Patents by Inventor Jonathan Sherman

Jonathan Sherman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220305279
    Abstract: A method and system of sensitization of cancerous cells in a volume is disclosed. A plasma tube including a pair of electrodes coupled to a power supply is provided. The plasma tube generates a plasma jet between the electrodes. A controller is coupled to a power supply to control a discharge voltage to the electrodes to generate the plasma jet and direct an electro-magnetic field at the volume having cancerous cells and normal cells for a sufficient time to sensitize the cancer cells. A treatment device applies a treatment such as TMZ to the sensitized cancer cells after the cancer cells are sensitized by the electro-magnetic field.
    Type: Application
    Filed: July 9, 2020
    Publication date: September 29, 2022
    Inventors: MICHAEL KEIDAR, DAYUN YAN, XIAOLIANG YAO, Li LIN, Vikas SONI, Jonathan SHERMAN
  • Publication number: 20220202489
    Abstract: A system and method of treating an area having cancerous cells. The system includes a plasma device to generate a plasma jet directed at the area having cancerous cells. A magnetic field generator generates a magnetic field directed at the area having cancerous cells. A controller is coupled to the plasma device and the magnetic field generator to control the plasma jet generated by the plasma device and control the magnetic field generated by the magnetic field generator.
    Type: Application
    Filed: January 5, 2022
    Publication date: June 30, 2022
    Inventors: Michael Keidar, Xiaoqian Cheng, Alexey Shashurin, Jonathan Sherman
  • Publication number: 20220168565
    Abstract: This disclosure relates to stabilized anti-cancer atmospheric plasma (CAP)-stimulated media, to methods for preparing such media, and to methods of treatment using such media.
    Type: Application
    Filed: December 8, 2021
    Publication date: June 2, 2022
    Inventors: Dayun YAN, Michael Keidar, Jonathan Sherman
  • Publication number: 20200253136
    Abstract: Protective bags having bag bodies formed by or with meshed fabrics can be used to protect potted plants from plant bugs. The protective bags are sized and shaped to protect both the plant top section and the plant root system or just the plant root system. Accessible seams or windows can be provided to access the interior of a bag for watering, feeding plant food, and/or pruning purposes. The protective bags can be sized and shaped to work with potted plants using soils or hydroponic systems.
    Type: Application
    Filed: February 7, 2020
    Publication date: August 13, 2020
    Inventors: Jonathan Sherman Stillman, Eric James Hibbard
  • Publication number: 20180296830
    Abstract: This disclosure relates to stabilized anti-cancer cold atmospheric plasma (CAP)-stimulated media, to methods for preparing such media, and to methods of treatment using such media.
    Type: Application
    Filed: October 26, 2016
    Publication date: October 18, 2018
    Inventors: Dayun YAN, Michael KEIDAR, Jonathan SHERMAN
  • Publication number: 20180271579
    Abstract: A micro-sized CAP (?CAP) employed to target glioblastoma tumors in the murine brain. Various plasma diagnostic techniques were applied to evaluate the physics of helium ?CAP such as electron density, discharge voltage, and optical emission spectroscopy. The direct and indirect effects of ?CAP on glioblastoma (U87MG-RedFluc) cancer cells in vitro were investigated and indicate that ?CAP-generated short- and long-lived species and radicals [i.e. hydroxyl radical (OH), hydrogen peroxide (H2O2), nitrite (NO2-), et al] with increasing tumor cell death in a dose-dependent fashion. Translation of these findings to an in vivo setting demonstrates that intracranial ?CAP is effective at preventing glioblastoma tumor growth in the mouse brain. The ?CAP device can be safely used in mice, resulting in suppression of tumor growth. These initial observations establish the ?CAP device as a potentially useful ablative therapy tool in the treatment of glioblastoma.
    Type: Application
    Filed: March 26, 2018
    Publication date: September 27, 2018
    Inventors: Michael Keidar, Zitong Chen, Jonathan Sherman, Colin N. Young, Hayk Simonyan, Jerome Canady
  • Publication number: 20180193093
    Abstract: A system and method of treating an area having cancerous cells. The system includes a plasma device to generate a plasma jet directed at the area having cancerous cells. A magnetic field generator generates a magnetic field directed at the area having cancerous cells. A controller is coupled to the plasma device and the magnetic field generator to control the plasma jet generated by the plasma device and control the magnetic field generated by the magnetic field generator.
    Type: Application
    Filed: June 28, 2016
    Publication date: July 12, 2018
    Inventors: Michael Keidar, Xiaoqian Cheng, Alexey Shashurin, Jonathan Sherman
  • Publication number: 20150034776
    Abstract: A line management device includes a body with a slot for receiving a tube and a base adapted to mount the body to a support surface. The base is configured to adapt to a non-planar surface without affecting the shape of the slot.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Inventors: Connor Feldpausch St.John, Cory Patrick Herbst, Mark Jonathan Sherman, Kelly Ann Stieler, Justin Lee Benacquisto
  • Publication number: 20130055153
    Abstract: In one implementation, content is received via a user interface and a plurality of descriptors are output in response to the content. Each descriptor is associated with a target from a plurality of targets. A target from the plurality of targets is selected in response to user input, and the content is provided to the target.
    Type: Application
    Filed: August 29, 2011
    Publication date: February 28, 2013
    Inventors: Jonathan Sherman, David Kempe
  • Patent number: 6873782
    Abstract: A high density, optical fiber array includes etched silicon front and guide masks anodicly bonded to high temperature glass die plate and/or spacer. Optical fibers secured in the front plate holes have the same thermal expansion coefficient as the masks and die/spacer plates to reduce the need for certain epoxy interplate zones which would have a different thermal expansion coefficient. Methods and a system for making the mask/plate stack are also disclosed along with various plate stacking arrangements and the front plate anodicly bonded to a glass lens array.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: March 29, 2005
    Assignee: Fiberguide Industries, Inc.
    Inventors: Randall Miller, Jonathan Sherman
  • Patent number: 6766086
    Abstract: Optical fiber array apparatus comprising housing front mask having a matrix of fiber seating openings each opening having one or more side walls. An optical fiber extends through each opening and means presses the fiber side surface into engagement with the one or more side walls to precisely position and secure the fiber. Bonding material then fills all voids in and around the opeining. In one embodiment, a clamping wafer behind the front mask moves to clamp the fibers to the front mask opening walls. In another, the front mask defines flexing arms with distal ends that clamp fibers to opening walls and in yet another elongated flexible members lie along front mask slots to clamp fibers in openings that communicate into the slots.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: July 20, 2004
    Assignee: Fiberguide Industries, Inc.
    Inventors: Jonathan Sherman, Theodore C. Rich, Irfan Camlibel
  • Publication number: 20040131326
    Abstract: A high density, optical fiber array includes etched silicon front and guide masks anodicly bonded to high temperature glass die plate and/or spacer. Optical fibers secured in the front plate holes have the same thermal expansion coefficient as the masks and die/spacer plates to reduce the need for certain epoxy interplate zones which would have a different thermal expansion coefficient. Methods and a system for making the mask/plate stack are also disclosed along with various plate stacking arrangements and the front plate anodicly bonded to a glass lens array.
    Type: Application
    Filed: October 16, 2003
    Publication date: July 8, 2004
    Inventors: Randall Miller, Jonathan Sherman
  • Patent number: 6757475
    Abstract: A method of making and an etchable wafer substrate for use in making optical fiber array plates includes forming a progressively increasing series of metrology holes when the plate holes are formed. The variation between designed plate hole diameter and actual plate hole diameter is determined by sequentially inserting a probe of known designed diameter into the metrology holes to determine the two size-adjacent metrology holes variation. The plate hole diameter can be determined by comparing one of the size-adjacent metrology hole diameter with the respective art work metrology hole diameter. Plate hole diameters can then be corrected for variation with further processing.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: June 29, 2004
    Assignee: Fiberguide Industries, Inc.
    Inventors: Jonathan Sherman, Randall Miller, Robert Sherman, Donald Russell
  • Publication number: 20040120884
    Abstract: Nanoparticulate titanium dioxide coating produced by educing flocculates of titanium dioxide nanoparticles from a titanyl sulfate solution and dispersing the nanoparticles in a polar sol-forming medium to make a sol suitable as a coating usable to impart photocatalytic activity, U.V. screening properties, and fire retardency to particles and to surfaces. The photocatalytic material and activity is preferably localized in dispersed concentrated nanoparticles, spots or islands both to save costs and leverage anti-microbial effects.
    Type: Application
    Filed: November 28, 2003
    Publication date: June 24, 2004
    Inventor: Jonathan Sherman
  • Patent number: 6704483
    Abstract: A high density optical fiber array assembly and assembly method includes a housing securing a front array mask etched with extreme precision to define openings arranged in a predetermined pattern. A series of guide plates form a series of fiber guide channels that align with the mask openings, which plates are stacked within the housing so that the bottom of one acts as a cover for the channels of another. Fibers can be tool inserted along the channels as one group, such as a row of fibers, or manually inserted and advanced sequentially. Alternately, the mask and guide plate stack are mounted to and within a mounting block and the mounting block assembly inserted into the assembly housing substantially all remaining voids in the housing are filled with bonding material.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: March 9, 2004
    Assignee: Fiberguide Industries, Inc.
    Inventors: Jonathan Sherman, Irfan Camlibel, Theodore C. Rich, Ernest J. Rich
  • Publication number: 20040013397
    Abstract: A method of making and an etchable wafer substrate for use in making optical fiber array plates includes forming a progressively increasing series of metrology holes when the plate holes are formed. The variation between designed plate hole diameter and actual plate hole diameter is determined by sequentially inserting a probe of known designed diameter into the metrology holes to determine the two size-adjacent metrology holes variation. The plate hole diameter can be determined by comparing one of the size-adjacent metrology hole diameter with the respective art work metrology hole diameter. Plate hole diameters can then be corrected for variation with further processing.
    Type: Application
    Filed: June 12, 2003
    Publication date: January 22, 2004
    Inventors: Jonathan Sherman, Randall Miller, Robert Sherman, Donald Russell
  • Patent number: 6674947
    Abstract: A system of making high density optical fiber arrays that includes securing the optical fiber ends in the housing front mask openings, then lapping the fiber ends and front mask forward surface to angle the fiber end front surfaces so that reflected wave energy does not interfere with optical signal data when transmitted during use. The opening pattern is preferably 2×2 to 128×128 or higher. Several alternate lap tool designs are disclosed including translational and rotating laps formed from solid bodies or a series of stacked plates. Standard slurry grinding and polishing compounds can be applied as desired. If a layer of epoxy originally covers the mask front face, it is removed by the lap tool as the fiber ends are lapped.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: January 6, 2004
    Assignee: Fiberguide Industries, Inc.
    Inventors: Irfan Camlibel, Jonathan Sherman, Theodore C. Rich, Ernest J. Rich
  • Patent number: 6653356
    Abstract: Nanoparticulate titanium dioxide coating produced by educing flocculates of titanium dioxide nanoparticles from a titanyl sulfate solution and dispersing the nanoparticles in a polar sol-forming medium to make a sol suitable as a coating usable to impart photocatalytic activity, U.V. screening properties, and fire retardency to particles and to surfaces. The photocatalytic material and activity is preferably localized in dispersed concentrated nanoparticles, spots or islands both to save costs and leverage anti-microbial effects.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: November 25, 2003
    Inventor: Jonathan Sherman
  • Patent number: 6562243
    Abstract: A water purification system and method suitable for use in swimming pools, spas, hot tubs, water storage tanks, wells and water cooling towers adds (i) an oxidizing agent, preferably granulated or caked chlorine, (ii) metal ions, preferably silver from a galvanic cell having a silver anode electrically connected to a cathode made from a metal of still higher electrochemical potential, normally platinum, and, optionally (iii) an algaecide, preferably chelated copper and/or phosphate-removing compound, and/or (iv) a phosphate-reducing compound, all in synergistic combination. The galvanic cell is preferably some tens of square centimeters in size and some tens of grams in weight, thereby liberating sufficient silver or copper ions so as to aid in treating a multi-thousand liter body of water, such as a swimming pool, for, typically under normal contamination, some weeks to months until the anode is consumed.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: May 13, 2003
    Inventor: Jonathan Sherman
  • Publication number: 20020197019
    Abstract: A high density optical fiber array assembly and assembly method includes a housing securing a front array mask etched with extreme precision to define openings arranged in a predetermined pattern. A series of guide plates form a series of fiber guide channels that align with the mask openings, which plates are stacked within the housing so that the bottom of one acts as a cover for the channels of another. Fibers can be tool inserted along the channels as one group, such as a row of fibers, or manually inserted and advanced sequentially. Alternately, the mask and guide plate stack are mounted to and within a mounting block and the mounting block assembly inserted into the assembly housing substantially all remaining voids in the housing are filled with bonding material.
    Type: Application
    Filed: June 7, 2002
    Publication date: December 26, 2002
    Inventors: Jonathan Sherman, Irfan Camlibel, Theodore C. Rich, Ernest J. Rich