Abstract: A method of managing a network of connected network devices can include detecting that a device descriptor file for a first network device has been updated and stored to a data store managed by a peer-to-peer network of computing systems; analyzing the updated device descriptor file stored to the data store; analyzing historical information stored in the data store regarding other device descriptor file updates related to the first network device or related to other network devices; performing predictive analytics processing on the results of the analyzing and generating a result; and storing the result of the performing predictive analytics processing to the data store.

Abstract: Compounds of formula I in which R1, R2, R3, each X, L, Y, Cy, Lp, D and n have the meanings as set out in the specification, and corresponding compounds in which the unsubstituted or substituted amidine group is replaced with an unsubstituted or substituted aminomethyl group, are useful as serine protease inhibitors.