Patents by Inventor Jonathan M. Diver

Jonathan M. Diver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Integrated portable biological detection system
    Patent number: 7857957
    Abstract: We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imaging. We have also released DNA and RNA from the isolated cells electronically and detected specific marker sequences by DNA amplification followed by electronic hybridization to immobilized capture probes. Efforts towards the construction of a “laboratory-on-a-chip” system are presented which involves the selection of DNA probes, dyes, reagents and prototyping of the fully integrated portable instrument.
    Type: Grant
    Filed: February 5, 2007
    Date of Patent: December 28, 2010
    Assignee: Gamida for Life B.V.
    Inventors: Jing Cheng, Lei Wu, Michael J. Heller, Edward L. Sheldon, Jonathan M. Diver, James P. O'Connell, Dan Smolko, Shila Jalali, David Willoughby
  • Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification an bioelectronic chip technology
    Patent number: 6864071
    Abstract: This invention relates to devices, methods, and compositions of matter for the multiplex amplification and analysis of nucleic acid sequences in a sample using ligation-dependent strand displacement amplification technologies in combination with bioelectronic microchip technology.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: March 8, 2005
    Assignee: Nanogen/Becton Dickinson Partnership
    Inventors: John J. Carrino, Louis O. Gerrue, Jonathan M. Diver
  • Integrated portable biological detection system
    Publication number: 20020155586
    Abstract: We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imaging. We have also released DNA and RNA from the isolated cells electronically and detected specific marker sequences by DNA amplification followed by electronic hybridization to immobilized capture probes. Efforts towards the construction of a “laboratory-on-a-chip” system are presented which involves the selection of DNA probes, dyes, reagents and prototyping of the fully integrated portable instrument.
    Type: Application
    Filed: June 5, 2002
    Publication date: October 24, 2002
    Applicant: Nanogen, Inc.
    Inventors: Jing Cheng, Lei Wu, Michael J. Heller, Edward L. Sheldon, Jonathan M. Diver, James P. O'Connell, Dan Smolko, Shila Jalali, David Willoughby
  • Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
    Publication number: 20020068334
    Abstract: This invention relates to devices, methods, and compositions of matter for the multiplex amplification and analysis of nucleic acid sequences in a sample using ligation-dependent strand displacement amplification technologies in combination with bioelectronic microchip technology.
    Type: Application
    Filed: May 25, 2001
    Publication date: June 6, 2002
    Applicant: NANOGEN, INC. /BECTON DICKINSON PARTNERSHIP
    Inventors: John J. Carrino, Louis O. Gerrue, Jonathan M. Diver
  • Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
    Patent number: 6238868
    Abstract: This invention relates to devices, methods, and compositions of matter for the multiplex amplification and analysis of nucleic acid sequences in a sample using ligation-dependent strand displacement amplification technologies in combination with bioelectronic microchip technology.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: May 29, 2001
    Assignee: Nanogen/Becton Dickinson Partnership
    Inventors: John J. Carrino, Louis O. Gerrue, Jonathan M. Diver