Abstract: Systems and methods are disclosed for security through multi-party computation (MPC). In some examples, a system generates, at a first device and using a first private key share (of a plurality of private key shares). The plurality of private key shares each correspond to different devices. The system receives, from one or more additional devices, one or more additional partial signatures that are generated using one or more additional private key shares (of the plurality of private key shares). The system identifies that a total amount of partial signatures associated with the transaction is meets or exceeds a minimum threshold amount of partial signatures. The system aggregates the first partial signature and the one or more additional partial signatures to generate a signature, and facilitates processing of a transaction using the signature and a distributed ledger.

Abstract: Systems and methods are disclosed for security through multi-party computation (MPC). In some examples, a system generates, at a first device and using a first private key share (of a plurality of private key shares). The plurality of private key shares each correspond to different devices. The system receives, from one or more additional devices, one or more additional partial signatures that are generated using one or more additional private key shares (of the plurality of private key shares). The system identifies that a total amount of partial signatures associated with the transaction is meets or exceeds a minimum threshold amount of partial signatures. The system aggregates the first partial signature and the one or more additional partial signatures to generate a signature, and facilitates processing of a transaction using the signature and a distributed ledger.

Abstract: Systems and methods are disclosed for security through multi-party computation (MPC). In some examples, a system generates, at a first device and using a first private key share (of a plurality of private key shares). The plurality of private key shares each correspond to different devices. The system receives, from one or more additional devices, one or more additional partial signatures that are generated using one or more additional private key shares (of the plurality of private key shares). The system identifies that a total amount of partial signatures associated with the transaction is meets or exceeds a minimum threshold amount of partial signatures. The system aggregates the first partial signature and the one or more additional partial signatures to generate a signature, and facilitates processing of a transaction using the signature and a distributed ledger.

Abstract: Systems and methods are disclosed for security through multi-party computation (MPC). In some examples, a system generates, at a first device and using a first private key share (of a plurality of private key shares). The plurality of private key shares each correspond to different devices. The system receives, from one or more additional devices, one or more additional partial signatures that are generated using one or more additional private key shares (of the plurality of private key shares). The system identifies that a total amount of partial signatures associated with the transaction is meets or exceeds a minimum threshold amount of partial signatures. The system aggregates the first partial signature and the one or more additional partial signatures to generate a signature, and facilitates processing of a transaction using the signature and a distributed ledger.

Abstract: Systems and methods for multi-factor authentication are disclosed. In some examples, a system can receive a request for a transfer of an amount of a digital asset from a transferor to a transferee. The system can receive a first input through a first interactive user interface (UI) (that identifies at least a portion of the amount) to verify that at least the portion of the amount is correct, as a first factor of authentication for the transfer. The system can receive a second input through a second interactive UI (that identifies a first subset of a transferee address), and can verify that the second input matches the second subset of the transferee address, as a second factor of authentication for the transfer. The system can initiate the transfer of the amount from the transferor to the transferee in response to multi-factor authentication via the two factors of authentication.

Abstract: Compounds and methods for inhibiting STAT3.

Abstract: Voice data from a current conversation between a user and a voice-controlled user device can be used to determine a search constraint for searching a database. Other search constraints can be determined based at least in part on the current conversation, a previous conversation, and/or a previous action. Properties can be associated with the search constraints. Once the search constraints have been determined, a plurality of search query plans is determined and a first search query plan is executed to query the database.

Abstract: The invention describes DNA copy number alterations (CNAs), identifiable by technologies such as array-based comparative genomic hybridization (array CGH) or fluorescence in situ hybridization (FISH), that define distinct genetic subtypes of prostate cancer, and are useful for improved prognostication and treatment stratification for patients with prostate cancer.

Abstract: The present invention is a web-based transportation decision support system and geographic information system (GIS) application that leverages intelligent transportation system (ITS) information available from federal, state, local, and commercial transportation sources. The invention provides users with detailed road and rail information about routes and infrastructure characteristics, as well as real-time information from cameras, speed sensors, construction and accident reporting systems, and GIS based weather. Additionally, the invention provides users with the immediate ability to track and report surface shipments on an extremely accurate spatial data background.

Abstract: The present invention is a web-based transportation decision support system and geographic information system (GIS) application that leverages intelligent transportation system (ITS) information available from federal, state, local, and commercial transportation sources. The invention provides users with detailed road and rail information about routes and infrastructure characteristics, as well as real-time information from cameras, speed sensors, construction and accident reporting systems, and GIS based weather. Additionally, the invention provides users with the immediate ability to track and report surface shipments on an extremely accurate spatial data background.