Abstract: Methods are disclosed for treating or preventing fatty liver disease using a CTRP3 polypeptide or functional variant thereof.

Abstract: Methods are disclosed for treating or preventing fatty liver disease using a CTRP3 polypeptide or functional variant thereof.

Abstract: The present invention provides substantially purified peptide portions of adipokine polypeptides, including, for example, C1q/TNF-related protein-12 (CTRP12), a functional homolog or function fragment of CTRP12, and a fusion polypeptide comprising any of the above.

Abstract: Compositions and methods for treatment of obesity and/or Type II diabetes and related metabolic disorders are provided wherein the methods and treatments comprise an effective amount of an isolated and/or purified C1q/TNF-related Protein-9 (CTRP9) or a functional portion thereof, and a pharmaceutically acceptable carrier. Methods of screening for molecules which elevate levels of CTRP9 in vivo are also provided. The present inventors provide the first in vivo evidence linking CTRP9 to regulation of fat metabolism in liver and skeletal muscle via AMPK signaling pathway, and highlight its protective metabolic function in the context of HFD-mediated metabolic insults.

Abstract: Methods and systems are provided for exchanging information between companies in a partnership. One method embodiment includes operatively associating a first company with a transaction directory through a directory management portal. The transaction directory is configured to permit establishment of at least one connection to a translation engine for permitting at least one transaction to occur through the connection. The method also includes connecting at least a second company to the translation engine to permit the transaction to occur between at least the first and second companies. The transaction includes an exchange of information between at least the first and second companies.

Abstract: The present invention provides substantially purified peptide portions of adipokine polypeptides, including, for example, Clq/TNF-related protein-12 (CTRP12), a functional homologue or function fragment of CTRP12, and a fusion polypeptide comprising any of the above.

Abstract: Methods and systems are provided for exchanging information between companies in a partnership. One method embodiment includes operatively associating a first company with a transaction directory through a directory management portal. The transaction directory is configured to permit establishment of at least one connection to a translation engine for permitting at least one transaction to occur through the connection. The method also includes connecting at least a second company to the translation engine to permit the transaction to occur between at least the first and second companies. The transaction includes an exchange of information between at least the first and second companies.

Abstract: Methods and systems are provided for exchanging information between companies in a partnership. One method embodiment includes operatively associating a first company with a transaction directory through a directory management portal. The transaction directory is configured to permit establishment of at least one connection to a translation engine for permitting at least one transaction to occur through the connection. The method also includes connecting at least a second company to the translation engine to permit the transaction to occur between at least the first and second companies. The transaction includes an exchange of information between at least the first and second companies.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and products are disclosed for an edge side assembler. Data is identified that is associated with a common user of a personal digital gateway and of a communications device selected from a plurality of communications devices. Remote data is located that is stored on the selected communications device. The remote data is retrieved and integrated with the data. The integrated data is formatted according to a presentation format associated with the selected communications device. The integrated data is communicated with at least one of the plurality of communications devices.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: A system and method is provided for coordinating network communication between multiple communication devices of a user. A communication session is established with an application. A message is received from the application and sent to one of a plurality of communication devices based at least on a status and an output capability of each of the plurality of communication devices.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: Methods, systems, and apparatuses are disclosed for enabling a virtual personalized network. Communications are established with a personal digital gateway to control access, sharing, security, and/or management of up-to-date personalized data exchanged between or among a plurality of associated communications devices and/or communications networks. The associated communications devices are owned, operated, and/or accessed by a common user.

Abstract: A proxy server identifies data items on a data server that are infrequently changed. The proxy server receives the infrequently changed data items and stores the data item. The proxy server forwards a copy of the data item to other proxy servers. When a request for the data item is received at the proxy server, a message indicating the request has been received is forwarded to the data server. The proxy server communicates instructions to one of the proxy servers to forward the data item to the requesting machine.