Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: Method and apparatus for determining the deflection or curvature of a rotating blade, such as a wind turbine blade or a helicopter blade. Also, methods and apparatus for establishing an inertial reference system on a rotating blade.

Abstract: Structural health monitoring systems can be limited to a minimum number of sensors due to cost, complexity, and weight restrictions. Some embodiments described herein pertain to a load and damage identification techniques that utilize one sensor. Several passive force estimation techniques are presented. Some techniques use either the shape or the amplitude of the magnitude of the applied force in the frequency domain. Several techniques iteratively reduce an underdetermined set of equations of motion into many overdetermined systems of equations to solve for the force estimates. The techniques are shown to locate and quantify impulsive impacts with over 97% accuracy and non-impulsive impacts with at least 87% accuracy. Impacts not acting at a specific input degree of freedom are also accurately located depending on the distance away from the modeled input degrees of freedom, and damaging impact forces are quantified by making assumptions about the impulsive nature of the applied force.

Abstract: A portable, hand-held data terminal of modular structure includes a base module with a keyboard and a display screen. A data collection and communications module includes a stacked arrangement of a communications interface main circuit board, a radio and a laser scanner assembly which are housed in a housing shell which is attachable to the base module. The radio is mounted in spaced relationship to one side of the main circuit board, while the laser scanner assembly is mounted to the other side of the main circuit board. A support frame and a plurality of ground planes in the sandwiched main circuit board and a routing circuit board form an RF cage for shielding RF interference which may be generated by the radio. Also disclosed is a method for reducing the operational power consumption requirements of laser bar code scanners by analyzing reflected laser light in order to determine the presence of optically readable information sets.

Abstract: A hand-held optically readable information set reader having one or more photosensor arrays, at least one information set illuminator, and an information set image transfer system for projecting a readable image of an information set onto the one or more photosensor arrays.

Abstract: A hand-held optically readable information set reader having one or more photosensor arrays, at least one information set illuminator, and an information set image transfer system for projecting a readable image of an information set onto the one or more photosensor arrays.

Abstract: In the case of a pizza home delivery system, customer addresses and mapping information may be auomatically retrieved and displayed based on customer telephone number, and order data including an assigned order number may be imprinted on a label to be attached to each pizza container. Preferably, the system produces the order number in the form of a bar code on an adhesively backed label. Each driver may check out order for delivery by inserting his coded identification key at a bar code reader station and having the bar code labels scanned into the system, so that each order is assigned to a particular driver in a reliable and accurate manner. A voice synthesizer unit at the station can then remind the driver that the order includes beverages or more than one pizza container, and can advise the driver when the sum of the cash payments he has received for his deliveries exceeds a certain amount, making it advisable to deposit some of the accumulated cash before the next delivery.

Abstract: In laser bar code scanners bright sunlight tends to overpower the reflected laser light, drastically reducing the difference between bar code and background signals. In the present bar code reader, a plurality of light detectors are utilized with different spectral response characteristics at the wavelength of the incident laser beam, such that the differential response of the detectors tends to minimize the effect of background illumination. Narrowband optical filters with offset passbands may be used with conventional light sensors. As another example, filters with long wavelength transmission characteristics and offset cutoff wavelengths may be employed if necessary with a neutral density filter to provide balanced responses under broadband illumination.