Patents by Inventor Jonathan Moseley

Jonathan Moseley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF BROMODOMAIN INHIBITOR
    Publication number: 20230128975
    Abstract: The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.
    Type: Application
    Filed: December 14, 2022
    Publication date: April 27, 2023
    Applicant: Celgene Quanticel Research, Inc.
    Inventors: John Fitzgerald Traverse, Kelvin Hin-Yeong Yong, Antonio Christian Ferretti, Hekla Alite, Jonathan Moseley, Antonio Maria Ruda, David Primer, Steven Philp
  • Process for the preparation of bromodomain inhibitor
    Patent number: 11566004
    Abstract: The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: January 31, 2023
    Assignee: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: John Fitzgerald Traverse, Kelvin Hin-Yeong Yong, Antonio Christian Ferretti, Hekla Alite, Jonathan Moseley, Antonio Maria Ruda, David Primer, Steven Philp
  • PROCESS FOR THE PREPARATION OF BROMODOMAIN INHIBITOR
    Publication number: 20220064121
    Abstract: The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.
    Type: Application
    Filed: July 23, 2019
    Publication date: March 3, 2022
    Applicant: Celgene Quanticel Research, Inc.
    Inventors: John Fitzgerald TRAVERSE, Kelvin Hin-Yeong Yong, Antonio Christian Ferretti, Hekla Alite, Jonathan Moseley, Antonio Maria Ruda, David Primer, Steven Philp
  • Method
    Patent number: 7012145
    Abstract: Process for preparing 3-[(4S)-5-oxo-2-(trifluoromethyl)-1,4,5,6,7,8-hexahydroquinolin-4-yl]benzonitrile, pharmaceutical compositions containing the compound and methods of treatment using the same.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: March 14, 2006
    Assignee: Astrazeneca AB
    Inventors: Andrew Jones, Jonathan Moseley, Ian Patel, Evan Snape, Maureen Young
  • Method
    Publication number: 20050080104
    Abstract: Process for preparing 3-[(4S)-5-oxo-2-(trifluoromethyl)-1,4,5,6,7,8-hexahydroquinolin-4-yl]benzonitrile, pharmaceutical compositions containing the compound and methods of treatment using the same.
    Type: Application
    Filed: January 23, 2003
    Publication date: April 14, 2005
    Inventors: Andrew Jones, Jonathan Moseley, Ian Patel, Evan Snape, Maureen Young