Abstract: The present disclosure relates to methods and systems to generate a modified feature map specific to a client. A template feature map may be modified based on usage data associated with a client. The template feature map may represent a visual representation of a plurality of features provided by an operator, each feature associated with a plurality of instructions to be processed for the client. The usage data may be compared with each feature to determine whether any feature is associated and/or utilized by the client. Based on determining whether the usage data indicates that any feature is associated and/or utilized by the client, the template feature map may be modified to perform an action to the template feature map indicating that a feature is associated and/or utilized by the client. A modified template feature map may be generated that is specific for a client.

Abstract: The present disclosure relates to methods and systems to generate a modified feature map specific to a client. A template feature map may be modified based on usage data associated with a client. The template feature map may represent a visual representation of a plurality of features provided by an operator, each feature associated with a plurality of instructions to be processed for the client. The usage data may be compared with each feature to determine whether any feature is associated and/or utilized by the client. Based on determining whether the usage data indicates that any feature is associated and/or utilized by the client, the template feature map may be modified to perform an action to the template feature map indicating that a feature is associated and/or utilized by the client. A modified template feature map may be generated that is specific for a client.

Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.

Abstract: The present disclosure relates to methods and systems to generate a modified feature map specific to a client. A template feature map may be modified based on usage data associated with a client. The template feature map may represent a visual representation of a plurality of features provided by an operator, each feature associated with a plurality of instructions to be processed for the client. The usage data may be compared with each feature to determine whether any feature is associated and/or utilized by the client. Based on determining whether the usage data indicates that any feature is associated and/or utilized by the client, the template feature map may be modified to perform an action to the template feature map indicating that a feature is associated and/or utilized by the client. A modified template feature map may be generated that is specific for a client.

Abstract: The present disclosure relates to methods and systems to generate a modified feature map specific to a client. A template feature map may be modified based on usage data associated with a client. The template feature map may represent a visual representation of a plurality of features provided by an operator, each feature associated with a plurality of instructions to be processed for the client. The usage data may be compared with each feature to determine whether any feature is associated and/or utilized by the client. Based on determining whether the usage data indicates that any feature is associated and/or utilized by the client, the template feature map may be modified to perform an action to the template feature map indicating that a feature is associated and/or utilized by the client. A modified template feature map may be generated that is specific for a client.

Abstract: An extraction system for distributing a test product in an extraction fluid, the system including a flow cell and a pump The flow cell has walls defining an internal passageway having an extraction region for holding the test product and also an upstream end and a downstream end between which the extraction region extends. The internal cross-sectional area of the upstream end is larger than the internal cross-sectional area of the downstream end the and extraction region tapers from the upstream end to the downstream end. The pump has an inlet in fluid communication with the downstream end and an outlet in fluid communication with the upstream end. The pump re-circulates extraction fluid from the downstream end back to the upstream end so as to progressively erode the test product and distribute the test product in the extraction fluid.

Abstract: The present subject matter relates generally to temperature sensors using one or a plurality of temperature sensing devices. Various embodiments of the present subject matter include a temperature sensor assembly. The temperature sensor assembly includes an enclosure having an inside surface and a temperature sensing device housed in the enclosure. A thermally conductive material connects a surface of the temperature sensing device directly to the inside surface of the enclosure in a side mounted manner to provide rapid thermal conduction from the enclosure to the temperature sensing device. In various embodiments, the temperature sensing device is a resistance temperature detector (RTD).

Abstract: An extraction system for distributing a test product in an extraction fluid, the system including a flow cell and a pump The flow cell has walls defining an internal passageway having an extraction region for holding the test product and also an upstream end and a downstream end between which the extraction region extends. The internal cross-sectional area of the upstream end is larger than the internal cross-sectional area of the downstream end the and extraction region tapers from the upstream end to the downstream end. The pump has an inlet in fluid communication with the downstream end and an outlet in fluid communication with the upstream end. The pump re-circulates extraction fluid from the downstream end back to the upstream end so as to progressively erode the test product and distribute the test product in the extraction fluid.

Abstract: The present subject matter relates generally to temperature sensors using a thin film element. Various embodiments of the present subject matter include a temperature sensor assembly. The temperature sensor assembly includes an enclosure having an inside surface and a thin film element housed in the enclosure. A thermally conductive material connects a surface of the thin film element directly to the inside surface of the enclosure in a side mounted manner to provide rapid thermal conduction from the enclosure to the thin film element. In various embodiments, the thin film element is a resistance temperature detector (RTD).

Abstract: A method of valuation of large groups of assets by selecting a lowest variation assumption for asset valuation in order to limit risk includes the steps of evaluating assets by all known valuation methodologies which have merit for those particular assets, selecting the valuation methodology which is most accurate for the assets being evaluated and assigning values to the assets. Individual asset values are developed and listed in tables so that individual asset values can be taken from the tables and grouped in any desired manner. The asset s are divided into categories by credit variable and then rated individually.

Abstract: A method of valuation of large groups of assets by partial full underwriting, partial sample underwriting and inferred values of the remainder using an iterative and adaptive supervised and unsupervised statistical evaluation of all assets and statistical inferences drawn from the evaluation and applied to generate the inferred asset values. Individual asset values are developed and listed in realtional tables so that individual asset values can be rapidly taken from the tables and quickly grouped in any desired or prescribed manner for bidding purposes. The assets are collected into a database, divided into categories by credit variable, subdivided by ratings as to those variables and then rated individually. The assets are then regrouped according to a bidding grouping and a collective valuations established by cumulating the individual valuations.

Abstract: A testing apparatus and method for characterizing the aerodynamic particle size of an atomized medicament emitted from a metered dose inhaler unit during testing with a particle characterization device in which the testing apparatus includes a first clamp of a first fixture in removable clamping and locking engagement with a throat, which is in fluid communication with a particle characterization device, a second clamp in removable clamping and locking engagement with a delivery device of the metered dose inhaler unit having a canister, containing atomized medicament, operatively loaded therein, an alignment mechanism that removably couples the first fixture to the second fixture at an aligned position therefore causing the throat to be in fluid communication with the delivery device, and an actuation assembly mounted to the first fixture having means that operatively thrusts the canister into the delivery device of the metered dose inhaler unit, thus releasing atomized medicament.

Abstract: A method of valuation of large groups of assets by selecting a lowest variation assumption for asset valuation in order to limit risk includes the steps of evaluating assets by all known valuation methodologies which have merit for those particular assets, selecting the valuation methodology which is most accurate for the assets being evaluated and assigning values to the assets. Individual asset values are developed and listed in tables so that individual asset values can be taken from the tables and grouped in any desired manner. The asset s are divided into categories by credit variable and then rated individually.

Abstract: A method of valuation of large groups of assets by partial full underwriting, partial sample underwriting and inferred values of the remainder using an iterative and adaptive supervised and unsupervised statistical evaluation of all assets and statistical inferences drawn from the evaluation and applied to generate the inferred asset values. Individual asset values are developed and listed in realtional tables so that individual asset values can be rapidly taken from the tables and quickly grouped in any desired or prescribed manner for bidding purposes.. The assets are collected into a database, divided into categories by credit variable, subdivided by ratings as to those variables and then rated individually. The assets are then regrouped according to a bidding grouping and a collective valuations established by cumulating the individual valuations.