Patents by Inventor Jonathan Martin Large

Jonathan Martin Large has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOUNDS
    Publication number: 20100256143
    Abstract: The invention provides a pyrimidine compound of formula (I): wherein R1 and R2 have any of the values defined herein; or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
    Type: Application
    Filed: April 14, 2008
    Publication date: October 7, 2010
    Inventors: Stewart James Baker, Paul John Goldsmith, Timothy Colin Hancox, Neil Anthony Pegg, Stephen Joseph Shuttleworth, Elsa Amandine Dechaux, Sussie Lerche Krintel, Stephen Price, Jonathan Martin Large, Edward McDonald
  • 2-MORPHOLIN-4-YL-PYRIMIDINES AS PI3K INHIBITORS
    Publication number: 20100210646
    Abstract: The invention provides a pyrimidine compound of formula (I): wherein R1 and R2 have any of the values defined herein; or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
    Type: Application
    Filed: April 14, 2008
    Publication date: August 19, 2010
    Applicants: F. Hoffmann-La Roche AG, The Institute of Cancer Research: Royal Cancer Hos pital
    Inventors: Paul John Goldsmith, Timothy Colin Hancox, Neil Anthony Pegg, Stephen Joseph Shuttleworth, Jonathan Martin Large, Edward McDonald
  • PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE
    Publication number: 20100130496
    Abstract: The invention provides a pyrimidine compound of formula (I): wherein R1, R2, and Y have any of the values defined herein; or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
    Type: Application
    Filed: April 14, 2008
    Publication date: May 27, 2010
    Applicants: F. Hoffmann-La Roche AG, The Institute of Cancer Research: Royal Cancer Hospital
    Inventors: Paul John Goldsmith, Timothy Colin Hancox, Neil Anthony Pegg, Stephen Joseph Shuttleworth, Elsa Amandine Dechaux, Stephen Price, Jonathan Martin Large, Edward McDonald