Abstract: Methods of treating conditions related to lung disease using an antigen binding protein specific for the Jagged1 polypeptide are provided.

Abstract: A powder composition for use in additive manufacturing, related metal-based particles, related methods and related consolidated part. The composition consisting of metal-based particles and a remainder representing at most 10 wt % of a total weight of the composition, which can be at least one of a ceramic, a lubricant and a binder. The metal-based particles are highly spherical and can be considered fines-free. More particularly, less than 8,000,000 of the metal-based particles per gram of the metal-based particles have a diameter smaller than or equal to 15 ?m; and the metal-based particles have at least one of an average aspect ratio greater than or equal to 0.95; an average roundness greater than or equal to 0.95; and an average Krumbein sphericity greater than or equal to 0.95.

Abstract: Methods of treating conditions related to lung disease using an antigen binding protein specific for the Jagged1 polypeptide are provided.

Abstract: A system, apparatus, and method for controlling operation of a drilling machine includes determining a rock-coal transition and enabling both the real-time control of the blasthole drilling operation of the drilling machine responsive to the determination of the rock-coal transition or using the rock-coal transition information for mine planning in a post-processing application. Such controlling can include stopping the drilling operation of the drilling machine prior to or upon reaching the coal. Mine planning allows for more efficient removal of the exploitable coal. The determining and controlling can be performed in real time based on specialized transformation of Monitor-While Drilling (MWD) data from one or more sensors of the drilling machine while the drilling machine is drilling. The mine planning application is based on processing the Monitor-While Drilling (MWD) data from one or more sensors of the drilling machine after the drilling machine has completed the drilling of a blasthole or blastholes.

Abstract: A system, apparatus, and method for determining intact versus fractured rock zones based on performance monitoring of an electric drilling machine when drilling a blasthole. The determination can be based on a calculation of compensated blastability index (“CBI”) values using transformed performance monitoring data collected in real-time as the drilling machine drills the blasthole.

Abstract: An apparatus and method for dynamic and reversible patterning of mask layers and manipulation and redistribution of energy sources such as laser beams. An embodiment of the present invention provides an apparatus including a mirror-like thin film comprising a front surface and a back surface configured to reflect a laser beam; a layer of a mask material on top of the front surface of the mirror-like thin film, wherein the mask material is transparent to the laser beam and is dewetted by a heat source to create a height profile in the mask material.

Abstract: The disclosure provides a method a method for generating a heterogeneous carbon-bonded material using an activated carbon support a solution comprising a material precursor and a chemical agent. The material precursor is typically a salt such as SnCl2, and the chemical agent is a substance which thermally decomposes to generate reducing gases. The mixture is heated in an inert, nonreactive atmosphere to generate the reducing gases and remove surface groups from the carbon support, allowing material such as metal from the material precursor to nucleate and directly bond to the sites. The method typically utilizes high specific surface area carbon and may produce a plurality of metal particles having an average diameter of less than about 20 nm dispersed on and strongly bonded to the underlying carbon support.

Abstract: The disclosure provides a method for generating a solid metal object. Initially, a reductant material and a metal precursor particle mixture are arranged in a high temperature furnace that is filled with a chemically inert atmosphere. A temperature of the high temperature furnace is held above the decomposition temperature of the reductant but below a melting point of the metal precursor particle mixture for a predetermined duration to generate the solid metal object. At this stage, the generated metal object is cooled in the inert atmosphere.

Abstract: A composite material with enhanced electrical conductivity. The composite material includes two distinct phases. The first distinct phase is an excluded volume phase that includes an electrical insulator. The second distinct phase, a conductor phase, is a composite including an electrically insulating matrix and an embedded conductor phase that has sufficient concentration to exceed a percolation threshold within the conductor phase.

Abstract: A system and method of providing metal comprising objects via additive manufacturing techniques using an RES mixture. The RES process mixes a precursor compound and a chemical agent which thermally decomposes to form typically CO, H2, NHx, or some other reducing agent. Using the RES mixture, the additive manufacturing device reproduces an object from a sliced object model file layer-by-layer. Heat is applied to the patterned RES mixture to thermally decompose the chemical agent and reduce the precursor compound to a reduced metal species. This heating and reduction transforms the RES mixture from a general paste having little to no shear strength to an solid form exhibiting a much greater shear strength, allowing layer-by-layer generation of 3D object components.

Abstract: A parallel plate capacitor including a cathode core that further includes a pair of parallel electrodes and a dielectric material layer positioned between the pair of parallel electrodes. The capacitor also includes a dielectric liquid medium, where the cathode core is at least partially submerged in the dielectric liquid medium.

Abstract: The disclosure provides a method for generating a metallic coating on a substrate using a mixture comprising a precursor compound typically of chromium oxide, a chemical agent typically comprising NHz, and an inert transport fluid. The precursor compound and chemical agent are generally in the form of particulates having mean diameters less than about 100 microns, and the transport fluid is present in an amount sufficient to facilitate application of the mixture to a substrate. The mixture is applied to a substrate and the coated substrate is heated to a temperature exceeding the decomposition temperature of the chemical agent, generating a reducing gas typically comprising CO, Hx, and/or NHx. In a particular embodiment, the precursor compound is CrO2, Cr3O4, CrO, or mixtures thereof, the chemical agent is urea, and the coated substrate is placed in a reactor having an inert atmosphere and subjected to a temperature of about 700° C. for about 5 minutes while maintaining an inert gas flow through the reactor.

Abstract: An apparatus and method for dynamic and reversible patterning of mask layers and manipulation and redistribution of energy sources such as laser beams. An embodiment of the present invention provides an apparatus including a mirror-like thin film comprising a front surface and a back surface configured to reflect a laser beam; a layer of a mask material on top of the front surface of the mirror-like thin film, wherein the mask material is transparent to the laser beam and is dewetted by a heat source to create a height profile in the mask material.

Abstract: Methods of treating conditions related to lung disease using an antigen binding protein specific for the Jagged1 polypeptide are provided.

Abstract: This disclosure describes processes for using biomass feedstock to produce a fermented product and co-products. The process includes washing the biomass feedstock, pretreating the washed feedstock, hydrolysis and fermentation of the pretreated feedstock(s) to produce cellulosic biofuel and co-products. The processes may also include yeast hydrolysis and aerobic propagation.

Abstract: A capacitor having first and second electrodes and a scaffold dielectric where at least one electrode comprises an electrically and ionically conducting material. The scaffold dielectric comprises an insulating material with a plurality of longitudinal channels extending across the dielectric and filled with a liquid comprising cations and anions. The plurality of longitudinal channels are substantially parallel and the liquid within the longitudinal channels generally has an ionic strength of at least 0.1. Capacitance results from the migrations of positive and negative ions in the confined liquid in response to an applied electric field. A method of supplying power to a load using the capacitor and a method of making the capacitor is additionally disclosed.

Abstract: A method for lithographic patterning of thin films. A thin film is deposited on a substrate and the film is exposed to optical energy from a focused laser to induce a thermal gradient in the film by optical absorption. The film is softened through a melting or glass transition process and the thermal gradient induces a directional dewetting down the thermal gradient. The invention permits developer free positive tone lithography by thermal direct write and also metrology of the thin film by the morphology of the resultant features.

Abstract: A capacitor having first and second electrodes and a scaffold dielectric. The scaffold dielectric comprises an insulating material with a plurality of longitudinal channels extending across the dielectric and filled with a dielectric paste comprising a porous material and an ion-comprising liquid within the pores of the porous material. The plurality of longitudinal channels are substantially parallel and the liquid comprising the dielectric paste generally has an ionic strength of at least 0.1. Capacitance results from the migrations of positive and negative ions in the confined liquid in response to an applied electric field. A method of supplying power to a load using the capacitor and a method of making the capacitor is additionally disclosed.

Abstract: A class of materials is provided that has dielectric constants greater than 105. The super dielectric materials (SDM) can be generated readily from common, inexpensive materials. Various embodiments include a porous, electrically insulating material, such as high surface area powders of silica or titania, mixed with a liquid containing a high concentration of ionic species. In some embodiments, high surface area alumina powders, loaded to the incipient wetness point with a solution of boric acid dissolved in water, have dielectric constants greater than 4×108.

Abstract: A capacitor having first and second electrodes and a scaffold dielectric. The scaffold dielectric comprises an insulating material with a plurality of longitudinal channels extending across the dielectric and filled with a liquid comprising cations and anions. The plurality of longitudinal channels are substantially parallel and the liquid within the longitudinal channels generally has an ionic strength of at least 0.1. Capacitance results from the migrations of positive and negative ions in the confined liquid in response to an applied electric field. A method of supplying power to a load using the capacitor and a method of making the capacitor is additionally disclosed.