Patents by Inventor Jonathan P. McMullen

Jonathan P. McMullen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL SYNTHETIC PATHWAY TO BELZUTIFAN
    Publication number: 20240010613
    Abstract: The disclosure provides a novel process and synthetic intermediates for making belzutifan, a HIF-2a inhibitor, useful for the treatment of certain VHL-related indications and cancer.
    Type: Application
    Filed: July 3, 2023
    Publication date: January 11, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Daniel A. DiRocco, Jackson Kenai Blender Cahn, Wai Ling Cheung-Lee, Stephanie W. Chun, J. Caleb Hethcox, Heather Claire Johnson, Jungchul Kim, Joshua N. Kolev, Birgit Kosjek, Diane Le, Scott D. McCann, John McIntosh, Jonathan P. McMullen, Jeffrey C. Moore, William Morris, Juan Esteban Velasquez Velez, Matthew S. Winston, Victoria Zhang, Yong-Li Zhong
  • Immobilized transaminases and process for making and using immobilized transaminase
    Patent number: 9523107
    Abstract: The invention is directed to immobilized transaminases and methods of making and using them.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: December 20, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Matthew D. Truppo, Michel Journet, Hallena Strotman, Jonathan P. McMullen, Shane T. Grosser
  • IMMOBILIZED TRANSAMINASES AND PROCESS FOR MAKING AND USING IMMOBILIZED TRANSAMINASE
    Publication number: 20150368682
    Abstract: The invention is directed to immobilized transaminases and methods of making and using them.
    Type: Application
    Filed: February 24, 2014
    Publication date: December 24, 2015
    Inventors: Matthew D. Truppo, Michel Journet, Hallena Strotman, Jonathan P. McMullen, Shane T. Grosser
  • Methods for handling solids in microfluidic systems
    Patent number: 8763623
    Abstract: Systems and methods related to handling solids in microfluidic systems are generally described. Many of the systems and methods described herein address the need to inhibit the formation of blockages in microfluidic channels.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: July 1, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Ryan L. Hartman, John R. Naber, Nikolay Zaborenko, Jonathan P. McMullen, Klavs F. Jensen
  • SYSTEMS AND METHODS FOR HANDLING SOLIDS IN MICROFLUIDIC SYSTEMS
    Publication number: 20110126914
    Abstract: Systems and methods related to handling solids in microfluidic systems are generally described. Many of the systems and methods described herein address the need to inhibit the formation of blockages in microfluidic channels.
    Type: Application
    Filed: November 5, 2010
    Publication date: June 2, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Ryan L. Hartman, John R. Naber, Nikolay Zaborenko, Jonathan P. McMullen, Klavs F. Jensen