Patents by Inventor JONATHAN MATTHEWS

JONATHAN MATTHEWS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12646034
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Grant
    Filed: September 5, 2024
    Date of Patent: June 2, 2026
    Assignee: IODINE SOFTWARE, LLC
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Publication number: 20260034229
    Abstract: Aspects of the disclosure relate to compositions and methods for reducing toxicity of a cytotoxic agent comprising administering an antigen-binding protein conjugated to a protection molecule.
    Type: Application
    Filed: October 17, 2025
    Publication date: February 5, 2026
    Inventors: Savas TAY, Jonathan MATTHEWS, Betul CELIKER
  • Publication number: 20250372243
    Abstract: A prediction cycle controller queries a database for patient visits that are eligible for admit status prediction (ASP) and extracts, from the patient visits eligible for the ASP, ASP features and major diagnosis category (MDC) prediction features for each of the patient visits. The ASP features include observations of prediction-eligible patients of a healthcare provider. The MDC prediction features include data points for determining a MDC. The ASP features are provided to an admit status predictor which examines, utilizing a machine learning model, the observations of the prediction-eligible patients and generates an ASP for each prediction-eligible patient. The MDC prediction features are provided to an MDC predictor which examines the MDC prediction features and the ASP thus generated by the admit status predictor for each prediction-eligible patient and generates a MDC prediction (MDCP). The ASP and the MDCP are then presented, via a user interface, on a user device.
    Type: Application
    Filed: May 28, 2025
    Publication date: December 4, 2025
    Inventors: W. Lance Eason, Sawyer Graeber, Jonathan Matthews, Brandon Vecchio, Nicholas Davis, Greg Hennigan
  • Publication number: 20240428194
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Application
    Filed: September 5, 2024
    Publication date: December 26, 2024
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Home, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 12112296
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Grant
    Filed: August 16, 2023
    Date of Patent: October 8, 2024
    Assignee: IODINE SOFTWARE, LLC
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 11955213
    Abstract: In clinical documentation, mere documentation of a condition in a patient's records may not be enough. To be considered sufficiently documented, the patient's record needs to show that no documentation drop-offs (DDOs) have occurred over the course of the patient's stay. However, DDOs can be extremely difficult to detect. To solve this problem, the invention trains time-sensitive deep learning (DL) models on a per condition basis using actual and/or synthetic patient data. Utilizing an ontology, grouped concepts can be generated on the fly from real-time hospital data and used to generate time-series data that can then be analyzed by trained time-sensitive DL models to determine whether a DDO for a condition has occurred during the stay. Non-time-sensitive models can be used to detect all the conditions documented during the stay. Outcomes from the models can be compared to determine whether to notify a user that a DDO has occurred.
    Type: Grant
    Filed: February 13, 2023
    Date of Patent: April 9, 2024
    Assignee: IODINE SOFTWARE, LLC
    Inventors: Jonathan Matthews, W. Lance Eason, William Chan, Michael Kadyan, Frances Elizabeth Jurcak, Timothy Paul Harper
  • Publication number: 20230394437
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Application
    Filed: August 16, 2023
    Publication date: December 7, 2023
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 11775932
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: October 3, 2023
    Assignee: Iodine Software, LLC
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Publication number: 20230197221
    Abstract: In clinical documentation, mere documentation of a condition in a patient's records may not be enough. To be considered sufficiently documented, the patient's record needs to show that no documentation drop-offs (DDOs) have occurred over the course of the patient's stay. However, DDOs can be extremely difficult to detect. To solve this problem, the invention trains time-sensitive deep learning (DL) models on a per condition basis using actual and/or synthetic patient data. Utilizing an ontology, grouped concepts can be generated on the fly from real-time hospital data and used to generate time-series data that can then be analyzed by trained time-sensitive DL models to determine whether a DDO for a condition has occurred during the stay. Non-time-sensitive models can be used to detect all the conditions documented during the stay. Outcomes from the models can be compared to determine whether to notify a user that a DDO has occurred.
    Type: Application
    Filed: February 13, 2023
    Publication date: June 22, 2023
    Inventors: Jonathan Matthews, W. Lance Eason, William Chan, Michael Kadyan, Frances Elizabeth Jurcak, Timothy Paul Harper
  • Patent number: 11581075
    Abstract: In clinical documentation, mere documentation of a condition in a patient's records may not be enough. To be considered sufficiently documented, the patient's record needs to show that no documentation drop-offs (DDOs) have occurred over the course of the patient's stay. However, DDOs can be extremely difficult to detect. To solve this problem, the invention trains time-sensitive deep learning (DL) models on a per condition basis using actual and/or synthetic patient data. Utilizing an ontology, grouped concepts can be generated on the fly from real-time hospital data and used to generate time-series data that can then be analyzed by trained time-sensitive DL models to determine whether a DDO for a condition has occurred during the stay. Non-time-sensitive models can be used to detect all the conditions documented during the stay. Outcomes from the models can be compared to determine whether to notify a user that a DDO has occurred.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: February 14, 2023
    Assignee: Iodine Software, LLC
    Inventors: Jonathan Matthews, W. Lance Eason, William Chan, Michael Kadyan, Frances Elizabeth Jurcak, Timothy Paul Harper
  • Publication number: 20220343280
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Application
    Filed: July 11, 2022
    Publication date: October 27, 2022
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 11423356
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: August 23, 2022
    Assignee: Iodine Software, LLC
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Publication number: 20210151144
    Abstract: In clinical documentation, mere documentation of a condition in a patient's records may not be enough. To be considered sufficiently documented, the patient's record needs to show that no documentation drop-offs (DDOs) have occurred over the course of the patient's stay. However, DDOs can be extremely difficult to detect. To solve this problem, the invention trains time-sensitive deep learning (DL) models on a per condition basis using actual and/or synthetic patient data. Utilizing an ontology, grouped concepts can be generated on the fly from real-time hospital data and used to generate time-series data that can then be analyzed by trained time-sensitive DL models to determine whether a DDO for a condition has occurred during the stay. Non-time-sensitive models can be used to detect all the conditions documented during the stay. Outcomes from the models can be compared to determine whether to notify a user that a DDO has occurred.
    Type: Application
    Filed: December 21, 2020
    Publication date: May 20, 2021
    Inventors: Jonathan Matthews, W. Lance Eason, William Chan, Michael Kadyan, Frances Elizabeth Jurcak, Timothy Paul Harper
  • Patent number: 10886013
    Abstract: In clinical documentation, mere documentation of a condition in a patient's records may not be enough. To be considered sufficiently documented, the patient's record needs to show that no documentation drop-offs (DDOs) have occurred over the course of the patient's stay. However, DDOs can be extremely difficult to detect. To solve this problem, the invention trains time-sensitive deep learning (DL) models on a per condition basis using actual and/or synthetic patient data. Utilizing an ontology, grouped concepts can be generated on the fly from real-time hospital data and used to generate time-series data that can then be analyzed by trained time-sensitive DL models to determine whether a DDO for a condition has occurred during the stay. Non-time-sensitive models can be used to detect all the conditions documented during the stay. Outcomes from the models can be compared to determine whether to notify a user that a DDO has occurred.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: January 5, 2021
    Assignee: IODINE SOFTWARE, LLC
    Inventors: Jonathan Matthews, W. Lance Eason, William Chan, Michael Kadyan, Frances Elizabeth Jurcak, Timothy Paul Harper
  • Publication number: 20200356952
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Application
    Filed: July 27, 2020
    Publication date: November 12, 2020
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 10733566
    Abstract: A clinical documentation improvement (CDI) smart scoring method may include predicting, via per-condition diagnosis machine learning (ML) models and based on clinical evidence received by a system, a probability that a medical condition is under-documented and, via per-condition documentation ML models and based on documentation received by the system, a probability that a medical condition is over-documented. The under- and over-documentation scores are combined in view of special indicators and queryability factors, which can also be evaluated using ML query prediction models, to generate an initial CDI score. This CDI score can be further adjusted, if necessary or desired, to account for factors such as length of stay, payer, patient location, CDI review timing, etc. The final CDI score can be used to prioritize patient cases for review by CDI specialists to quickly and efficiently identify meaningful CDI opportunities.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: August 4, 2020
    Assignee: Iodine Software, LLC
    Inventors: William Chan, W. Lance Eason, Timothy Harper, Bryan Horne, Michael Kadyan, Jonathan Matthews, Joshua Toub
  • Patent number: 9952482
    Abstract: There is presented an optical apparatus comprising first and second photon pair sources configured to convert at least one pump light photon into a first and second correlated signal and idler photon pairs. In one example, the apparatus is configured to use one of the signal and idler photons from the first correlated photon pair for controlling the conversion of the pump light photon in the second photon pair source. The apparatus may configured such that, at least one of the signal and idler photons from the first correlated photon pair is output from the first photon pair source onto an optical path wherein at least one of the signal and idler photons from the second correlated photon pair is output from the second photon pair source onto the optical path. A method is also provided for outputting one or more photons using the optical apparatus.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: April 24, 2018
    Assignee: The University of Bristol
    Inventors: Terence Rudolph, Mark Thompson, Jonathan Matthews, Damien Bonneau
  • Publication number: 20170075190
    Abstract: There is presented an optical apparatus comprising first and second photon pair sources configured to convert at least one pump light photon into a first and second correlated signal and idler photon pairs. In one example, the apparatus is configured to use one of the signal and idler photons from the first correlated photon pair for controlling the conversion of the pump light photon in the second photon pair source. The apparatus may configured such that, at least one of the signal and idler photons from the first correlated photon pair is output from the first photon pair source onto an optical path wherein at least one of the signal and idler photons from the second correlated photon pair is output from the second photon pair source onto the optical path. A method is also provided for outputting one or more photons using the optical apparatus.
    Type: Application
    Filed: September 9, 2016
    Publication date: March 16, 2017
    Inventors: TERENCE RUDOLPH, MARK THOMPSON, JONATHAN MATTHEWS, DAMIEN BONNEAU