Patents by Inventor Jonathan R. Dimmock

Jonathan R. Dimmock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives
    Patent number: 9669016
    Abstract: Embodiments are directed to compositions and methods for treating parasitic infections. Compounds have been identified from a library of anti-cancer drugs that serve as suitable agents for targeting trypanosomatids.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: June 6, 2017
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, UNIVERSITY OF SASKATCHEWAN
    Inventors: Rosa A. Maldonado, Miguel A. Vasquez, Jonathan R. Dimmock, Umashankar Das
  • Antiparasitic Effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives
    Publication number: 20160303105
    Abstract: Embodiments are directed to compositions and methods for treating parasitic infections. Compounds have been identified from a library of anti-cancer drugs that serve as suitable agents for targeting trypanosomatids.
    Type: Application
    Filed: June 27, 2016
    Publication date: October 20, 2016
    Inventors: Rosa A. MALDONADO, Miguel A. VASQUEZ, Jonathan R. DIMMOCK, Umashankar DAS
  • ANTIPARASITIC EFFECT OF BIS[3,5-BIS(BENZYLIDENE)-4-OXO-1-PIPERIDINYL]AMIDE DERIVATIVES
    Publication number: 20150290183
    Abstract: Embodiments are directed to compositions and methods for treating parasitic infections. Compounds have been identified from a library of anti-cancer drugs that serve as suitable agents for targeting trypanosomatids.
    Type: Application
    Filed: April 10, 2015
    Publication date: October 15, 2015
    Inventors: Rosa A. Maldonado, Miguel A. Vasquez, Jonathan R. Dimmock, Umashankar Das
  • Antineoplastic compounds
    Patent number: 7582655
    Abstract: The present invention relates to 4-piperidone derivatives represented by the following formula (I) and the acid addition salts thereof. The method of preparation and antineoplastic activity of the said compounds are disclosed. A number of the compounds possess submicromolar IC50 and CC50 values and have a selective toxicity for colon cancers and leukemic cells. In addition, many of the compounds are able to reverse multidrug resistance.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: September 1, 2009
    Assignee: University of Saskatchewan
    Inventors: Jonathan R. Dimmock, Umashankar Das
  • Mannich bases of conjugated styryl ketones
    Patent number: 6017933
    Abstract: Mannich bases of conjugated styryl ketones have been developed which are effective as cytotoxicity and anticancer agents, and which also have antifungal activity. Preferred compounds are those of the formula ##STR1## where R.sub.1 is Cl, CH.sub.3 or OCH.sub.3 and R.sub.2 is H or Cl. A compound of particular interest is (3-[3-(4-chlorophenyl)-2-propenoyl]-4-[2-(4-chlorophenyl)vinylene]-1-ethyl -4-piperidinol hydrochloride.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: January 25, 2000
    Assignees: University of Saskatchewan Technologies Inc., Wayne State University
    Inventors: Jonathan R. Dimmock, Elias K. Manavathu