Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: An ejector device and method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use is disclosed. The ejector device includes a housing, a reservoir disposed within the housing for receiving a volume of fluid, and an ejector mechanism in fluid communication with the reservoir and configured to eject a stream of droplets, the ejector mechanism comprising an ejector plate coupled to a generator plate and a piezoelectric actuator; the piezoelectric actuator being operable to oscillate the ejector plate, and thereby the generator plate, at a frequency and generate a directed stream of droplets.

Abstract: An ejector device and method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use is disclosed. The ejector device includes a housing, a reservoir disposed within the housing for receiving a volume of fluid, and an ejector mechanism in fluid communication with the reservoir and configured to eject a stream of droplets, the ejector mechanism comprising an ejector plate coupled to a generator plate and a piezoelectric actuator; the piezoelectric actuator being operable to oscillate the ejector plate, and thereby the generator plate, at a frequency and generate a directed stream of droplets.

Abstract: In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

Abstract: An ejector device and method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use is disclosed. The ejector device includes a housing, a reservoir disposed within the housing for receiving a volume of fluid, and an ejector mechanism in fluid communication with the reservoir and configured to eject a stream of droplets, the ejector mechanism comprising an ejector plate coupled to a generator plate and a piezoelectric actuator; the piezoelectric actuator being operable to oscillate the ejector plate, and thereby the generator plate, at a frequency and generate a directed stream of droplets.

Abstract: An ejector device and method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use is disclosed. The ejector device includes a housing, a reservoir disposed within the housing for receiving a volume of fluid, and an ejector mechanism in fluid communication with the reservoir and configured to eject a stream of droplets, the ejector mechanism comprising an ejector plate coupled to a generator plate and a piezoelectric actuator; the piezoelectric actuator being operable to oscillate the ejector plate, and thereby the generator plate, at a frequency and generate a directed stream of droplets.

Abstract: Analog interference filter devices and methods for isolation of desirable portions of a radio frequency signal. Signal compensation is used to provide desirable center frequency, passband width, ripple, rolloff, stopband and distortion performance. The filter is implemented with passive and/or active components.

Abstract: In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Abstract: In a piezoelectric ejector assembly, a piezoelectric actuator is attached to an ejector mechanism, while a drive signal generator and a controller are coupled to the actuator. The drive signal generator is configured to generate a drive signal for driving the actuator to oscillate the ejector assembly. The controller is configured to control the drive signal generator to drive the actuator at a resonant frequency of the ejector assembly, and an auto-tuning circuit is provided to define the optimum drive signal frequency.

Abstract: Analog interference filter devices and methods for isolation of desirable portions of a radio frequency signal. Signal compensation is used to provide desirable center frequency, passband width, ripple, rolloff, stopband and distortion performance. The filter is implemented with passive and/or active components.

Abstract: A piezoelectric ejector device is provided which is designed to minimize the intake of air into the device upon actuation by providing for laminar flow of the fluid. In an ejector mechanism that includes a generator plate and a piezoelectric actuator operable to directly or indirectly oscillate the generator plate, at a frequency to generate a directed stream of droplets of fluid, the generator plate includes a fluid facing surface, a droplet ejection surface, and a plurality of holes formed through its thickness between the surfaces. The plurality of holes are configured so as to minimize airflow through the plurality of openings from the droplet ejection surface to the fluid facing surface during generation of the directed stream of droplets by configuring the shape of the holes to minimize turbulence.

Abstract: Methods, systems, and computer readable media for wideband frequency and bandwidth tunable filtering are disclosed. According to one aspect, the subject matter described herein includes a wideband frequency and bandwidth tunable filter that splits a filter input signal into first and second input signals, modifies the first input signal to produce a first output signal, modifies the second input signal to produce a second output signal having an intermediate frequency response, and combines the first and second output signals while adjusting their relative phases and/or amplitudes to produce a filter output signal with the target frequency response. Adjustment includes splitting the second input signal into third and fourth input signals, which are modified and then combined to produce the second output signal having the intermediate frequency response.

Abstract: A directional heat diffusion assembly and method helps self-cool a transistor by forcing directional heat flow from a heat source, such as from a transistor, group of transistors, integrated circuit, or other integrated heat source, to a heat reservoir at a bottom surface and/or a top surface of the transistor, while also preventing heat flow towards the sidewall of the transistor. The directional heat flow occurs through a directional heat guide member that is comprised of alternating, layered arrangement of thermal insulative layers, and thermal conductive layers having varying thermal conductivities.

Abstract: Analog interference filter devices and methods for isolation of desirable portions of a radio frequency signal. Signal compensation is used to provide desirable center frequency, passband width, ripple, rolloff, stopband and distortion performance. The filter is implemented with passive and/or active components.

Abstract: Methods, systems, and computer readable media for wideband frequency and bandwidth tunable filtering are disclosed. According to one aspect, the subject matter described herein includes a wideband frequency and bandwidth tunable filter that splits a filter input signal into first and second input signals, modifies the first input signal to produce a first output signal, modifies the second input signal to produce a second output signal having an intermediate frequency response, and combines the first and second output signals while adjusting their relative phases and/or amplitudes to produce a filter output signal with the target frequency response. Adjustment includes splitting the second input signal into third and fourth input signals, which are modified and then combined to produce the second output signal having the intermediate frequency response.