Patents by Inventor Jonathan P. Duvick
Jonathan P. Duvick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7611897Abstract: New fumonisin detoxifying or fumonisin-derivative detoxifying homologues (both nucleic acids and proteins) are provided. Compositions which include these new proteins, recombinant cells, antibodies to the new homologues, and methods of using the homologues are also provided.Type: GrantFiled: June 21, 2004Date of Patent: November 3, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: Ranjini Chatterjee, Jonathan P. Duvick, James English
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Patent number: 7241934Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera and Rhinocladiella atrovirens. The polynucleotides may be mutated to remove glycosylation sites and cysteine residues. Additionally, the present invention provides recombinant expression cassettes, host cells, transgenic plants, and transgenic seed. The present invention also provides for polynucleotides containing both APAO and a fumonisin esterase. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and eukaryotic systems, methods for detecting fumonisins, and methods for identifying transformed plant cells. Methods for degrading fungal toxins in plants, grain, grain processing, silage, food crops and in animal feed are also disclosed.Type: GrantFiled: December 22, 2003Date of Patent: July 10, 2007Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Aragula Gururaj Rao, Oswald R. Crasta, Otto Folkerts
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Patent number: 6987212Abstract: The present invention provides transformed plants comprising a polynucleotide enconding amino polyol amine oxidase (APAO ) from Exophiala spinifera and a method of expressing APAO transgenic plants and seeds. In this way, transgenic plant can be produced having fumonisin degrading capability, as well as with the capability of producing the degrading enzymes.Type: GrantFiled: July 22, 2003Date of Patent: January 17, 2006Assignees: Pioneer Hi-Bred International, Inc., Curagen CorporationInventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald R. Crasta, Otto Folkerts
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Patent number: 6943279Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera and Rhinocladiella airovirens. The polynucleotides may be mutated to remove glycosylation sites and cysteine residues. Additionally, the present invention provides recombinant expression cassettes, host cells, transgenic plants, and transgenic seed. The present invention also provides for polynucleotides containing both APAO and a fumonisin esterase. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and eukaryotic systems, methods for detecting fumonisins, and methods for identifying transformed plant cells. Methods for degrading fungal toxins in plants, grain, grain processing, silage, food crops and in animal feed are also disclosed.Type: GrantFiled: September 8, 2000Date of Patent: September 13, 2005Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Aragula Gururaj Rao, Oswald R. Crasta, Otto Folkerts
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Patent number: 6921847Abstract: Methods and nucleotide sequences encoding maize lipoxygenase proteins for modulating defense response are provided. The nucleotide sequences can be used in expression cassettes for modulating plant defense response. Transformed plants, plant cells and seed are also provided.Type: GrantFiled: April 25, 2002Date of Patent: July 26, 2005Assignee: Pioneer Hi-Bred International, Inc.Inventors: Pedro A. Navarro Acevedo, Jonathan P. Duvick, Mikhailo V. Kolomiets, Carl R. Simmons
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Patent number: 6835569Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera. Additionally, the polynucleotide encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems.Type: GrantFiled: January 26, 2001Date of Patent: December 28, 2004Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald Crasta, Otto Folkerts
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Publication number: 20040168212Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera. Additionally, the polynucleotide encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems. Methods for detoxification in grain, grain processing, silage, food crops and in animal feed and rumen microbes are also disclosed.Type: ApplicationFiled: July 22, 2003Publication date: August 26, 2004Applicants: Pioneer Hi-Bred International, Inc., CuraGen Corp.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald R. Crasta, Otto Folkerts
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Patent number: 6737562Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinfera and Rhinocladiella atrovirens. Additionally, the polynucleotides encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium. Plants can be regenerated from the transformed plant cells.Type: GrantFiled: January 26, 2001Date of Patent: May 18, 2004Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox
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Patent number: 6709865Abstract: Methods and compositions for modulating development and defense response are provided. Nucleotide sequences encoding a LOX protein are provided. Nucleotide sequences comprising the LOX promoter are also provided. The sequences can be used in expression cassettes for modulating development, developmental pathways, and the plant defense response. Transformed plants, plant cells, tissues, and seed are also provided.Type: GrantFiled: November 16, 2000Date of Patent: March 23, 2004Assignee: Pioneer Hi-Bred International, Inc.Inventors: Dennis L. Bidney, Jonathan P. Duvick, Carol Hendrick, Xu Hu, Guihua Lu, Oswald R. Crasta
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Patent number: 6667427Abstract: Compositions and methods to aid in protecting plants from invading pathogenic organisms are provided. The compositions of the invention comprise anti-pathogenic nucleotide sequences, including their promoters, and polypeptides encoded by the anti-pathogenic nucleic acid sequences. The compositions find use in methods for reducing or eliminating damage to plants caused by plant pathogens. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.Type: GrantFiled: October 10, 2000Date of Patent: December 23, 2003Assignee: Pioneer Hi-Bred International, Inc.Inventors: Zhangmeng Bao, Jonathan P. Duvick, Xu Hu, Guihua Lu
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Publication number: 20030166855Abstract: Methods and compositions for modulating development and defense response are provided. Nucleotide sequences encoding maize lipoxygenase proteins and a lipoxygenase gene promoter region are provided. The sequences can be used in expression cassettes for modulating development, developmental pathways, and the plant defense response. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: April 25, 2002Publication date: September 4, 2003Applicant: Pioneer Hi-Bred International, Inc.Inventors: Pedro A. Navarro Acevedo, Jonathan P. Duvick, Mikhailo V. Kolomiets, Carl R. Simmons
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Publication number: 20030126636Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera. Additionally, the polynucleotide encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems. Methods for detoxification in grain, grain processing, silage, food crops and in animal feed and rumen microbes are also disclosed.Type: ApplicationFiled: January 26, 2001Publication date: July 3, 2003Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald R. Crasta, Otto Folkerts
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Patent number: 6555732Abstract: The present invention provides methods and compositions relating to creating or enhancing disease resistance in plants. The invention provides isolated maize Rac nucleic acids and their encoded proteins that are involved in the altering the disease resistance pathway in plants, increasing transformation efficiency, inducing programmed cell death, and modulating the oxidative burst in a plant. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: GrantFiled: September 8, 1999Date of Patent: April 29, 2003Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Yogesh Kumar Sharma
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Publication number: 20030056245Abstract: New fumonisin detoxifying or fumonisin-derivative detoxifying homologues (both nucleic acids and proteins) are provided. Compositions which include these new proteins, recombinant cells, antibodies to the new homologues, and methods of using the homologues are also provided.Type: ApplicationFiled: February 6, 2002Publication date: March 20, 2003Applicant: Maxygen, Inc.Inventors: Ranjini Chatterjee, Jonathan P. Duvick, James English
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Publication number: 20030028921Abstract: Methods and compositions for modulating development and defense response are provided. Nucleotide sequences encoding maize BTL proteins are provided. The sequence can be used in expression cassettes for antimicrobial resistance, modulating development, developmental pathways, and defense response. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: July 24, 2002Publication date: February 6, 2003Applicant: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Pedro A. Navarro Acevedo, Carl R. Simmons
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Publication number: 20020049993Abstract: Methods and compositions for modulating development and defense response are provided. Nucleotide sequences encoding maize rhoGAP proteins are provided. The sequence can be used in expression cassettes for modulating development, developmental pathways, and defense response. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: June 1, 2001Publication date: April 25, 2002Applicant: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Xu Hu, Guihua Lu
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Patent number: 6211435Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera. Additionally, the polynucleotide encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems. Methods for detoxification in grain, grain processing, silage, food crops and in animal feed and rumen microbes are also disclosed.Type: GrantFiled: July 12, 1999Date of Patent: April 3, 2001Assignees: Pioneer Hi-Bred International, Inc., CuraGen CorporationInventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox, Oswald R. Crasta, Otto Folkerts
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Patent number: 6211434Abstract: The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated from Exophiala spinifera and Rhinocladiella atrovirens. Additionally, the polynucleotides encoding for the APAO enzyme can be used to transform plant cells normally susceptible to Fusarium or other toxin-producing fungus infection. Plants can be regenerated from the transformed plant cells. Additionally, the present invention provides for expressing both APAO and a fumonisin esterase in a transgenic plant. In this way, a transgenic plant can be produced with the capability of degrading fumonisin, as well as with the capability of producing the degrading enzymes. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and non-plant eukaryotic systems. Methods for detoxification in grain, grain processing, silage, food crops and in animal feed and rumen microbes are also disclosed.Type: GrantFiled: July 12, 1999Date of Patent: April 3, 2001Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Jacob T. Gilliam, Joyce R. Maddox
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Patent number: 6198020Abstract: Compositions and methods to aid in protecting the plant from invading pathogenic organisms are provided. The compositions of the invention comprise genes that influence the levels of nitric oxide in plant cells. Such genes include those encoding nitric oxide synthase (iNOS) as well as natural resistance-associated macrophage proteins (NRAMP) and NRAMP homologues. A pathogen inducible promoter or alternatively a constitutive, preferably a weak constitutive, promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.Type: GrantFiled: February 24, 1999Date of Patent: March 6, 2001Assignee: Pioneer Hi-Bred International, Inc.Inventors: Benjamin A. Bowen, Jonathan P. Duvick, Carl R. Simmons
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Patent number: 5905187Abstract: CMIII, a small, basic maize seed peptide has been found to have antimicrobial properties. In a preferred embodiment, plant resistance to diseases caused by plant pathogens which are susceptible to CMIII is produced by inserting into the cells of a plant a gene whose expression causes production CMIII in antimicrobial amounts.Type: GrantFiled: March 19, 1997Date of Patent: May 18, 1999Assignee: Pioneer Hi-Bred International, Inc.Inventors: Jonathan P. Duvick, Tracy A. Rood, Aragula G. Rao