Patents by Inventor Jonathan Sitrin

Jonathan Sitrin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BINDING AGENTS AND USES THEREOF
    Publication number: 20260042851
    Abstract: The present disclosure provides methods of degrading an EGFR protein on a target cell. The present disclosure further discloses antigen binding molecules that bind to an EGFR protein and a membrane-associated internalizing protein, such as ITGB6.
    Type: Application
    Filed: October 9, 2025
    Publication date: February 12, 2026
    Inventors: Shyra Jane Gardai, Hai Tran, Andrew Christopher Goodrich, Lisa Marshall, Isaac J. Rondon, Shruti Yadav, Jonathan Sitrin, Fortunato Ferrara
  • DEGRADATION OF cMET USING A BISPECIFIC BINDING AGENT
    Publication number: 20260022189
    Abstract: The present disclosure provides methods of degrading a cMET protein on a target cell. The present disclosure further discloses binding agents that bind to a cMET protein and a degrading protein.
    Type: Application
    Filed: May 6, 2025
    Publication date: January 22, 2026
    Inventors: Jonathan SITRIN, Hai TRAN, Lisa MARSHALL, Kenneth NG, Kimberly HOI, Shyra GARDAI, Katarina PANCE, Josef GRAMESPACHER, Rami HANNOUSH
  • DEGRADATION OF EGFR USING A BISPECIFIC BINDING AGENT
    Publication number: 20250388682
    Abstract: The present disclosure provides methods of degrading an EGFR protein on a target cell. The present disclosure further discloses bispecific binding agents that bind to an EGFR protein and a membrane-associated internalizing protein.
    Type: Application
    Filed: January 17, 2025
    Publication date: December 25, 2025
    Inventors: Katarina PANCE, Josef GRAMESPACHER, Rami HANNOUSH, Hai TRAN, Jonathan SITRIN, Lisa MARSHALL, Man-Tzu WANG, Kenneth NG, Shyra GARDAI
  • LAIR-1-BINDING AGENTS AND METHODS OF USE THEREOF
    Publication number: 20250179171
    Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind LAIR-1, including human LAIR-1, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.
    Type: Application
    Filed: January 23, 2025
    Publication date: June 5, 2025
    Inventors: Suzanne Christine Crawley, Bin Fan, Betty Chan Li, Lee Benjamin Rivera, James Robert Sissons, Jonathan Sitrin, Yan Wang, Xuan Zhao
  • LAIR-1-binding agents and methods of use thereof
    Patent number: 12240899
    Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind LAIR-1, including human LAIR-1, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: March 4, 2025
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Suzanne Christine Crawley, Bin Fan, Betty Chan Li, Lee Benjamin Rivera, James Robert Sissons, Jonathan Sitrin, Yan Wang, Xuan Zhao
  • LAIR-1-BINDING AGENTS AND METHODS OF USE THEREOF
    Publication number: 20220041711
    Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind LAIR-1, including human LAIR-1, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.
    Type: Application
    Filed: June 21, 2021
    Publication date: February 10, 2022
    Inventors: Suzanne Christine Crawley, Bin Fan, Betty Chan Li, Lee Benjamin Rivera, James Robert Sissons, Jonathan Sitrin, Yan Wang, Xuan Zhao