Patents by Inventor Jonathan Marvin

Jonathan Marvin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically encoded biosensors
    Patent number: 9719992
    Abstract: The present disclosure provides, inter alia, genetically encoded recombinant peptide biosensors comprising analyte-binding framework portions and signaling portions, wherein the signaling portions are present within the framework portions at sites or amino acid positions that undergo a conformational change upon interaction of the framework portion with an analyte.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: August 1, 2017
    Assignees: Howard Hughes Medical Institute, Brigham & Woman's Hospital, Inc.
    Inventors: Jonathan Marvin, Loren Looger, Richard T. Lee, Eric Schreiter
  • GENETICALLY ENCODED BIOSENSORS
    Publication number: 20150111222
    Abstract: The present disclosure provides, inter alia, genetically encoded recombinant peptide biosensors comprising analyte-binding framework portions and signaling portions, wherein the signaling portions are present within the framework portions at sites or amino acid positions that undergo a conformational change upon interaction of the framework portion with an analyte.
    Type: Application
    Filed: August 8, 2012
    Publication date: April 23, 2015
    Applicant: HOWARD hUGHES MEDICAL INSTITUTE
    Inventors: Jonathan Marvin, Loren Looger, Richard T. Lee, Eric Schreiter
  • ANTIBODY VARIANTS WITH FASTER ANTIGEN ASSOCIATION RATES
    Publication number: 20070037255
    Abstract: Antibody variants with faster antigen association rates are disclosed. The antibody variants have one or more amino acid alteration(s) in or adjacent to at least one hypervariable region thereof which increase charge complementarity between the antibody variant and an antigen to which it binds.
    Type: Application
    Filed: October 2, 2006
    Publication date: February 15, 2007
    Inventors: Henry Lowman, Jonathan Marvin
  • Polypeptide variants with altered effector function
    Publication number: 20060067930
    Abstract: The invention provides polypeptides having IgG Fc regions with amino acid modifications that result in the polypeptides exhibiting altered Fc effector functions.
    Type: Application
    Filed: August 19, 2005
    Publication date: March 30, 2006
    Applicant: Genentech, Inc.
    Inventors: Camellia Adams, Samantha Lien, Henry Lowman, Jonathan Marvin, Yu-Ju Meng