Abstract: An apparatus for depositing a food product comprising a nozzle having a pressurised chamber and a food product outlet; a valve needle movable relative between a closed position and to one of a plurality of discrete open positions; and an actuator configured to set the position of the valve needle relative to the outlet, wherein the nozzle is further able to rotate in use to change the direction of flow of a food product being deposited by the apparatus.

Abstract: Echogenic liposomes (ELIP) formulated with an at least partially pegylated phospholipid bi-layer shell, encapsulated nitric oxide, and encapsulated perfluorocarbon of the formula CxFy in a ratio of about 1:1 by volume, wherein X is greater than or equal to 3, are disclosed, along with methods for treating a patients suffering from cardiovascular disease by administering the ELIP at a site remote from the target diseased section, monitoring presence of the ELIP at the target diseased section, and administering ultrasound upon detection of presence such that bioactive NO is released at the target diseased section.

Abstract: A blood clot obstruction of a coronary artery causing myocardial infarction is treated by sonothrombolysis by transmitted therapeutic ultrasound to the coronary artery in synchronism with the heart cycle. Therapeutic transmission may be at the same phase of consecutive or non-consecutive heart cycles. To allow for microbubble replenishment, two or more different patterns of therapeutic energy may be used. A coronary artery and its downstream microvasculature may be treated at the same time by using different heart cycle timing or different beam patterns or both for the two therapeutic sites.

Abstract: An ECG system acquires ECG signals for the production of ECG lead data which is analyzed for ST elevation characteristics. The ST elevation information is further analyzed to identify a coronary artery or region of the myocardium which may be affected by an obstruction or occlusion. The identity of an obstructed coronary artery or affected myocardium is related to a spatial location in an ultrasound image of the heart to target an ultrasound probe at the coronary artery or myocardial region which may be obstructed or affected by an obstruction. Sonoreperfusion is then performed at the coronary artery or myocardial region targeted by the ultrasound probe.

Abstract: The invention is a depositing device for depositing flowable food containing gas comprising a pressurized feed N line conveying flowable food containing gas under pressure into the food; piston means operatively connected to the feed line comprising a piston and a chamber; an outlet to deliver food at the atmospheric pressure into molds. The device comprises a pressure retaining means arranged to retain the product in the chamber at the same pressure as the line pressure and to deliver the product through the outlet as pressure in the chamber increases from the line pressure upon descent of the piston in the chamber.

Abstract: Echogenic liposomes (ELIP) formulated with an at least partially pegylated phospholipid bi-layer shell, encapsulated nitric oxide, and encapsulated perfluorocarbon of the formula CxFy in a ratio of about 1:1 by volume, wherein X is greater than or equal to 3, are disclosed, along with methods for treating a patients suffering from cardiovascular disease by administering the ELIP at a site remote from the target diseased section, monitoring presence of the ELIP at the target diseased section, and administering ultrasound upon detection of presence such that bioactive NO is released at the target diseased section.

Abstract: An apparatus for depositing a liquid, semi-liquid or semi-solid food product. The apparatus comprises a fixed volume chamber for receiving the food product under a positive pressure, the chamber being defined by chamber walls, one of the chamber walls being provided with an outlet orifice for depositing the food product, the outlet orifice being provided with a first sealing surface. The apparatus also comprises a valve spindle arranged for reciprocating movement within the chamber, the length direction of the valve spindle extending substantially perpendicular to the chamber wall in which the outlet orifice is provided, a first end of the valve spindle being provided with a second sealing surface. The second sealing surface of the valve spindle is arranged for abutting the first sealing surface of the outlet orifice to thereby close the outlet orifice.

Abstract: The invention is a depositing device for depositing flowable food containing gas comprising a pressurized feed N line conveying flowable food containing gas under pressure into the food; piston means operatively connected to the feed line comprising a piston and a chamber; an outlet to deliver food at the atmospheric pressure into moulds. The device comprises a pressure retaining means arranged to retain the product in the chamber at the same pressure as the line pressure and to deliver the product through the outlet as pressure in the chamber increases from the line pressure upon descent of the piston in the chamber.

Abstract: The invention is a depositing device (5) for depositing flowable food containing gas comprising a pressurized feed line conveying flowable food containing gas under pressure into the food; piston (60) means operatively connected to the feed line comprising a piston and a chamber (61); an outlet to deliver food at the atmospheric pressure into molds (85). The device comprises a pressure retaining means (9) arranged to retain the product in the chamber at the same pressure as the line pressure and to deliver the product through the outlet as pressure in the chamber increases from the line pressure upon descent of the piston in the chamber.

Abstract: An apparatus for depositing a liquid, semi-liquid or semi-solid food product. The apparatus comprises a fixed volume chamber for receiving the food product under a positive pressure, the chamber being defined by chamber walls, one of the chamber walls being provided with an outlet orifice for depositing the food product, the outlet orifice being provided with a first sealing surface. The apparatus also comprises a valve spindle arranged for reciprocating movement within the chamber, the length direction of the valve spindle extending substantially perpendicular to the chamber wall in which the outlet orifice is provided, a first end of the valve spindle being provided with a second sealing surface. The second sealing surface of the valve spindle is arranged for abutting the first sealing surface of the outlet orifice to thereby close the outlet orifice.

Abstract: An electronic telephone directory system is described. Each entry in the directory has summary information, category specific information, and associated categories. The system displays a different view of the category specific information depending on categories associated with an entry. For example, a restaurant may have a detailed view that shows its menu and specials whereas the detailed view for a taxi service shows the company's coverage area. The directory periodically updates using cellular networks but generally operates without an active network connection.

Abstract: Compounds of formula (I): wherein: R2 is H or an optionally substituted C1-4 alkyl group; Y is either —(CH2)n—X—, where n is 1 or 2 and X is O, S, S(?O), S(?O)2, or NRN1, where RN1 is selected from H or optionally substituted C1-4 alkyl, or Y is —C(?O)NRN2—, where RN2 is selected from H, and optionally substituted C1-7 alkyl or C5-20 aryl; R3 is an optionally substituted C6 aryl group linked to a further optionally substituted C6 aryl group, wherein if both C6 aryl groups are benzene rings, there may be an oxygen bridge between the two rings, bound adjacent the link on both rings; A is a single bond or a C1-3 alkylene group; and R5 is either: (i) carboxy; (ii) a group of formula (II): (iii) a group of formula (III): wherein R is optionally substituted C1-7 alkyl, C5-20 aryl or NRN3RN4, where RN3 and RN4 are independently selected from optionally substituted C1-4 alkyl; (iv) tetrazol-5-yl.

Abstract: The invention is a depositing device (5) for depositing flowable food containing gas comprising a pressurized feed line conveying flowable food containing gas under pressure into the food; piston (60) means operatively connected to the feed line comprising a piston and a chamber (61); an outlet to deliver food at the atmospheric pressure into moulds (85). The device comprises a pressure retaining means (9) arranged to retain the product in the chamber at the same pressure as the line pressure and to deliver the product through the outlet as pressure in the chamber increases from the line pressure upon descent of the piston in the chamber.

Abstract: A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R2 and R5 is: (i) H or an optionally substituted C1-4 alkyl group; or (ii) an optionally substituted C5-7 aryl; and the other of R2 and R5 is the other group; m and n can be 0 or 1, and m+n=1 or 2 RN is H or optionally substituted C1-4 alkyl R3 is either: (i) carboxy; (ii) a group of formula (II): (iii) a group of formula (III): wherein R is optionally substituted C1-7 alkyl, C5-20 aryl, or NRN3RN4, where RN3 and RN4 are independently selected from optionally substituted C1-4 alkyl; or (iv) tetrazol-5-yl.

Abstract: Compounds of formula (I): wherein: R2 is H or an optionally substituted C1-4 alkyl group; Y is either —(CH2)n—X—, where n is 1 or 2 and X is O, S, S(?O), S(?O)2, or NRN1, where RN1 is selected from H or optionally substituted C1-4 alkyl, or Y is —C(?O)NRN2—, where RN2 is selected from H, and optionally substituted C1-7 alkyl or C5-20 aryl; R3 is an optionally substituted C6 aryl group linked to a further optionally substituted C6 aryl group, wherein if both C6 aryl groups are benzene rings, there may be an oxygen bridge between the two rings, bound adjacent the link on both rings; A is a single bond or a C1-3 alkylene group; and R5 is either: (i) carboxy; (ii) a group of formula (II): ; or (iii) a group of formula (III): wherein R is optionally substituted C1-7 alkyl, C5-20 aryl or NRN3RN4, where RN3 and RN4 are independently selected from optionally substituted C1-4 alkyl; (iv) tetrazol-5-yl.

Abstract: A method to create within a computer system, an association between the appearance of a token and one or more stored files for the purpose of retrieving and presenting said one or more stored files, comprising the steps of: measuring said appearance of said token; creating a token identity from the obtained measurement; storing said token identity in an identity store; associating within said computer system, said stored file with said token identity; subsequently measuring said appearance of said token; creating a subsequent identity for said token using subsequent measurement data obtained from said subsequent measurement; searching in said identity store for a match with said subsequent identity; upon the location of a match, retrieving said one or more stored files; and presenting said retrieved file to a user.

Abstract: Novel 4,5-? epoxy-morphinan compounds are disclosed. Pharmaceutical compositions containing the 4,5-? epoxy-morphinan compounds and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, inter alia, as modulators of opioid receptors.

Abstract: A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein: R5is an optionally substituted C5-20 aryl or C4-20 alkyl group; A is selected from the group consisting of: wherein X and Y are selected from the group consisiting of: O and CR3; S and CR3; NH and CR3; NH and N; O and N; S and N; N and S; and N and O.

Abstract: A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R2 and R5 is: (i) H or an optionally substituted C1-4 alkyl group; or (ii)an optionally substituted C5-7 aryl; and the other of R2 and R5 is the other group; m and n can be 0 or 1, and m+n=1 or 2 RN is H or optionally substituted C1-4 alkyl R3 is either: (i) carboxy; (ii) a group of formula (II): (iii) a group of formula (III): wherein R is optionally substituted C1-7 alkyl, C5-20 aryl, or NRN3RN4, where RN3 and RN4 are independently selected from optionally substituted C1-4 alkyl; or (iv) tetrazol-5-yl.