Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, an endoprosthesis includes a first portion having a first width, and a second portion having a second width different than the first width, wherein the first and second portions have different grain sizes.

Abstract: Alloy compositions, including devices and instruments that include the compositions, are disclosed. The compositions have high hardness, strength, corrosion resistance, and biocompatibility. The compositions can be used to manufacture, for example, medical devices and products.

Abstract: A medical device includes an alloy having chromium, niobium, and platinum, wherein the alloy forms at least a portion of the medical device.

Abstract: Stent delivery system and method of manufacturing same. In one embodiment, the stent delivery system comprises an inner catheter. A handle is disposed at the proximal end of the inner catheter, and an enlarged tip is disposed at the distal end thereof. A stent engaging sleeve coaxially surrounds and is secured to a portion of the inner catheter proximally contiguous to the tip. The stent engaging sleeve is used to frictionally engage a stent mounted thereover in such a way as to prevent the stent, during deployment, from sliding proximally relative to the inner catheter. The system additionally comprises a self-expandable stent of the type comprising a knitted mesh of nitinol wire flexible in both the radial and longitudinal axes. The stent is mounted over the stent engaging sleeve in a longitudinally stretched state and is maintained, until deployment, in the stretched state by a stent restraining sleeve.

Abstract: Endoprostheses including composites, and methods of making the endoprosthesis, are disclosed. The composites include at least a first material and a second material having different chemical compositions from each other.

Abstract: The invention relates to a stent-graft with a bioabsorbable structure and a permanent graft for luminal support and treatment of arterial fistulas, occlusive disease, and aneurysms. The bioabsorbable structure is formed from braided filaments of materials such as PLA, PLLA, PDLA, and PGA and the graft is formed from materials such as PET, ePTFE, PCU or PU.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, a medical device includes a composite having a metallic matrix and a plurality of particles in the matrix, the particles and the matrix having different compositions.

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a medical device includes an alloy having tantalum, tungsten, zirconium and niobium. For example, the alloy can include from about 20% to about 40% by weight of tantalum, from about 0.5% to about 9% by weight of tungsten, and from about 0.5% to about 10% by weight of zirconium.

Abstract: A self-expanding stent formed from helically wound and braided filaments of bioabsorbable polymers such as PLA, PLLA, PDLA, and PGA.

Abstract: Medical devices, such as stents, and methods of making the devices, are described. In some embodiments, the invention features a medical device that includes a member having a first portion and a second portion that define an electrically conductive loop. The first portion is adapted to break or erode after expansion of the medical device, and the second portion is not adapted to break or erode after expansion of the medical device. The breaking or erosion of the first portion breaks the electrically conductive loop.

Abstract: Embodiments of the present invention relate to medical devices that provide signals to diagnostic equipment such that functionality of an implantable member can be determined. In particular, various designs and structures are utilized to signal tissue growth on an implantable member such as a stent. The tissue growth can limit flow through the stented lumen. If the growth has a thickness above a certain limit, a signal can be detected by diagnostic equipment such that a proper diagnosis can be made.

Abstract: Medical devices, for example, implantable devices such as endoprostheses, include a composite material having a polymer.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, an endoprosthesis includes a first portion having a first width, and a second portion having a second width different than the first width, wherein the first and second portions have different grain sizes.

Abstract: A delivery device for delivering an implantable endoprosthesis with an occlusion region for occluding fluid flow to a desired location in a body lumen. The delivery device includes an outer sleeve and an inner tube terminating at a distal tip. The distal tip is made of one of a dissolvable, bioabsorbable, or deformable material. Upon deployment of the endoprosthesis at the desired location, the shape of the distal tip is altered to a different shape and withdrawn through the constricted region of the endoprosthesis.

Abstract: A temporary bioabsorbable-radiopaque marker for use on an implantable endoprosthesis. The bioabsorbable-radiopaque marker is adapted to be disposed on or adjacent an implantable endoprosthesis in a body lumen for a predetermined amount of time until the bioabsorbable and radiopaque materials are absorbed or dispersed in the body.

Abstract: A method of making a stent includes providing a tubular member having a first layer, the first layer and the tubular member having different compositions, removing a portion of the tubular member, and removing a portion of the first layer from the tubular member.

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, the devices are made using a laser forming process.

Abstract: Alloy compositions, including devices and instruments that include the compositions, are disclosed. The compositions have high hardness, strength, corrosion resistance, and biocompatibility. The compositions can be used to manufacture, for example, medical devices and products.

Abstract: Medical devices, such as stents, and methods of the devices are described.

Abstract: Medical stents having valves and their methods of manufacture are disclosed. The valve may be basket-shaped and formed integral to a medical stent to prevent undesirable backflow across the valve. The valve can be formed by converting the braided wires of the stent, by providing elastomeric material onto a mold or fixture to form an elastomeric valve, or by attaching a gasket valve. The valve is normally closed but configured to allow easy opening in response to a predetermined condition.