Patents by Inventor Jonathan Mark Elkins

Jonathan Mark Elkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identifying a chemical entity which is a hydroxylase modulator
    Patent number: 7778779
    Abstract: A method of identifying, screening, characterising or designing a chemical entity, which mimics or binds to FIH, is described. The method comprises comparing a structural model of FIH with a structural model for said chemical entity, wherein said structural model of FIH is derived from structural factors or structural coordinates determined by subjecting to X-ray diffraction measurements a crystal comprising FIH. Such chemical entities may be used in the treatment of a condition associated with increased or decreased HIF levels or activity.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: August 17, 2010
    Assignee: Isis Innovation Limited
    Inventors: Peter John Ratcliffe, Christopher William Pugh, Christopher Joseph Schofield, Kirsty Sarah Hewitson, Jonathan Mark Elkins