Patents by Inventor Jonathan Paul Graham

Jonathan Paul Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Processes
    Publication number: 20120220779
    Abstract: The present invention provides processes useful for preparing 5-lipoxygenase activating protein (FLAP) inhibitors and their intermediates. In particular, processes for preparing 3-[3-(tert-butylsulfanyl)-1-[4-(6-ethoxy-pyridin-3-yl)benzyl]-5-(5-methyl-pyridin-2-yl-methoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid, the anhydrous Form C polymorph of sodium 3-[3-(tert-butylsulfanyl)-1-[4-(6-ethoxy-pyridin-3-yl)benzyl]-5-(5-methyl-pyridin-2-yl-methoxy)-1H-indol-2-yl]-2,2-dimethyl-propionate, and intermediates useful in said processes are provided.
    Type: Application
    Filed: November 2, 2010
    Publication date: August 30, 2012
    Inventors: Claire Frances Crawford, Sandrine Garcia, Jonathan Paul Graham, Sandra Jane Harling, Nicholas Paul Henley, Stephen Andrew Hermitage, John Howard Hutchinson, Trevor Raymond Keel, Andrew Kennedy, Andrew McMurtrie Mason, Mark Simon Scott, Neil Michael Smith, Nicholas Simon Stock, Yuichi Tateno, Leontine Saskia Trouw, Peter Graham Turner, Christopher John Wallis, Robert David Willacy
  • HEMI-FUMARATE SALT OF A 1,3,4-THIADIAZOLYL DERIVATIVE AS MODULATOR OF THE SPHINGOSINE 1-PHOSPHATE RECEPTOR
    Publication number: 20110034524
    Abstract: The invention relates to the compound (2S)-2-amino-2-{5-[4-(octyloxy)-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}-1-propanol hemi-fumarate, processes for its preparation, pharmaceutical compositions containing them and its use in the treatment of conditions or disorders which are mediated via the S1P1 receptor.
    Type: Application
    Filed: February 3, 2009
    Publication date: February 10, 2011
    Applicant: Glaxo Group Limited
    Inventors: Michael Simon Anson, Caroline Jane Day, Jonathan Paul Graham, Leanda Jane Kindon, Grahame Robert Woollam