Abstract: The present invention provides methods for accelerating orthodontic tooth movement and for treating relapse. The orthodontic methods comprise applying force to reposition teeth and administering a tissue remodeling and/or an angiogenic substance to the periodontal tissue surrounding the teeth to be moved. The substance may be delivered before, during, or after the teeth are moved, and the substance may be selectively applied only to those teeth undergoing movement at any particular time. The substance may be applied from the dental repositioning appliance or may be applied separately, either locally or systemically. Orthodontic kits are also encompassed by the instant invention.

Abstract: An apparatus, system, and method of removing removable tooth positioning appliances, such as aligners, from the teeth of a patient. In one aspect, the invention is an apparatus for removing a removable tooth positioning appliance from teeth of a patient comprising: a handle portion; a member extending from the handle portion and having a distal end; and an engagement block having a tapered edge for engaging an edge of the tooth positioning appliance, the engagement block protruding from the member at or near the distal end.