Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Computer implemented methods are disclosed for acquiring, using a processor, digital data of a portion of an elongate object, and identifying, using a processor, a centerline connecting a plurality of points within the portion of the elongate object. The methods also may include defining a first half-plane along the centerline, traversing a predetermined angular distance in a clockwise or counter clockwise direction from the first half-plane to a second half-plane to define an angular wedge, and calculating, using a processor, a view of the angular wedge between the first half-plane and the second half-plane and generating an electronic view of the angular wedge.

Abstract: Kits, methods and systems for providing a service to provide a subject with information regarding the state of a subject's DNA damage. Collection, processing and analysis of samples are also described.

Abstract: Computer implemented methods are disclosed for acquiring, using a processor, digital data of a portion of an elongate object, and identifying, using a processor, a centerline connecting a plurality of points within the portion of the elongate object. The methods also may include defining a first half-plane along the centerline, traversing a predetermined angular distance in a clockwise or counter clockwise direction from the first half-plane to a second half-plane to define an angular wedge, and calculating, using a processor, a view of the angular wedge between the first half-plane and the second half-plane and generating an electronic view of the angular wedge.

Abstract: The present disclosure is directed to using patients' imaging of a tubular structure to generate a series of maximum intensity projection views of segments of the tubular structure and assembling the views to provide a complete circumferential visualization of the tubular structure. Such views may be used to generate patient-specific models of flow within the tubular structure, predict medical events (e.g. cardiac, pulmonary, respiratory), including plaque rupture and/or myocardial infarction.

Abstract: Computer implemented methods are disclosed for acquiring, using a processor, digital data of a portion of an elongate object, and identifying, using a processor, a centerline connecting a plurality of points within the portion of the elongate object. The methods also may include defining a first half-plane along the centerline, traversing a predetermined angular distance in a clockwise or counter clockwise direction from the first half-plane to a second half-plane to define an angular wedge, and calculating, using a processor, a view of the angular wedge between the first half-plane and the second half-plane and generating an electronic view of the angular wedge.

Abstract: Various embodiments of the present disclosure relate generally to medical imaging and related methods. More specifically, particular embodiments of the present disclosure relate to systems and methods for visualizing elongated structures.

Abstract: The invention provides systems to control gene expression or activity using target molecules.

Abstract: Computer implemented methods are disclosed for acquiring, using a processor, digital data of a portion of an elongate object, and identifying, using a processor, a centerline connecting a plurality of points within the portion of the elongate object. The methods also may include defining a first half-plane along the centerline, traversing a predetermined angular distance in a clockwise or counter clockwise direction from the first half-plane to a second half-plane to define an angular wedge, and calculating, using a processor, a view of the angular wedge between the first half-plane and the second half-plane and generating an electronic view of the angular wedge.

Abstract: A system, computer-readable storage medium storing at least one program, and a computer-implemented method for confirming authorship of documents is presented. A first document hosted on a first website of a first domain is accessed, the first document being linked to a second document through at least one link, and a respective link including a first predefined authorship attribute asserting authorship of a respective document including the respective link by a respective entity associated with a respective target document of the respective link. Authorship of the first document by an entity associated with the second document is conditionally confirmed when the second document includes a second link to the first website of the first domain, the second link including a second predefined authorship attribute indicating that the entity associated with the second document is an author of or contributor to content at the first website of the first domain.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: Systems and methods are disclosed for providing a cardiovascular score for a patient. A method includes receiving, using at least one computer system, patient-specific data regarding a geometry of multiple coronary arteries of the patient; and creating, using at least one computer system, a three-dimensional model representing at least portions of the multiple coronary arteries based on the patient-specific data. The method also includes evaluating, using at least one computer system, multiple characteristics of at least some of the coronary arteries represented by the model; and generating, using at least one computer system, the cardiovascular score based on the evaluation of the multiple characteristics. Another method includes generating the cardiovascular score based on evaluated multiple characteristics for portions of the coronary arteries having fractional flow reserve values of at least a predetermined threshold value.

Abstract: The invention provides systems and methods for transcriptional control which employ target molecules.

Abstract: A system, computer-readable storage medium storing at least one program, and a computer-implemented method for confirming authorship of documents is presented. A first document hosted on a first website of a first domain is accessed, the first document being linked to a second document through at least one link, and a respective link including a first predefined authorship attribute asserting authorship of a respective document including the respective link by a respective entity associated with a respective target document of the respective link. Authorship of the first document by an entity associated with the second document is conditionally confirmed when the second document includes a second link to the first website of the first domain, the second link including a second predefined authorship attribute indicating that the entity associated with the second document is an author of or contributor to content at the first website of the first domain.

Abstract: The present invention automatically generates an object model from a dimensional model. The object model can then be queried using object oriented expressions.

Abstract: Architecture for cell-based security on a per-user basis. A security model for this capability includes not only dimension level tables, but is extended to include cell level tables. The security model can include existing dimension tables, plus cell security tables that include a cell permissions table, a cell qualifiers table and a table that includes both the cell permissions table, a cell qualifiers. Metadata associated with the security applied to the cells for a given user can be stored locally in a local metadata store for retrieval and application against a data cube that an authenticated and authorized user is querying. In a specific implementation, the cell level security is employed in a performance management server application, where authentication is performed remotely by an authentication service, but the authorization function is performed local to the performance management server application.