the application of the gel. The gel formulations provide controlled release and increased contact time of the growth factor to the wound site.
    Type: Grant
    Filed: November 10, 1992
    Date of Patent: June 27, 1995
    Assignee: Ethicon, Inc.
    Inventors: Amy L. Finkenaur, Jonathan M. Cohen, Shalaby W. Shalaby, Elisabeth A. Sandoval, Rao S. Bezwada, Richard L. Kronenthal
  • Patent number: 4795642
    Abstract: A controlled-release pharmaceutical unit dosage form is provided comprising a gelatin capsule enclosing a solid matrix formed by the cation-assisted gellation of a liquid fill incorporating vegatable gum and a pharmaceutically-active compound, as well as methods for the preparation thereof.
    Type: Grant
    Filed: August 17, 1987
    Date of Patent: January 3, 1989
    Assignee: Pharmacaps, Inc.
    Inventors: Jonathan M. Cohen, Ira R. Berry, Lionel Borkan
  • Patent number: 4708834
    Abstract: A controlled-release pharmaceutical unit dosage form is provided comprising a gelatin capsule enclosing a solid matrix formed by the cation-assisted gellation of a liquid fill incorporating a vegetable gum and a pharmaceutically-active compound, as well as methods for the preparation thereof.
    Type: Grant
    Filed: May 1, 1986
    Date of Patent: November 24, 1987
    Assignee: Pharmacaps, Inc.
    Inventors: Jonathan M. Cohen, Ira R. Berry, Lionel Borkan
  • Patent number: 4591496
    Abstract: A new method for making polymeric systems for the sustained release of macromolecular drugs is described. The method consists of mixing drug and polymer, e.g. ethylene-vinyl acetate copolymer powders below the glass transition temperature of the polymer, and compressing the mixture at a temperature above the glass transition point. The macromolecule is not exposed to organic solvent during the fabrication process. The sustained release and bioactivity of macromolecules is unchanged throughout the pressure casting and release processes.
    Type: Grant
    Filed: January 16, 1984
    Date of Patent: May 27, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: Jonathan M. Cohen, Ronald Siegel, Robert Langer